FR2376850A2 - 1-(2-(halogenophenylthio)-4-(p-chloro-ou-fluorophenyl)n-butyl) imidazoles et application antimicrobienne - Google Patents

1-(2-(halogenophenylthio)-4-(p-chloro-ou-fluorophenyl)n-butyl) imidazoles et application antimicrobienne

Info

Publication number
FR2376850A2
FR2376850A2 FR7800480A FR7800480A FR2376850A2 FR 2376850 A2 FR2376850 A2 FR 2376850A2 FR 7800480 A FR7800480 A FR 7800480A FR 7800480 A FR7800480 A FR 7800480A FR 2376850 A2 FR2376850 A2 FR 2376850A2
Authority
FR
France
Prior art keywords
halogenophenylthio
imidazoles
fluorophenyl
chloro
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7800480A
Other languages
English (en)
Other versions
FR2376850B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/758,094 external-priority patent/US4078071A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of FR2376850A2 publication Critical patent/FR2376850A2/fr
Application granted granted Critical
Publication of FR2376850B2 publication Critical patent/FR2376850B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Composé de formule :
FR7800480A 1977-01-10 1978-01-09 1-(2-(halogenophenylthio)-4-(p-chloro-ou-fluorophenyl)n-butyl) imidazoles et application antimicrobienne Granted FR2376850A2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/758,094 US4078071A (en) 1976-03-08 1977-01-10 Derivatives of substituted N-alkyl imidazoles

Publications (2)

Publication Number Publication Date
FR2376850A2 true FR2376850A2 (fr) 1978-08-04
FR2376850B2 FR2376850B2 (fr) 1980-02-15

Family

ID=25050465

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7800480A Granted FR2376850A2 (fr) 1977-01-10 1978-01-09 1-(2-(halogenophenylthio)-4-(p-chloro-ou-fluorophenyl)n-butyl) imidazoles et application antimicrobienne

Country Status (10)

Country Link
JP (1) JPS53135976A (fr)
CH (1) CH636089A5 (fr)
DE (1) DE2800755A1 (fr)
FR (1) FR2376850A2 (fr)
GB (1) GB1567431A (fr)
HK (1) HK17681A (fr)
IT (1) IT1111401B (fr)
MY (1) MY8100370A (fr)
NL (1) NL184160C (fr)
SE (1) SE443783B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005980A2 (fr) * 1978-05-30 1979-12-12 Syntex (U.S.A.) Inc. Dérivés de N-alcoyl(substitué)-imidazoles, procédé pour leur préparation et ces composés pour utilisation pharmaceutique

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55160767A (en) * 1979-05-31 1980-12-13 Idota Yutaka Imidazole derivative
DE3369984D1 (en) * 1982-07-12 1987-04-09 Searle & Co 1-(1h-imidazolyl), 1-n-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them
GB8316444D0 (en) * 1983-06-16 1983-07-20 Ici Plc Heterocycle compounds
HUP0400270A3 (en) * 2004-01-27 2007-09-28 Richter Gedeon Nyrt High purity butoconazole nitrate having a predetermined particle size and process for the production of the same
JP6229896B2 (ja) * 2013-01-21 2017-11-15 国立大学法人大阪大学 フェノキシアルキルアミン化合物
US11185548B2 (en) 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
MX3866E (es) * 1975-07-28 1981-08-26 Syntex Inc Metodo mejorado para preparar derivados de imidazoles n-alquil sustituidos
JPS6028820A (ja) * 1983-07-26 1985-02-14 Daishiro Fujishima 脱酸素剤

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005980A2 (fr) * 1978-05-30 1979-12-12 Syntex (U.S.A.) Inc. Dérivés de N-alcoyl(substitué)-imidazoles, procédé pour leur préparation et ces composés pour utilisation pharmaceutique
FR2427330A1 (fr) * 1978-05-30 1979-12-28 Syntex Inc Nouveaux derives de n-alkylimidazoles substitues, leur procede de production, medicament et produit phytosanitaire les contenant
EP0005980A3 (en) * 1978-05-30 1980-01-09 Syntex (U.S.A.) Inc. Derivatives of substituted n-alkyl imidazoles, their preparation and pharmaceutical use

Also Published As

Publication number Publication date
HK17681A (en) 1981-05-08
SE443783B (sv) 1986-03-10
JPS635388B2 (fr) 1988-02-03
SE7800111L (sv) 1978-07-11
JPS53135976A (en) 1978-11-28
IT1111401B (it) 1986-01-13
NL184160B (nl) 1988-12-01
MY8100370A (en) 1981-12-31
NL184160C (nl) 1989-05-01
CH636089A5 (en) 1983-05-13
IT7867025A0 (it) 1978-01-09
NL7800097A (nl) 1978-07-12
GB1567431A (en) 1980-05-14
FR2376850B2 (fr) 1980-02-15
DE2800755A1 (de) 1978-07-13
DE2800755C2 (fr) 1989-09-07

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0221, 920519

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0221, 780109

CL Concession to grant licences