FR2285866A1 - N or-o-cycloalkyl dehydro-13,14 prostaglandines et procede de leur preparation - Google Patents
N or-o-cycloalkyl dehydro-13,14 prostaglandines et procede de leur preparationInfo
- Publication number
- FR2285866A1 FR2285866A1 FR7527034A FR7527034A FR2285866A1 FR 2285866 A1 FR2285866 A1 FR 2285866A1 FR 7527034 A FR7527034 A FR 7527034A FR 7527034 A FR7527034 A FR 7527034A FR 2285866 A1 FR2285866 A1 FR 2285866A1
- Authority
- FR
- France
- Prior art keywords
- dehydro
- prostaglandins
- cycloalkyl
- preparation
- cycloalkyl dehydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4018—Esters of cycloaliphatic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT27654/74A IT1053781B (it) | 1974-09-25 | 1974-09-25 | Omega nor cicloalcil 13.14 deidro prostaglandine |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2285866A1 true FR2285866A1 (fr) | 1976-04-23 |
FR2285866B1 FR2285866B1 (fr) | 1978-12-22 |
Family
ID=11222055
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7527034A Granted FR2285866A1 (fr) | 1974-09-25 | 1975-09-03 | N or-o-cycloalkyl dehydro-13,14 prostaglandines et procede de leur preparation |
FR7808815A Granted FR2378757A1 (fr) | 1974-09-25 | 1978-03-24 | Nor-o-heterocyclo-dehydro-13, 14 prostaglandines, leur procede de preparation et leur application comme medicaments |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7808815A Granted FR2378757A1 (fr) | 1974-09-25 | 1978-03-24 | Nor-o-heterocyclo-dehydro-13, 14 prostaglandines, leur procede de preparation et leur application comme medicaments |
Country Status (24)
Country | Link |
---|---|
US (2) | US4035415A (fr) |
JP (2) | JPS5839156B2 (fr) |
AT (1) | AT351184B (fr) |
BE (1) | BE832983A (fr) |
CA (1) | CA1083569A (fr) |
CH (1) | CH617186A5 (fr) |
CS (1) | CS191276B2 (fr) |
CY (1) | CY954A (fr) |
DE (1) | DE2539116C2 (fr) |
DK (1) | DK155316C (fr) |
FI (1) | FI63932C (fr) |
FR (2) | FR2285866A1 (fr) |
GB (1) | GB1483880A (fr) |
HK (1) | HK42478A (fr) |
HU (1) | HU174287B (fr) |
IL (1) | IL48043A (fr) |
IT (1) | IT1053781B (fr) |
KE (1) | KE2851A (fr) |
MY (1) | MY7800321A (fr) |
NL (1) | NL187354C (fr) |
NO (1) | NO146357C (fr) |
SE (1) | SE422057B (fr) |
SU (1) | SU652889A3 (fr) |
ZA (1) | ZA755420B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2372820A1 (fr) * | 1976-12-02 | 1978-06-30 | Schering Ag | Procede de preparation de derives d'alcenyl-6 oxa-2 bicyclo (3-3-0) octanones-3, intermediaires pour la preparation de prostaglandines |
WO1992002495A1 (fr) * | 1990-07-27 | 1992-02-20 | Schering Aktiengesellschaft Berlin/Bergkamen | Derives de cyclopentane, procede pour leur fabrication, ainsi que leur utilisation pharmaceutique |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU501803B2 (en) * | 1975-03-21 | 1979-06-28 | Farmitalia Carlo Erba S.P.A. | Fluoro-prostaglandins |
IT1088966B (it) * | 1977-11-15 | 1985-06-10 | Erba Carlo Spa | 13,14-dideidro-prostaglandine |
CH656877A5 (de) * | 1981-11-27 | 1986-07-31 | Erba Farmitalia | Optisch aktive oder racemische prostaglandinderivate. |
ATE101342T1 (de) * | 1988-09-06 | 1994-02-15 | Kabi Pharmacia Ab | Prostaglandinderivate zur behandlung des gruenen stars oder einer okularen hypertension. |
US5741810A (en) * | 1996-02-29 | 1998-04-21 | Allergan | Cyclopentane heptan(ene)oic acid, 2- heteroarylalkenyl derivatives as therapeutic agents |
CZ2013987A3 (cs) * | 2013-12-10 | 2015-06-17 | Univerzita Pardubice | Způsob přípravy (3aR,4S,5R,6aS)-4-[(3S)-5-cyklohexyl-3-hydroxypent-1-yn-1-yl]-5-(ethoxymethoxy)-hexahydro-2H-cyklopenta[b]furan-2-onu |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3843713A (en) * | 1972-04-05 | 1974-10-22 | Ciba Geigy Corp | 16-lower alkoxy lower alkyl,-16-20 w-pentano,pge |
GB1425961A (en) * | 1972-04-13 | 1976-02-25 | Erba Carlo Spa | Prostanoic acid derivatives |
US3876690A (en) * | 1973-05-11 | 1975-04-08 | American Cyanamid Co | 1-alkoxy-9-keto-prostenoic acid derivatives |
US3884909A (en) * | 1973-09-24 | 1975-05-20 | Standard Brands Inc | Gelatinizable crosslinked cationic starch and method for its manufacture |
HU176654B (en) * | 1974-09-06 | 1981-04-28 | Erba Farmitalia | Process for producing pgf beta-prostaglandines |
FI71138C (fi) * | 1976-12-31 | 1986-11-24 | Erba Farmitalia | Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner |
-
1974
- 1974-09-25 IT IT27654/74A patent/IT1053781B/it active Protection Beyond IP Right Term
-
1975
- 1975-08-06 GB GB32897/75A patent/GB1483880A/en not_active Expired
- 1975-08-06 CY CY954A patent/CY954A/xx unknown
- 1975-08-08 US US05/603,015 patent/US4035415A/en not_active Expired - Lifetime
- 1975-08-25 AT AT656075A patent/AT351184B/de active
- 1975-08-25 JP JP50102845A patent/JPS5839156B2/ja not_active Expired
- 1975-08-25 ZA ZA755420A patent/ZA755420B/xx unknown
- 1975-08-29 DK DK390975A patent/DK155316C/da not_active IP Right Cessation
- 1975-09-02 BE BE159667A patent/BE832983A/fr not_active IP Right Cessation
- 1975-09-02 CS CS755964A patent/CS191276B2/cs unknown
- 1975-09-03 IL IL48043A patent/IL48043A/xx unknown
- 1975-09-03 HU HU75EA152A patent/HU174287B/hu unknown
- 1975-09-03 FR FR7527034A patent/FR2285866A1/fr active Granted
- 1975-09-03 SE SE7509764A patent/SE422057B/xx not_active IP Right Cessation
- 1975-09-03 NO NO753028A patent/NO146357C/no unknown
- 1975-09-03 DE DE2539116A patent/DE2539116C2/de not_active Expired
- 1975-09-04 SU SU752170657A patent/SU652889A3/ru active
- 1975-09-04 NL NLAANVRAGE7510452,A patent/NL187354C/xx not_active IP Right Cessation
- 1975-09-04 CH CH1149575A patent/CH617186A5/de not_active IP Right Cessation
- 1975-09-04 FI FI752491A patent/FI63932C/fi not_active IP Right Cessation
- 1975-09-04 CA CA234,796A patent/CA1083569A/fr not_active Expired
-
1978
- 1978-03-24 FR FR7808815A patent/FR2378757A1/fr active Granted
- 1978-06-27 KE KE2851A patent/KE2851A/xx unknown
- 1978-08-03 HK HK424/78A patent/HK42478A/xx unknown
- 1978-12-30 MY MY321/78A patent/MY7800321A/xx unknown
-
1979
- 1979-02-02 US US06/009,091 patent/US4361577A/en not_active Expired - Lifetime
-
1982
- 1982-09-16 JP JP57159690A patent/JPS5918391B2/ja not_active Expired
Non-Patent Citations (1)
Title |
---|
NEANT * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2372820A1 (fr) * | 1976-12-02 | 1978-06-30 | Schering Ag | Procede de preparation de derives d'alcenyl-6 oxa-2 bicyclo (3-3-0) octanones-3, intermediaires pour la preparation de prostaglandines |
WO1992002495A1 (fr) * | 1990-07-27 | 1992-02-20 | Schering Aktiengesellschaft Berlin/Bergkamen | Derives de cyclopentane, procede pour leur fabrication, ainsi que leur utilisation pharmaceutique |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
TP | Transmission of property | ||
CC | Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990) |
Free format text: 92C0138, 920430 |
|
CB | Supplementary protection certificate (spc) granted (law of 25 june 1990) |
Free format text: 92C0138, 750903 |
|
CL | Concession to grant licences |