FR2219775A1 - Isoxazolylacetamido penicillanic and cephalosporanic acids - partic. active against Gram-positive bacteria - Google Patents

Isoxazolylacetamido penicillanic and cephalosporanic acids - partic. active against Gram-positive bacteria

Info

Publication number
FR2219775A1
FR2219775A1 FR7407098A FR7407098A FR2219775A1 FR 2219775 A1 FR2219775 A1 FR 2219775A1 FR 7407098 A FR7407098 A FR 7407098A FR 7407098 A FR7407098 A FR 7407098A FR 2219775 A1 FR2219775 A1 FR 2219775A1
Authority
FR
France
Prior art keywords
active against
against gram
isoxazolylacetamido
penicillanic
partic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7407098A
Other languages
French (fr)
Other versions
FR2219775B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1018973A external-priority patent/GB1464377A/en
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of FR2219775A1 publication Critical patent/FR2219775A1/en
Application granted granted Critical
Publication of FR2219775B1 publication Critical patent/FR2219775B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivatives of formula (I) (where Q is a group of formula (II), (III) or (IV) in which X is H, OH, lower alkanoyloxy or the residue of a nucleophilic agent and E is H, a salt-forming cation or a pharmaceutically tolerable ester residue; R is OH, OCH3 Cl or Br; R1 is H, Cl or Br; and R2 is H, Cl, Br, amino, lower alkoxycarbonylamino, phenyl(lower alkoxy)carbonylamino, p-nitro- or p-methoxyphenyl(lower alkoxy)carbonylamino, a sulphonic acid group or its alkali(ne earth) metal or amine salt, or a carbamoyl group) are antibiotics particularly active against gram-positive organisms. They also have good activity against penicillin-resistant staphylococci and gram-negative organisms (Pasteurella multocida, Klebsiella pneumoniae, Salmonella Dublin). They can thus be used as medicinal agents; they may also be used as growth promoters for ruminants.
FR7407098A 1973-03-02 1974-03-01 Isoxazolylacetamido penicillanic and cephalosporanic acids - partic. active against Gram-positive bacteria Granted FR2219775A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1018973A GB1464377A (en) 1973-03-02 1973-03-02 Penicillanic and cephalosporanic acid derivatives
GB183674 1974-01-15

Publications (2)

Publication Number Publication Date
FR2219775A1 true FR2219775A1 (en) 1974-09-27
FR2219775B1 FR2219775B1 (en) 1978-07-28

Family

ID=26237021

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7407098A Granted FR2219775A1 (en) 1973-03-02 1974-03-01 Isoxazolylacetamido penicillanic and cephalosporanic acids - partic. active against Gram-positive bacteria

Country Status (6)

Country Link
JP (1) JPS5029591A (en)
AU (1) AU6620274A (en)
DE (1) DE2409949A1 (en)
ES (2) ES423827A1 (en)
FR (1) FR2219775A1 (en)
NL (1) NL7402778A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2591598A1 (en) * 1985-07-16 1987-06-19 Biogal Gyogyszergyar New ceph-3-em-4-carboxylic acid derivatives, their preparation and medicaments containing them

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54106495A (en) * 1978-02-09 1979-08-21 Dai Ichi Seiyaku Co Ltd Cephem derivative
JPS6052713B2 (en) * 1978-04-11 1985-11-20 三共株式会社 7-Methoxycephalosporin compound, its production method, and antibacterial agent containing the compound as a main ingredient
JPS6017368A (en) * 1983-07-09 1985-01-29 Toyota Motor Corp Method and device for detecting short circuit of kickless cable

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2112504A1 (en) * 1970-11-06 1972-06-16 Koninklijke Gist Spiritus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2112504A1 (en) * 1970-11-06 1972-06-16 Koninklijke Gist Spiritus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2591598A1 (en) * 1985-07-16 1987-06-19 Biogal Gyogyszergyar New ceph-3-em-4-carboxylic acid derivatives, their preparation and medicaments containing them

Also Published As

Publication number Publication date
NL7402778A (en) 1974-09-04
JPS5029591A (en) 1975-03-25
ES423827A1 (en) 1976-10-16
DE2409949A1 (en) 1974-09-05
AU6620274A (en) 1975-09-04
FR2219775B1 (en) 1978-07-28
ES423828A1 (en) 1977-06-16

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Legal Events

Date Code Title Description
ST Notification of lapse