FR2362128A1 - 2-cyano-4,5-dimethyl-pyridine, et procede de preparation - Google Patents

2-cyano-4,5-dimethyl-pyridine, et procede de preparation

Info

Publication number
FR2362128A1
FR2362128A1 FR7627080A FR7627080A FR2362128A1 FR 2362128 A1 FR2362128 A1 FR 2362128A1 FR 7627080 A FR7627080 A FR 7627080A FR 7627080 A FR7627080 A FR 7627080A FR 2362128 A1 FR2362128 A1 FR 2362128A1
Authority
FR
France
Prior art keywords
dimethyl
cyano
pyridine
preparation
degrees
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7627080A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Publication of FR2362128A1 publication Critical patent/FR2362128A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16CSHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C2300/00Application independent of particular apparatuses
    • F16C2300/10Application independent of particular apparatuses related to size
    • F16C2300/14Large applications, e.g. bearings having an inner diameter exceeding 500 mm

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Procédé de préparation de 2-cyano-4,5-diméthyl-pyridine. On fait réagir le N-oxyde de 3,4-lutidine sur le sulfate de diméthyle pour obtenir le méthylsulfate de 1-méthoxy-3,4 diméthylpyridinium, puis on traite celui-ci sous atmosphère inerte pendant 24 heures entre 0 degrés et 5 degrés C par une solution de cyanure alcalin pour obtenir le composé :
FR7627080A 1975-09-19 1976-09-09 2-cyano-4,5-dimethyl-pyridine, et procede de preparation Withdrawn FR2362128A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES441097A ES441097A1 (es) 1975-09-19 1975-09-19 Procedimiento para la obtencion de 2,4, 5-trimetil-tieno (3,2-f) morfano.

Publications (1)

Publication Number Publication Date
FR2362128A1 true FR2362128A1 (fr) 1978-03-17

Family

ID=8470007

Family Applications (5)

Application Number Title Priority Date Filing Date
FR7627080A Withdrawn FR2362128A1 (fr) 1975-09-19 1976-09-09 2-cyano-4,5-dimethyl-pyridine, et procede de preparation
FR7709584A Withdrawn FR2361389A1 (fr) 1975-09-19 1977-03-30 2-(2-thenyl)-4,5-dimethylpyridine a application therapeutique comme analgesique
FR7709585A Withdrawn FR2361390A1 (fr) 1975-09-19 1977-03-30 2-2 thenyl-1,4,5 trimethyl-1,2,3,6-tetrahydropyridine a application therapeutique comme analgesique
FR7709582A Withdrawn FR2361397A1 (fr) 1975-09-19 1977-03-30 2,4,5 trimethyl-thieno(3,2-f)morphane, procede de preparation et application pharmacologique
FR7709583A Withdrawn FR2361388A1 (fr) 1975-09-19 1977-03-30 2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique

Family Applications After (4)

Application Number Title Priority Date Filing Date
FR7709584A Withdrawn FR2361389A1 (fr) 1975-09-19 1977-03-30 2-(2-thenyl)-4,5-dimethylpyridine a application therapeutique comme analgesique
FR7709585A Withdrawn FR2361390A1 (fr) 1975-09-19 1977-03-30 2-2 thenyl-1,4,5 trimethyl-1,2,3,6-tetrahydropyridine a application therapeutique comme analgesique
FR7709582A Withdrawn FR2361397A1 (fr) 1975-09-19 1977-03-30 2,4,5 trimethyl-thieno(3,2-f)morphane, procede de preparation et application pharmacologique
FR7709583A Withdrawn FR2361388A1 (fr) 1975-09-19 1977-03-30 2-thienyl-(4,5-dimethyl-2-pyridyl)-cetone a application therapeutique comme analgesique

Country Status (15)

Country Link
JP (1) JPS5248694A (fr)
AR (1) AR210612A1 (fr)
AT (1) AT347051B (fr)
BE (1) BE845755A (fr)
CA (1) CA1068279A (fr)
CH (1) CH617195A5 (fr)
DE (1) DE2639181C3 (fr)
ES (1) ES441097A1 (fr)
FR (5) FR2362128A1 (fr)
GB (1) GB1513980A (fr)
NL (1) NL7610437A (fr)
NZ (1) NZ181870A (fr)
PT (1) PT65547B (fr)
SE (2) SE7609357L (fr)
SU (3) SU620210A3 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1274913A (fr) * 1959-09-09 1961-11-03 Rohm & Haas Procédé de cyanuration de composés nu-hétérocycliques et nitriles ainsi obtenus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1274913A (fr) * 1959-09-09 1961-11-03 Rohm & Haas Procédé de cyanuration de composés nu-hétérocycliques et nitriles ainsi obtenus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV499/78 *

Also Published As

Publication number Publication date
CA1068279A (fr) 1979-12-18
DE2639181C3 (de) 1979-05-31
SU650506A3 (ru) 1979-02-28
SU671731A3 (ru) 1979-06-30
AT347051B (de) 1978-12-11
BE845755A (fr) 1977-03-01
FR2361390A1 (fr) 1978-03-10
PT65547A (en) 1976-10-01
ES441097A1 (es) 1977-03-16
FR2361388A1 (fr) 1978-03-10
GB1513980A (en) 1978-06-14
DE2639181A1 (de) 1977-03-31
CH617195A5 (en) 1980-05-14
FR2361389A1 (fr) 1978-03-10
AR210612A1 (es) 1977-08-31
SE7609357L (sv) 1977-03-20
ATA687976A (de) 1978-04-15
AU1715576A (en) 1978-03-02
SU620210A3 (ru) 1978-08-15
DE2639181B2 (de) 1978-10-05
JPS5248694A (en) 1977-04-18
NL7610437A (nl) 1977-03-22
SE7907106L (sv) 1979-08-27
FR2361397A1 (fr) 1978-03-10
PT65547B (en) 1978-03-24
NZ181870A (en) 1978-11-13

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Legal Events

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