FR2359843A1 - Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics - Google Patents

Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics

Info

Publication number
FR2359843A1
FR2359843A1 FR7723504A FR7723504A FR2359843A1 FR 2359843 A1 FR2359843 A1 FR 2359843A1 FR 7723504 A FR7723504 A FR 7723504A FR 7723504 A FR7723504 A FR 7723504A FR 2359843 A1 FR2359843 A1 FR 2359843A1
Authority
FR
France
Prior art keywords
alkyl
opt
substd
alkenoyl
cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7723504A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762634082 external-priority patent/DE2634082A1/en
Priority claimed from DE19762651395 external-priority patent/DE2651395A1/en
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2359843A1 publication Critical patent/FR2359843A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Cephalosporins of formula (I): (where n = 0 or 1, R1-3 are H or 1-5C alkyl but not 4-5C alkyl when n = 1, R4 is H, opt. substd. alkyl, phthalidyl or a cation, R5 is H or 1-3C alkyl A is H, alkoxy, halogen, or CH2Y, Y is H, acyloxy, alkoxy, opt. substd. pyridinium, opt. substd. carbamoyloxy or SR6, R6 is acyl, alkyl or an opt. substd. 5- or 6-membered heterocycle opt. fused with a 5- or 6-membered aromatic ring) are novel. Cpds. (I) are antibiotics active against Gram-positive and -negative bacteria, including penicillinase-producing Staphylococci. A typical cpd. is 7-(3-butenylamino)-cephalosporanic acid. In an example, this is prepd. from 3-butenoic acid and 7-aminocephalosporanic acid.
FR7723504A 1976-07-29 1977-07-29 Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics Withdrawn FR2359843A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762634082 DE2634082A1 (en) 1976-07-29 1976-07-29 Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics
DE19762651395 DE2651395A1 (en) 1976-11-11 1976-11-11 Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics

Publications (1)

Publication Number Publication Date
FR2359843A1 true FR2359843A1 (en) 1978-02-24

Family

ID=25770753

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7723504A Withdrawn FR2359843A1 (en) 1976-07-29 1977-07-29 Alkenoyl-amido-cephalosporin(s) - for use as broad-spectrum antibiotics

Country Status (5)

Country Link
JP (1) JPS5318598A (en)
ES (1) ES460952A1 (en)
FR (1) FR2359843A1 (en)
IT (1) IT1085475B (en)
NL (1) NL7708177A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379464A (en) * 1981-02-18 1983-04-12 Philip Morris Incorporated Cooked flavors for smoking products
FR2550200B1 (en) * 1983-08-01 1988-04-08 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF CEPHEM COMPOUNDS WITH ANTIMICROBIAL ACTIVITY AND NOVEL PRODUCTS THUS OBTAINED

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099867A (en) * 1996-09-27 1998-04-21 Sony Corp Treatment of waste water
JPH1099767A (en) * 1996-09-25 1998-04-21 Hiroshi Imamura Workpiece fitting hanger

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1099767A (en) * 1996-09-25 1998-04-21 Hiroshi Imamura Workpiece fitting hanger
JPH1099867A (en) * 1996-09-27 1998-04-21 Sony Corp Treatment of waste water

Also Published As

Publication number Publication date
NL7708177A (en) 1978-01-31
IT1085475B (en) 1985-05-28
ES460952A1 (en) 1978-12-01
JPS5318598A (en) 1978-02-20

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Legal Events

Date Code Title Description
ST Notification of lapse