FR2361388A1 - 2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique - Google Patents

2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique

Info

Publication number
FR2361388A1
FR2361388A1 FR7709583A FR7709583A FR2361388A1 FR 2361388 A1 FR2361388 A1 FR 2361388A1 FR 7709583 A FR7709583 A FR 7709583A FR 7709583 A FR7709583 A FR 7709583A FR 2361388 A1 FR2361388 A1 FR 2361388A1
Authority
FR
France
Prior art keywords
thienyl
ketone
dimethyl
pyridyl
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7709583A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Publication of FR2361388A1 publication Critical patent/FR2361388A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C2300/00—Application independent of particular apparatuses
    • F16C2300/10—Application independent of particular apparatuses related to size
    • F16C2300/14—Large applications, e.g. bearings having an inner diameter exceeding 500 mm

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

2-thiényl-(4,5-diméthyl-2-pyridyl)cétone et son procédé de préparation. On fait réagir du 2-cyano-4,5-diméthylpyridine avec une solution éthérée de thiényllithium, et par hydrolyse acide on obtient la 2-thiényl-(4,5-diméthyl-2-pyridino)cétone. Applications pharmaceutiques comme analgésiques.
FR7709583A 1975-09-19 1977-03-30 2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique Withdrawn FR2361388A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES441097A ES441097A1 (es) 1975-09-19 1975-09-19 Procedimiento para la obtencion de 2,4, 5-trimetil-tieno (3,2-f) morfano.

Publications (1)

Publication Number Publication Date
FR2361388A1 true FR2361388A1 (fr) 1978-03-10

Family

ID=8470007

Family Applications (5)

Application Number Title Priority Date Filing Date
FR7627080A Withdrawn FR2362128A1 (fr) 1975-09-19 1976-09-09 2-cyano-4,5-dimethyl-pyridine, et procede de preparation
FR7709582A Withdrawn FR2361397A1 (fr) 1975-09-19 1977-03-30 2,4,5 trimethyl-thieno(3,2-f)morphane, procede de preparation et application pharmacologique
FR7709583A Withdrawn FR2361388A1 (fr) 1975-09-19 1977-03-30 2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique
FR7709585A Withdrawn FR2361390A1 (fr) 1975-09-19 1977-03-30 2-2 thenyl-1,4,5 trimethyl-1,2,3,6-tetrahydropyridine a application therapeutique comme analgesique
FR7709584A Withdrawn FR2361389A1 (fr) 1975-09-19 1977-03-30 2-(2-thenyl)-4,5-dimethylpyridine a application therapeutique comme analgesique

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FR7627080A Withdrawn FR2362128A1 (fr) 1975-09-19 1976-09-09 2-cyano-4,5-dimethyl-pyridine, et procede de preparation
FR7709582A Withdrawn FR2361397A1 (fr) 1975-09-19 1977-03-30 2,4,5 trimethyl-thieno(3,2-f)morphane, procede de preparation et application pharmacologique

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7709585A Withdrawn FR2361390A1 (fr) 1975-09-19 1977-03-30 2-2 thenyl-1,4,5 trimethyl-1,2,3,6-tetrahydropyridine a application therapeutique comme analgesique
FR7709584A Withdrawn FR2361389A1 (fr) 1975-09-19 1977-03-30 2-(2-thenyl)-4,5-dimethylpyridine a application therapeutique comme analgesique

Country Status (15)

Country Link
JP (1) JPS5248694A (fr)
AR (1) AR210612A1 (fr)
AT (1) AT347051B (fr)
BE (1) BE845755A (fr)
CA (1) CA1068279A (fr)
CH (1) CH617195A5 (fr)
DE (1) DE2639181C3 (fr)
ES (1) ES441097A1 (fr)
FR (5) FR2362128A1 (fr)
GB (1) GB1513980A (fr)
NL (1) NL7610437A (fr)
NZ (1) NZ181870A (fr)
PT (1) PT65547B (fr)
SE (2) SE7609357L (fr)
SU (3) SU620210A3 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1274913A (fr) * 1959-09-09 1961-11-03 Rohm & Haas Procédé de cyanuration de composés nu-hétérocycliques et nitriles ainsi obtenus

Also Published As

Publication number Publication date
ES441097A1 (es) 1977-03-16
PT65547A (en) 1976-10-01
SU620210A3 (ru) 1978-08-15
DE2639181A1 (de) 1977-03-31
FR2361389A1 (fr) 1978-03-10
JPS5248694A (en) 1977-04-18
NL7610437A (nl) 1977-03-22
DE2639181C3 (de) 1979-05-31
FR2361397A1 (fr) 1978-03-10
SU671731A3 (ru) 1979-06-30
DE2639181B2 (de) 1978-10-05
ATA687976A (de) 1978-04-15
AU1715576A (en) 1978-03-02
FR2361390A1 (fr) 1978-03-10
GB1513980A (en) 1978-06-14
SE7609357L (sv) 1977-03-20
NZ181870A (en) 1978-11-13
PT65547B (en) 1978-03-24
BE845755A (fr) 1977-03-01
CA1068279A (fr) 1979-12-18
AR210612A1 (es) 1977-08-31
SE7907106L (sv) 1979-08-27
FR2362128A1 (fr) 1978-03-17
CH617195A5 (en) 1980-05-14
SU650506A3 (ru) 1979-02-28
AT347051B (de) 1978-12-11

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Legal Events

Date Code Title Description
ST Notification of lapse