FR2364457A1 - Procede de stabilisation d'un co-enzyme et d'un enzyme labiles - Google Patents

Procede de stabilisation d'un co-enzyme et d'un enzyme labiles

Info

Publication number
FR2364457A1
FR2364457A1 FR7727386A FR7727386A FR2364457A1 FR 2364457 A1 FR2364457 A1 FR 2364457A1 FR 7727386 A FR7727386 A FR 7727386A FR 7727386 A FR7727386 A FR 7727386A FR 2364457 A1 FR2364457 A1 FR 2364457A1
Authority
FR
France
Prior art keywords
enzyme
labile
stabilized
enzymes
stabilization process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7727386A
Other languages
English (en)
French (fr)
Other versions
FR2364457B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MODROVICH IVAN
Original Assignee
MODROVICH IVAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MODROVICH IVAN filed Critical MODROVICH IVAN
Publication of FR2364457A1 publication Critical patent/FR2364457A1/fr
Application granted granted Critical
Publication of FR2364457B1 publication Critical patent/FR2364457B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FR7727386A 1976-09-13 1977-09-09 Procede de stabilisation d'un co-enzyme et d'un enzyme labiles Granted FR2364457A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72256576A 1976-09-13 1976-09-13

Publications (2)

Publication Number Publication Date
FR2364457A1 true FR2364457A1 (fr) 1978-04-07
FR2364457B1 FR2364457B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-04-25

Family

ID=24902389

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7727386A Granted FR2364457A1 (fr) 1976-09-13 1977-09-09 Procede de stabilisation d'un co-enzyme et d'un enzyme labiles

Country Status (7)

Country Link
JP (2) JPS5843078B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1102225A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH631208A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2740957A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2364457A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1570971A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE446742B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1102225A (en) * 1976-09-13 1981-06-02 Ivan E. Modrovich Stabilized liquid enzyme and coenzyme compositions and method of preparing same
DE2814154A1 (de) * 1978-04-01 1979-10-11 Behringwerke Ag Stabilisierte nicotinamid-nucleotide und verfahren zu ihrer herstellung
JPS5513008A (en) * 1978-07-11 1980-01-29 Mitsui Toatsu Chem Inc Stabilization of aqueous solution of enzyme
CA1187388A (en) * 1978-09-20 1985-05-21 American Monitor Corporation Stabilization of working reagent solutions containing nadh, nadph, and/or enzymes, and the use of such stabilized reagents in enzymes or substrate assays
JPS55138399A (en) * 1979-04-13 1980-10-29 Dainippon Pharmaceut Co Ltd Composition for determining beta-d-galactosidase and method thereof
JPS5982398A (ja) * 1982-11-01 1984-05-12 Toyobo Co Ltd 補酵素の安定化法
JPS62101773A (ja) * 1985-10-29 1987-05-12 白木金属工業株式会社 電子キ−装置
US5298406A (en) * 1992-09-14 1994-03-29 E. I. Du Pont De Nemours And Company Formulation for stabilizing enzymatic activity and immunoreactivity of creatine kinase and creatine kinase isoenzymes
DE10313972A1 (de) * 2003-03-27 2004-10-21 Degussa Ag Gekoppeltes cofaktorabhängiges enzymatisches Reaktionssystem
JP4986281B2 (ja) * 2004-10-05 2012-07-25 旭化成ファーマ株式会社 補酵素の安定化方法およびその組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2308639A1 (fr) * 1975-04-21 1976-11-19 Hoffmann La Roche Solution stable d'un coenzyme
FR2344568A1 (fr) * 1976-03-17 1977-10-14 Modrovich Ivan Procede de stabilisation d'un enzyme labile
FR2344570A1 (fr) * 1976-03-17 1977-10-14 Modrovich Ivan Procede de stabilisation d'un coenzyme labile

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1084079A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-11-30 Beckman Instruments Inc
DE1673194A1 (de) * 1965-07-22 1970-10-29 Dresden Arzneimittel Verfahren und Mittel zur Bestimmung von Transaminase-Aktivitaeten
US3296094A (en) * 1966-05-05 1967-01-03 Baxter Laboratories Inc Stabilized aqueous enzyme solutions
US3557002A (en) * 1967-11-15 1971-01-19 Procter & Gamble Stabilized aqueous enzyme preparation
US3627688A (en) * 1968-11-12 1971-12-14 Procter & Gamble Stabilized aqueous enzyme containing compositions
GB1322951A (en) * 1969-10-29 1973-07-11 Warner Lambert Co Process and agent for the determination of glucose
DE2061984C3 (de) * 1970-12-16 1974-04-11 Boehringer Mannheim Gmbh, 6800 Mannheim Reagens zur Bestimmung der Lactat-Dehydrogenase im Farbtest
DE2302721C2 (de) * 1973-01-19 1975-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung der Creatinkinase
US3920798A (en) * 1973-05-08 1975-11-18 Union Carbide Corp Zeolite y synthesis
US3962037A (en) * 1975-01-30 1976-06-08 Miles Laboratories, Inc. Composition for stabilizing an enzyme-containing reagent
JPS52111183A (en) * 1976-03-12 1977-09-17 Hitachi Ltd Hand rail guiding device
CA1102225A (en) * 1976-09-13 1981-06-02 Ivan E. Modrovich Stabilized liquid enzyme and coenzyme compositions and method of preparing same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2308639A1 (fr) * 1975-04-21 1976-11-19 Hoffmann La Roche Solution stable d'un coenzyme
FR2344568A1 (fr) * 1976-03-17 1977-10-14 Modrovich Ivan Procede de stabilisation d'un enzyme labile
FR2344570A1 (fr) * 1976-03-17 1977-10-14 Modrovich Ivan Procede de stabilisation d'un coenzyme labile

Also Published As

Publication number Publication date
SE446742B (sv) 1986-10-06
JPH0147999B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-10-17
SE7711853L (sv) 1979-04-21
CH631208A5 (en) 1982-07-30
DE2740957A1 (de) 1978-03-16
JPS5352685A (en) 1978-05-13
DE2740957C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-07-30
JPS60105494A (ja) 1985-06-10
FR2364457B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-04-25
GB1570971A (en) 1980-07-09
CA1102225A (en) 1981-06-02
JPS5843078B2 (ja) 1983-09-24

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