JPS55160767A - Imidazole derivative - Google Patents

Imidazole derivative

Info

Publication number
JPS55160767A
JPS55160767A JP6819079A JP6819079A JPS55160767A JP S55160767 A JPS55160767 A JP S55160767A JP 6819079 A JP6819079 A JP 6819079A JP 6819079 A JP6819079 A JP 6819079A JP S55160767 A JPS55160767 A JP S55160767A
Authority
JP
Japan
Prior art keywords
formula
halogen
compound
imidazole
methylphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6819079A
Other languages
Japanese (ja)
Inventor
Yoshiki Hamada
Tomiyoshi Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP6819079A priority Critical patent/JPS55160767A/en
Publication of JPS55160767A publication Critical patent/JPS55160767A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An imidazole derivative of formula I (R is lower alkyl or halogen; X is halogen; Y is H or halogen), or its pharmaceutically acceptable salt.
EXAMPLE: 1-[4-(4-Methylphenyl)-2-(2,6-dichlorophenylthio)-n-butyl]-1H-imidazole.
USE: Remedy and prophylactic for various infectious diseases or additive for animal feed. It has excellent antimicrobial activity against gram-positive bacteria, gram- negative bacteria, and especially fungi.
PROCESS: The compound of formula I is prepared by (1) reacting a compound of formula II such as 1-[4-(4-methylphenyl)-2-hydroxy-n-butyl]-1H-imidazole with thionyl chloride, and (2) reacting the product with a compound of formula III such as 2,6-dichlorothiophenol in an organic solvent such as acetone in the presence of K2CO3.
COPYRIGHT: (C)1980,JPO&Japio
JP6819079A 1979-05-31 1979-05-31 Imidazole derivative Pending JPS55160767A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6819079A JPS55160767A (en) 1979-05-31 1979-05-31 Imidazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6819079A JPS55160767A (en) 1979-05-31 1979-05-31 Imidazole derivative

Publications (1)

Publication Number Publication Date
JPS55160767A true JPS55160767A (en) 1980-12-13

Family

ID=13366609

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6819079A Pending JPS55160767A (en) 1979-05-31 1979-05-31 Imidazole derivative

Country Status (1)

Country Link
JP (1) JPS55160767A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5217472A (en) * 1975-07-28 1977-02-09 Syntex Inc Substituted nnalkylimidazole derivatives
JPS5390263A (en) * 1977-01-19 1978-08-08 Syntex Inc Compound process for preparing same composition containing same and method of inhibiting mould
JPS53135976A (en) * 1977-01-10 1978-11-28 Syntex Inc 11**22halophenylthio**44*chlorooorr fluorophenyl**nnbutyl*imidazole process for preparing same and application method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5217472A (en) * 1975-07-28 1977-02-09 Syntex Inc Substituted nnalkylimidazole derivatives
JPS53135976A (en) * 1977-01-10 1978-11-28 Syntex Inc 11**22halophenylthio**44*chlorooorr fluorophenyl**nnbutyl*imidazole process for preparing same and application method thereof
JPS5390263A (en) * 1977-01-19 1978-08-08 Syntex Inc Compound process for preparing same composition containing same and method of inhibiting mould

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