IT1036078B - Beta-Lactam antibiotic combination preparations - contg a 7-tetrazolylacetamido-cephem cpd and penicillin - Google Patents

Beta-Lactam antibiotic combination preparations - contg a 7-tetrazolylacetamido-cephem cpd and penicillin

Info

Publication number
IT1036078B
IT1036078B IT6748475A IT6748475A IT1036078B IT 1036078 B IT1036078 B IT 1036078B IT 6748475 A IT6748475 A IT 6748475A IT 6748475 A IT6748475 A IT 6748475A IT 1036078 B IT1036078 B IT 1036078B
Authority
IT
Italy
Prior art keywords
cpd
cephem
tetrazolylacetamido
contg
penicillin
Prior art date
Application number
IT6748475A
Other languages
Italian (it)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of IT1036078B publication Critical patent/IT1036078B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Antibiotically active pharmaceutical combination prepns. contain (A) a 7-titrazolylacetamide-cephem cpd. of formula (I) (where R1 is an opt. substd. heterocyclic group), e.g. cefazolin, or a salt thereof and (B) a pencillin cpd. of formula (II) (where R2 is an acyl group), e.g. carbenicillin, cloxacillin or dichoxacillin, or a salt thereof. (I) and (II) act synergistically, so that the combination is highly active against pathogenic bacteria (esp. Gram-negative bacteria such as Citrobacter and Proteus) against which (I) or (II) along have little or no activity. Dosage for humans is e.g. ca 2-10g (adults)or ca 20-40 mg/kg (children) per day by injection. For the treatment of borine mastitis, a dosage of ca 200 mg/quarter can be used.
IT6748475A 1974-03-27 1975-02-25 Beta-Lactam antibiotic combination preparations - contg a 7-tetrazolylacetamido-cephem cpd and penicillin IT1036078B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3500874A JPS5813526B2 (en) 1974-03-27 1974-03-27 Grasshopper's garden

Publications (1)

Publication Number Publication Date
IT1036078B true IT1036078B (en) 1979-10-30

Family

ID=12430047

Family Applications (1)

Application Number Title Priority Date Filing Date
IT6748475A IT1036078B (en) 1974-03-27 1975-02-25 Beta-Lactam antibiotic combination preparations - contg a 7-tetrazolylacetamido-cephem cpd and penicillin

Country Status (4)

Country Link
JP (1) JPS5813526B2 (en)
CA (1) CA1038759A (en)
DK (1) DK132675A (en)
IT (1) IT1036078B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54126735A (en) * 1978-03-24 1979-10-02 Toyama Chem Co Ltd Bactericidal composition for medical use
JPS59126251U (en) * 1983-02-15 1984-08-25 ミノルタ株式会社 Copy machine
JPS6036646U (en) * 1983-08-22 1985-03-13 京セラミタ株式会社 Shell type electrostatic copying machine
JPH0582374U (en) * 1992-04-08 1993-11-09 元実 原田 Clothes cover

Also Published As

Publication number Publication date
JPS50126816A (en) 1975-10-06
JPS5813526B2 (en) 1983-03-14
DK132675A (en) 1975-09-28
CA1038759A (en) 1978-09-19

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