FR2361894A2 - Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity - Google Patents

Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity

Info

Publication number
FR2361894A2
FR2361894A2 FR7625051A FR7625051A FR2361894A2 FR 2361894 A2 FR2361894 A2 FR 2361894A2 FR 7625051 A FR7625051 A FR 7625051A FR 7625051 A FR7625051 A FR 7625051A FR 2361894 A2 FR2361894 A2 FR 2361894A2
Authority
FR
France
Prior art keywords
acetamido
thiazolyl
antibacterial activity
hydroxyimino
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7625051A
Other languages
French (fr)
Other versions
FR2361894B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7601834A external-priority patent/FR2346014A1/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7625051A priority Critical patent/FR2361894A2/en
Priority to SE7614678A priority patent/SE440655B/en
Priority to IL51192A priority patent/IL51192A/en
Priority to ES455089A priority patent/ES455089A1/en
Priority to SU772439818A priority patent/SU822754A3/en
Priority to YU137/77A priority patent/YU41060B/en
Priority to AR266241A priority patent/AR231985A1/en
Priority to SI7710137A priority patent/SI7710137A8/en
Priority to MX971377U priority patent/MX7126E/en
Priority to MX775372U priority patent/MX4407E/en
Priority to IT47727/77A priority patent/IT1104601B/en
Priority to DD7700197036A priority patent/DD128594A5/en
Priority to CH78777A priority patent/CH622264A5/en
Priority to JP504977A priority patent/JPS52102293A/en
Priority to DE2760123A priority patent/DE2760123C2/en
Priority to DE2760287A priority patent/DE2760287C2/de
Priority to DK023677A priority patent/DK161082C/en
Priority to GB2640/77A priority patent/GB1580621A/en
Priority to NZ189245A priority patent/NZ189245A/en
Priority to LU76624A priority patent/LU76624A1/xx
Priority to GB15561/79A priority patent/GB1580623A/en
Priority to HU77RO909A priority patent/HU173110B/en
Priority to PT66099A priority patent/PT66099B/en
Priority to BE174311A priority patent/BE850662A/en
Priority to CY1123A priority patent/CY1123A/en
Priority to DE2702501A priority patent/DE2702501C2/en
Priority to DE2759895A priority patent/DE2759895C2/en
Priority to DD7700200629A priority patent/DD132869A5/en
Priority to NZ183150A priority patent/NZ183150A/en
Priority to CA000270375A priority patent/CA1319682C/en
Priority to PL1977195504A priority patent/PL122698B1/en
Priority to GR52630A priority patent/GR70302B/el
Priority to IE2395/81A priority patent/IE45016B1/en
Priority to CS45277A priority patent/CS207575B2/en
Priority to IE148/77A priority patent/IE45015B1/en
Priority to AT41277A priority patent/AT355205B/en
Priority to AU21579/77A priority patent/AU511680B2/en
Priority to NL7700706A priority patent/NL7700706A/en
Priority to BE176189A priority patent/BE852971R/en
Priority to DE19772714747 priority patent/DE2714747A1/en
Priority to GB13839/77A priority patent/GB1580622A/en
Priority to US05/817,114 priority patent/US4152432A/en
Priority to ES466539A priority patent/ES466539A1/en
Priority to LU79216A priority patent/LU79216A1/en
Publication of FR2361894A2 publication Critical patent/FR2361894A2/en
Priority to US05/917,985 priority patent/US4283396A/en
Priority to US05/920,704 priority patent/US4196205A/en
Priority to CS786884A priority patent/CS207577B2/en
Priority to AT0209479A priority patent/AT373592B/en
Priority to IL57445A priority patent/IL57445A0/en
Priority to CH1074579A priority patent/CH621347A5/en
Priority to AU56672/80A priority patent/AU541985B2/en
Application granted granted Critical
Publication of FR2361894B2 publication Critical patent/FR2361894B2/fr
Priority to NLAANVRAGE8003189,A priority patent/NL185208C/en
Priority to CH215181A priority patent/CH628038A5/en
Priority to US06/257,984 priority patent/US4376203A/en
Priority to HK503/81A priority patent/HK50381A/en
Priority to SE8204893A priority patent/SE455307B/en
Priority to YU196782A priority patent/YU44030B/en
Priority to SI8211967A priority patent/SI8211967A8/en
Priority to YU196682A priority patent/YU44031B/en
Priority to SI8211966A priority patent/SI8211966A8/en
Priority to AT357782A priority patent/AT378190B/en
Priority to US06/449,680 priority patent/US4843164A/en
Priority to SI8310011A priority patent/SI8310011A8/en
Priority to YU00012/83A priority patent/YU1283A/en
Priority to YU11/83A priority patent/YU43143B/en
Priority to DK242483A priority patent/DK160872C/en
Priority to KE3365A priority patent/KE3365A/en
Priority to MY417/85A priority patent/MY8500417A/en
Priority to US07/359,870 priority patent/US4988816A/en
Priority to JP2101872A priority patent/JPH03204868A/en
Priority to US07/582,386 priority patent/US5103012A/en
Priority to US07/777,614 priority patent/US5336776A/en
Priority to JP5023427A priority patent/JPH05247013A/en
Priority to GEAP19931537A priority patent/GEP19970783B/en
Priority to HR931341A priority patent/HRP931341B1/en
Priority to HR931343A priority patent/HRP931343B1/en
Priority to HR931342A priority patent/HRP931342B1/en
Priority to MD94-0268A priority patent/MD227C2/en
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms

Abstract

New cephalosporins are of formula (I) In the formula R and R1 are both H or both hydrolysable or hydrogenolysable gps. or R1 can also be opt. substd. 1-4C alkyl, A is H or an equiv. of an alkali(ne earth) metal or an amine. (I) have antibacterial activity against Gram-positive and -negative bacteria, esp. penicillin-resistant Staphylococci, E.coli, Klebsiella, Salmonella and Proteus spp. A typical cpd. is 3-acetoxymethyl-7-(2-(2-tritylamino-4-thiazolyl)-2-tritylhydroxyi- mino-acetamido)-3-cephem-4-carboxylic acid. In an example, this is prepd. starting from ethyl gamma-chloro-alpha-oximinoacetyl-acetate.
FR7625051A 1976-01-23 1976-08-18 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity Granted FR2361894A2 (en)

Priority Applications (78)

Application Number Priority Date Filing Date Title
FR7625051A FR2361894A2 (en) 1976-01-23 1976-08-18 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity
SE7614678A SE440655B (en) 1976-01-23 1976-12-29 SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
IL51192A IL51192A (en) 1976-01-23 1976-12-31 Oxime derivatives of 7-(amino thiazolyl)acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions containing them
ES455089A ES455089A1 (en) 1976-01-23 1977-01-15 Oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
SU772439818A SU822754A3 (en) 1976-01-23 1977-01-18 Method of preparing derivatives of 7-/-2-(2-aminothiazolyl-4)-2-oxyiminoacetamido/3-acetoxymethyl-3-cephem-4-carboxylic acid in the form of sin-isomers
YU137/77A YU41060B (en) 1976-01-23 1977-01-19 Process for obtaining new antibiotics
AR266241A AR231985A1 (en) 1976-01-23 1977-01-19 PROCEDURE FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO ACID TIAZOLIL CEPHALOSPORANIC ACETAMIDE, INTERMEDIARIES AND PROCEDURE FOR THE PREPARATION
SI7710137A SI7710137A8 (en) 1976-01-23 1977-01-19 Process for obtaining new oxim derivatives of 7-amino-thiazolyl- acetamido-cephalosporic acid
MX971377U MX7126E (en) 1976-01-23 1977-01-20 PROCEDURE FOR PREPARING DERIVATIVES OF TIDAZOLYL-IMINOACETIC ACID
MX775372U MX4407E (en) 1976-01-23 1977-01-20 PROCEDURE TO PREPARE OXIMES DERIVED FROM 7-AMINO-TIDAZOLYL-ACETAMIDE-CEPHALOSPORANIC ACID
IT47727/77A IT1104601B (en) 1976-01-23 1977-01-20 PROCEDURE FOR THE PRODUCTION OF OXIME DERIVED FROM 7-AMINOTHIAZOLIACETAMIDOCEPHALOSPORANIC ACID
DD7700197036A DD128594A5 (en) 1976-01-23 1977-01-21 PROCESS FOR THE PREPARATION OF NEW OXIM DERIVATIVES OF 7-AMINOTHIAZOLYLAZETAMIDO-ZEPHALOSPORANSAURE
CH78777A CH622264A5 (en) 1976-01-23 1977-01-21 Process for the preparation of new oximes, syn isomers, derived from 7-(aminothiazolylacetamido)cephalosporanic acid
JP504977A JPS52102293A (en) 1976-01-23 1977-01-21 Novel oxim derivative of 77 aminothiazolylacetoamide cephalospolanate process for preparing same and pharmaceutical composition
DE2760123A DE2760123C2 (en) 1976-01-23 1977-01-21 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them
DE2760287A DE2760287C2 (en) 1976-01-23 1977-01-21
DK023677A DK161082C (en) 1976-01-23 1977-01-21 ANALOGY PROCEDURE FOR PREPARING SYN-ISOMER OXIMER DERIVATIVES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID
GB2640/77A GB1580621A (en) 1976-01-23 1977-01-21 Oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
NZ189245A NZ189245A (en) 1976-01-23 1977-01-21 Substituted 2-(2-amino-4-thiazoyl)-2-hydroxyimino-acetic acid derivatives
LU76624A LU76624A1 (en) 1976-01-23 1977-01-21
GB15561/79A GB1580623A (en) 1976-01-23 1977-01-21 2-(2-amino-4-thiazolyl)-2-hydroxymino-acetic acid and substituted derivatives thereof useful as intermediates in the manufacture of antibiotic oxime derivatives of 7-aminothiazolyl-acetamido-cehalosporanic acid and processes for preparing them
HU77RO909A HU173110B (en) 1976-01-23 1977-01-21 Process for producing oximes of 7-bracket-amino-thiazolyl-acetamido-bracket closed-3-acetoxymethyl-ceph-3-eme-4-carboxylic acid mido-skobka zakryta-3-acetoksimetil-cef-3-em-4-karbonovo
PT66099A PT66099B (en) 1976-01-23 1977-01-21 PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
BE174311A BE850662A (en) 1976-01-23 1977-01-21 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
CY1123A CY1123A (en) 1976-01-23 1977-01-21 Oxime derivatives of 7-aminothiazolylacettamidocephanosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
DE2702501A DE2702501C2 (en) 1976-01-23 1977-01-21 Oxime derivatives of 7-aminothiazolylacetamidocephalosporanic acid (syn isomers), their preparation and pharmaceutical compositions
DE2759895A DE2759895C2 (en) 1976-01-23 1977-01-21 Use of syn-alkoxyimino derivatives of aminothiazolylacetic acids for the preparation of corresponding 7-aminothiazolyl-syn-alkoxyiminoacetamidocephalosporanic acids
DD7700200629A DD132869A5 (en) 1976-01-23 1977-01-21 PROCESS FOR THE PREPARATION OF NEW AMINOTHIAZOLYLAZETAMIDO DERIVATIVES
NZ183150A NZ183150A (en) 1976-01-23 1977-01-21 7-aminothiazolyl-iminoa-cetamido-cephalosporin derivatives and pharmaceutical compositions
CA000270375A CA1319682C (en) 1976-01-23 1977-01-21 Process for the preparation of new oximes derivated from 7-aminothiazolylacetamidocephalosporanic acid
PL1977195504A PL122698B1 (en) 1976-01-23 1977-01-22 Process for preparing novel oximes, derivatives of 7-amino-thazolyl-acetamido-cephalosporanic acid
GR52630A GR70302B (en) 1976-01-23 1977-01-22
IE2395/81A IE45016B1 (en) 1976-01-23 1977-01-24 2-(2-amino-4-thiazolyl)-2-hydroxyiminoacedtic acid and substituted derivatives thereof useful as intermediates in the manufacture of antibiotic oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid, and processes for preparing them
CS45277A CS207575B2 (en) 1976-01-23 1977-01-24 Method of preparation of new oxime derivates of the 7-aminothiazolylacetamidocephalsporan acid
IE148/77A IE45015B1 (en) 1976-01-23 1977-01-24 New oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid, processes for preparing them and pharmaceutical compositions incorporating them
AT41277A AT355205B (en) 1976-01-23 1977-01-24 METHOD FOR PRODUCING NEW OXIMES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID AND THEIR SALTS
AU21579/77A AU511680B2 (en) 1976-01-23 1977-01-24 Oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid
NL7700706A NL7700706A (en) 1976-01-23 1977-01-24 PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINOTHIAZOLYL-ACEETAMIDO CEPHALOSPORANIC ACID.
BE176189A BE852971R (en) 1976-01-23 1977-03-29 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
DE19772714747 DE2714747A1 (en) 1976-01-23 1977-04-01 NEW OXIMES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORIC ACID, MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITIONS AND APPLICATION AS A DRUG
GB13839/77A GB1580622A (en) 1976-01-23 1977-04-01 Oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporanic acid processes for their preparation and pharmaceutical compositions containing them
US05/817,114 US4152432A (en) 1976-01-23 1977-07-19 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
ES466539A ES466539A1 (en) 1976-01-23 1978-02-01 Oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
LU79216A LU79216A1 (en) 1976-01-23 1978-03-10 PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
US05/917,985 US4283396A (en) 1976-01-23 1978-06-22 3-Acetoxymethyl-7-(hydroxyiminoacetamido)-cephalosporanic acid derivatives
US05/920,704 US4196205A (en) 1976-01-23 1978-06-30 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
CS786884A CS207577B2 (en) 1976-01-23 1978-10-23 Method of making the derivatives of the 2-/2-amino-4-thiazolyl/-vinegar acid
AT0209479A AT373592B (en) 1976-01-23 1979-03-20 METHOD FOR PRODUCING NEW 4-THIAZOLYL OXIMES
IL57445A IL57445A0 (en) 1976-01-23 1979-05-31 Novel thiazolyl compounds
CH1074579A CH621347A5 (en) 1976-01-23 1979-12-04 Process for the preparation of substituted 2-(2-amino-4-thiazolyl)acetic acid oximes
AU56672/80A AU541985B2 (en) 1976-01-23 1980-03-20 Derivatives of 2-(-2-amino-4-thiazolyl)-2-imino acetic acid
NLAANVRAGE8003189,A NL185208C (en) 1976-01-23 1980-10-31 PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH ANTIBACTERIAL ACTION BASED ON AN ANTIBIOTIC ACTIVE 7- (2- (2 AMINO-4-THIAZOLYL) ACETAMIDO) CEF-3-EM-4-CARBONIC ACID COMPOUND.
CH215181A CH628038A5 (en) 1976-01-23 1981-03-30 Process for the preparation of syn oximes of substituted 2-(2-amino-4-thiazolyl)acetic acids
US06/257,984 US4376203A (en) 1976-01-23 1981-04-27 Novel 3-acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
HK503/81A HK50381A (en) 1976-01-23 1981-10-22 New oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid,processes for preparing them and pharmaceutical compositions incorporating them
SE8204893A SE455307B (en) 1976-01-23 1982-08-26 2-AMINO-4-THIAZOLYL-OXIIMINO-ETHYAC ACID DERIVATIVES FOR USE AS AN INTERMEDIATE TO THE SIMILAR CEPHALOSPORINE DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF
YU196782A YU44030B (en) 1976-01-23 1982-08-31 Process for obtaining thiazole derivatives
SI8211967A SI8211967A8 (en) 1976-01-23 1982-08-31 Process for preparation of thiazole derivatives
YU196682A YU44031B (en) 1976-01-23 1982-08-31 Process for obtaining thiazole derivatives
SI8211966A SI8211966A8 (en) 1976-01-23 1982-08-31 Process for preparation of thiazole derivatives
AT357782A AT378190B (en) 1976-01-23 1982-09-27 METHOD FOR PRODUCING NEW OXIMES
US06/449,680 US4843164A (en) 1976-01-23 1982-12-14 Aminothiazolyl acetic acid derivatives
SI8310011A SI8310011A8 (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics
YU00012/83A YU1283A (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics
YU11/83A YU43143B (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics
DK242483A DK160872C (en) 1976-01-23 1983-05-30 2-AMINO-4-THIAZOLYL-OXYIMINO ACETIC ACID DERIVATIVES USED AS INTERMEDIATES FOR THE PREPARATION OF SIMILAR CEPHALOSPORINE DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF
KE3365A KE3365A (en) 1976-01-23 1984-01-11 New oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid,processes for preparing them and pharmaceutical compositions incorporating them
MY417/85A MY8500417A (en) 1976-01-23 1985-12-30 New oxime derivatives of 7-amino thiazolyca-cetamido-cephalosporanic acid, processes for preparing them and pharmaceutical compositions incorporating them
US07/359,870 US4988816A (en) 1976-01-23 1989-05-31 Novel 3-acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
JP2101872A JPH03204868A (en) 1976-01-23 1990-04-19 Novel oxime derivative of aminothiazolyl- acetic acid
US07/582,386 US5103012A (en) 1976-01-23 1990-09-13 3-acetoxymethyl-7-(iminoacetamino)-cephalosporanic acid derivatives
US07/777,614 US5336776A (en) 1976-01-23 1991-10-16 3-acetoxymethyl-7-(iminoacetamideo)-cephalosporanic acid
JP5023427A JPH05247013A (en) 1976-01-23 1993-01-20 Novel oxime derivative of aminothiazolyl acetic acid and preparation thereof
GEAP19931537A GEP19970783B (en) 1976-01-23 1993-09-09 Process for the preparation of new oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporin acid
HR931341A HRP931341B1 (en) 1976-01-23 1993-10-29 Process for the preparation of thiazole derivatives
HR931343A HRP931343B1 (en) 1976-01-23 1993-10-29 Process for the preparation of thiazole derivatives
HR931342A HRP931342B1 (en) 1976-01-23 1993-10-29 Process for the preparation of new oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporin acid
MD94-0268A MD227C2 (en) 1976-01-23 1994-09-08 Method of 7-(2-(2-aminothiazolyl-4)-2-oxyiminoacetamido)-3-acetoxymethyl-3-cefem-4-carbonic acid preparation in the form of sin-isomers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (en) 1976-01-23 1976-01-23 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity
FR7625051A FR2361894A2 (en) 1976-01-23 1976-08-18 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity

Publications (2)

Publication Number Publication Date
FR2361894A2 true FR2361894A2 (en) 1978-03-17
FR2361894B2 FR2361894B2 (en) 1980-03-21

Family

ID=26219263

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7625051A Granted FR2361894A2 (en) 1976-01-23 1976-08-18 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity

Country Status (2)

Country Link
CS (1) CS207575B2 (en)
FR (1) FR2361894A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727753A1 (en) * 1976-09-08 1978-03-16 Takeda Chemical Industries Ltd NEW CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THE SAME
FR2445830A1 (en) * 1979-01-05 1980-08-01 Roussel Uclaf 7-Amino-thiazolyl-acetamido-cephalosporin oxime derivs. - are broad spectrum antibacterials useful against penicillin resistant Staphylococci (BE 25.9.78)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727753A1 (en) * 1976-09-08 1978-03-16 Takeda Chemical Industries Ltd NEW CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THE SAME
DE2760448C2 (en) * 1976-09-08 1989-06-22 Takeda Chemical Industries, Ltd., Osaka, Jp
FR2445830A1 (en) * 1979-01-05 1980-08-01 Roussel Uclaf 7-Amino-thiazolyl-acetamido-cephalosporin oxime derivs. - are broad spectrum antibacterials useful against penicillin resistant Staphylococci (BE 25.9.78)

Also Published As

Publication number Publication date
FR2361894B2 (en) 1980-03-21
CS207575B2 (en) 1981-08-31

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