ZA755420B - W-nor-cycloalkyl-13, 14-dehydroprostaglandins and process for their preparation - Google Patents

W-nor-cycloalkyl-13, 14-dehydroprostaglandins and process for their preparation

Info

Publication number
ZA755420B
ZA755420B ZA755420A ZA755420A ZA755420B ZA 755420 B ZA755420 B ZA 755420B ZA 755420 A ZA755420 A ZA 755420A ZA 755420 A ZA755420 A ZA 755420A ZA 755420 B ZA755420 B ZA 755420B
Authority
ZA
South Africa
Prior art keywords
dehydroprostaglandins
cycloalkyl
preparation
Prior art date
Application number
ZA755420A
Other languages
English (en)
Inventor
C Gandolfi
R Pellegata
R Ceserani
M Usardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA755420B publication Critical patent/ZA755420B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5407Acyclic saturated phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564Three-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
ZA755420A 1974-09-25 1975-08-25 W-nor-cycloalkyl-13, 14-dehydroprostaglandins and process for their preparation ZA755420B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT27654/74A IT1053781B (it) 1974-09-25 1974-09-25 Omega nor cicloalcil 13.14 deidro prostaglandine

Publications (1)

Publication Number Publication Date
ZA755420B true ZA755420B (en) 1977-04-27

Family

ID=11222055

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA755420A ZA755420B (en) 1974-09-25 1975-08-25 W-nor-cycloalkyl-13, 14-dehydroprostaglandins and process for their preparation

Country Status (24)

Country Link
US (2) US4035415A (xx)
JP (2) JPS5839156B2 (xx)
AT (1) AT351184B (xx)
BE (1) BE832983A (xx)
CA (1) CA1083569A (xx)
CH (1) CH617186A5 (xx)
CS (1) CS191276B2 (xx)
CY (1) CY954A (xx)
DE (1) DE2539116C2 (xx)
DK (1) DK155316C (xx)
FI (1) FI63932C (xx)
FR (2) FR2285866A1 (xx)
GB (1) GB1483880A (xx)
HK (1) HK42478A (xx)
HU (1) HU174287B (xx)
IL (1) IL48043A (xx)
IT (1) IT1053781B (xx)
KE (1) KE2851A (xx)
MY (1) MY7800321A (xx)
NL (1) NL187354C (xx)
NO (1) NO146357C (xx)
SE (1) SE422057B (xx)
SU (1) SU652889A3 (xx)
ZA (1) ZA755420B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU501803B2 (en) * 1975-03-21 1979-06-28 Farmitalia Carlo Erba S.P.A. Fluoro-prostaglandins
DE2655004C3 (de) * 1976-12-02 1980-06-19 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von bicyclischen Laktonen
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4543353A (en) * 1981-11-27 1985-09-24 Farmitalia Carlo Erba S.P.A. Ester and amide derivatives of 13,14-didehydro prostaglandins
JP2721414B2 (ja) * 1988-09-06 1998-03-04 フアーマシア・アンド・アツプジヨン・アー・ベー 縁内障または眼圧亢進の治療のためのプロスタグランジン誘導体
DE4024347A1 (de) * 1990-07-27 1992-01-30 Schering Ag Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
US5741810A (en) * 1996-02-29 1998-04-21 Allergan Cyclopentane heptan(ene)oic acid, 2- heteroarylalkenyl derivatives as therapeutic agents
CZ2013987A3 (cs) * 2013-12-10 2015-06-17 Univerzita Pardubice Způsob přípravy (3aR,4S,5R,6aS)-4-[(3S)-5-cyklohexyl-3-hydroxypent-1-yn-1-yl]-5-(ethoxymethoxy)-hexahydro-2H-cyklopenta[b]furan-2-onu

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3843713A (en) * 1972-04-05 1974-10-22 Ciba Geigy Corp 16-lower alkoxy lower alkyl,-16-20 w-pentano,pge
GB1425962A (en) * 1972-04-13 1976-02-25 Erba Carlo Spa Lactols and lactones
US3876690A (en) * 1973-05-11 1975-04-08 American Cyanamid Co 1-alkoxy-9-keto-prostenoic acid derivatives
US3884909A (en) * 1973-09-24 1975-05-20 Standard Brands Inc Gelatinizable crosslinked cationic starch and method for its manufacture
IT1044796B (it) * 1974-09-06 1980-04-21 Erba Carlo Spa Pgf beta gandolfi
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner

Also Published As

Publication number Publication date
DE2539116A1 (de) 1976-04-08
HK42478A (en) 1978-08-11
JPS58135858A (ja) 1983-08-12
FR2285866A1 (fr) 1976-04-23
MY7800321A (en) 1978-12-31
KE2851A (en) 1978-07-21
JPS5839156B2 (ja) 1983-08-27
DE2539116C2 (de) 1984-08-02
NL7510452A (nl) 1976-03-29
IT1053781B (it) 1981-10-10
CS191276B2 (en) 1979-06-29
SE7509764L (sv) 1976-03-26
IL48043A (en) 1979-12-30
US4361577A (en) 1982-11-30
AT351184B (de) 1979-07-10
DK155316C (da) 1989-08-14
SE422057B (sv) 1982-02-15
NO146357B (no) 1982-06-07
FI752491A (xx) 1976-03-26
IL48043A0 (en) 1975-11-25
SU652889A3 (ru) 1979-03-15
CA1083569A (en) 1980-08-12
AU8381075A (en) 1977-02-10
BE832983A (fr) 1976-03-02
JPS5918391B2 (ja) 1984-04-26
US4035415A (en) 1977-07-12
FI63932C (fi) 1983-09-12
DK155316B (da) 1989-03-28
FR2378757A1 (fr) 1978-08-25
NL187354C (nl) 1991-09-02
JPS51125044A (en) 1976-11-01
CH617186A5 (xx) 1980-05-14
NO146357C (no) 1982-09-15
GB1483880A (en) 1977-08-24
NO753028L (xx) 1976-03-26
FR2285866B1 (xx) 1978-12-22
HU174287B (hu) 1979-12-28
FR2378757B1 (xx) 1980-07-04
FI63932B (fi) 1983-05-31
CY954A (en) 1978-12-22
DK390975A (da) 1976-03-26
ATA656075A (de) 1978-12-15

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