CH636089A5 - Antimicrobial 1-(2-(halophenylthio)-4-(p-chloro- or -fluorophenyl)-n-butyl)imidazoles and their preparation - Google Patents

Antimicrobial 1-(2-(halophenylthio)-4-(p-chloro- or -fluorophenyl)-n-butyl)imidazoles and their preparation Download PDF

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Publication number
CH636089A5
CH636089A5 CH23678A CH23678A CH636089A5 CH 636089 A5 CH636089 A5 CH 636089A5 CH 23678 A CH23678 A CH 23678A CH 23678 A CH23678 A CH 23678A CH 636089 A5 CH636089 A5 CH 636089A5
Authority
CH
Switzerland
Prior art keywords
chlorine
butyl
imidazole
antimicrobial
compounds
Prior art date
Application number
CH23678A
Other languages
German (de)
English (en)
Inventor
Keith A M Walker
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/758,094 external-priority patent/US4078071A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of CH636089A5 publication Critical patent/CH636089A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/501,3-Diazoles; Hydrogenated 1,3-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CH23678A 1977-01-10 1978-01-10 Antimicrobial 1-(2-(halophenylthio)-4-(p-chloro- or -fluorophenyl)-n-butyl)imidazoles and their preparation CH636089A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/758,094 US4078071A (en) 1976-03-08 1977-01-10 Derivatives of substituted N-alkyl imidazoles

Publications (1)

Publication Number Publication Date
CH636089A5 true CH636089A5 (en) 1983-05-13

Family

ID=25050465

Family Applications (1)

Application Number Title Priority Date Filing Date
CH23678A CH636089A5 (en) 1977-01-10 1978-01-10 Antimicrobial 1-(2-(halophenylthio)-4-(p-chloro- or -fluorophenyl)-n-butyl)imidazoles and their preparation

Country Status (10)

Country Link
JP (1) JPS53135976A (fr)
CH (1) CH636089A5 (fr)
DE (1) DE2800755A1 (fr)
FR (1) FR2376850A2 (fr)
GB (1) GB1567431A (fr)
HK (1) HK17681A (fr)
IT (1) IT1111401B (fr)
MY (1) MY8100370A (fr)
NL (1) NL184160C (fr)
SE (1) SE443783B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4213991A (en) * 1978-05-30 1980-07-22 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkyl imidazoles and compositions and methods containing the same
JPS55160767A (en) * 1979-05-31 1980-12-13 Idota Yutaka Imidazole derivative
EP0105575B1 (fr) * 1982-07-12 1987-03-04 G.D. Searle & Co. Composés 1-(1H-imidazolyliques), 1-N-morpholinyliques et pyridyliques, leur préparation et compositions pharmaceutiques les contenant
GB8316444D0 (en) * 1983-06-16 1983-07-20 Ici Plc Heterocycle compounds
HUP0400270A3 (en) * 2004-01-27 2007-09-28 Richter Gedeon Nyrt High purity butoconazole nitrate having a predetermined particle size and process for the production of the same
JP6229896B2 (ja) * 2013-01-21 2017-11-15 国立大学法人大阪大学 フェノキシアルキルアミン化合物
EP3558304A2 (fr) 2016-12-23 2019-10-30 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Inhibiteurs de l'élément 1 de la sous-famille b de la famille 7 du cytochrome p450 (cyp7b1) destinés à être utilisés dans le traitement de maladies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
MX3866E (es) * 1975-07-28 1981-08-26 Syntex Inc Metodo mejorado para preparar derivados de imidazoles n-alquil sustituidos
JPS6028820A (ja) * 1983-07-26 1985-02-14 Daishiro Fujishima 脱酸素剤

Also Published As

Publication number Publication date
NL184160C (nl) 1989-05-01
IT7867025A0 (it) 1978-01-09
NL7800097A (nl) 1978-07-12
IT1111401B (it) 1986-01-13
FR2376850B2 (fr) 1980-02-15
DE2800755C2 (fr) 1989-09-07
SE7800111L (sv) 1978-07-11
HK17681A (en) 1981-05-08
JPS635388B2 (fr) 1988-02-03
SE443783B (sv) 1986-03-10
GB1567431A (en) 1980-05-14
FR2376850A2 (fr) 1978-08-04
DE2800755A1 (de) 1978-07-13
JPS53135976A (en) 1978-11-28
NL184160B (nl) 1988-12-01
MY8100370A (en) 1981-12-31

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SPCR Supplementary protection certificate rejected

Free format text: IKS 47573/860618, IKS 47574/860618, 960125

PL Patent ceased