FR2262966A1 - Nouveau benzamide hétérocyclique et son procédé de fabrication - Google Patents
Nouveau benzamide hétérocyclique et son procédé de fabricationInfo
- Publication number
- FR2262966A1 FR2262966A1 FR7407535A FR7407535A FR2262966A1 FR 2262966 A1 FR2262966 A1 FR 2262966A1 FR 7407535 A FR7407535 A FR 7407535A FR 7407535 A FR7407535 A FR 7407535A FR 2262966 A1 FR2262966 A1 FR 2262966A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- opt
- manufacturing process
- new heterocyclic
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 2
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 229940054066 benzamide antipsychotics Drugs 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (69)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH279775A CH605793A5 (fr) | 1974-03-05 | 1974-03-05 | Procédé de préparation de nouveaux N-(1benzylpyrrollidinil 2-alkyl) benzamides substitués |
FR7407535A FR2262966A1 (fr) | 1974-03-05 | 1974-03-05 | Nouveau benzamide hétérocyclique et son procédé de fabrication |
IN338/CAL/75A IN140141B (en, 2012) | 1974-03-05 | 1975-02-21 | |
IL46695A IL46695A (en) | 1974-03-05 | 1975-02-24 | Substituted n-(1-benzylpyrrolidinyl-2-alkyl)-benzamides, their preparation and pharmaceutical compositions containing them |
IL46696A IL46696A (en) | 1974-03-05 | 1975-02-24 | Substituted n-(2-pyrrolidinylalkyl)benzamides, their preparation and pharmaceutical compositions containing them |
ZA00751149A ZA751149B (en) | 1974-03-05 | 1975-02-25 | New n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation |
DE2508045A DE2508045C2 (de) | 1974-03-05 | 1975-02-25 | Substituierte n-(1-benzylpyrrolidinyl-2-alkyl)-benzamide, verfahren zu deren herstellung und diese enthaltende arzneimittel |
ZA00751148A ZA751148B (en) | 1974-03-05 | 1975-02-25 | New n-(1-benzylpyrrolidinyl 2-alkyl) substituted benzamides, their derivatives and its process of preparation |
DE19752507989 DE2507989A1 (de) | 1974-03-05 | 1975-02-25 | N-(2-pyrrolidinylalkyl)-substituierte benzamide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
GB809475A GB1466646A (en) | 1974-03-05 | 1975-02-26 | Substituted benzamides |
GB809575A GB1466822A (en) | 1974-03-05 | 1975-02-26 | Substituted benzamides |
BE1006491A BE826110A (fr) | 1974-03-05 | 1975-02-28 | Nouveaux n-(i-benzylpyrrolidinyl 2-alkyl) benzamides substitues, leur derives, leur procede de preparation |
BE1006490A BE826109A (fr) | 1974-03-05 | 1975-02-28 | Nouveaux n-(2-pyrrolidinyl alkyl) benzamides substitues, leurs derives et leur procede de preparation |
AU78688/75A AU483186B2 (en) | 1974-03-05 | 1975-02-28 | New n-(1-benzylpyrrolidinyl 2 alkyl substituted benzamides, theer derivatives and its process of preparation |
LU71948A LU71948A1 (en, 2012) | 1974-03-05 | 1975-03-03 | |
AU78740/75A AU483111B2 (en) | 1975-03-03 | New-n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation | |
AT160775A AT358570B (de) | 1974-03-05 | 1975-03-03 | Verfahren zur herstellung neuer n-(2- pyrrolidinylalkyl)-substituierter benzamide, ihrer saeureadditionssalze, quartaeren ammonium- salze, optisch aktiven isomeren und deren gemischen |
SE7502341A SE411753B (sv) | 1974-03-05 | 1975-03-03 | Forfarande for framstellning av terapeutiskt aktiva nya derivat av n-(1-bensylpyrrolidinyl-2-alkyl)-bensamid |
EG109/75A EG12577A (en) | 1974-03-05 | 1975-03-03 | Process for preparing of new n-(2-pyrrolidinyl alkyl)substituted benzamides their derivatives and its process of preparation |
SE7502342A SE411754B (sv) | 1974-03-05 | 1975-03-03 | Forfarande for framstellning av terapeutiskt aktiva nya derivat av n-(2-pyrrolidinylalkyl)-bensamid |
EG108/75A EG11971A (en) | 1974-03-05 | 1975-03-03 | New n-(1-benzylpyrrolidinyl 2-alkyl)substituted benzamides,their derivatives and its process of preparation |
AT160675A AT350546B (de) | 1974-03-05 | 1975-03-03 | Verfahren zur herstellung neuer n-(1- benzylpyrrolidinyl-2-alkyl)-benzamide, ihrer saeureadditionssalze, quartaeren ammoniumsalze und der optischen isomeren |
LU71949A LU71949A1 (fr) | 1974-03-05 | 1975-03-03 | Nouveaux N-(l-benzylpyrrolidinyl 2-alkyl) benzamides substitués, leurs dérivés, leur procédé de préparation. |
CA221,240A CA1047504A (en) | 1974-03-05 | 1975-03-04 | N-(2-pyrrolidinyl alkyl) substitutes and derivatives thereof |
CS751444A CS189691B2 (en) | 1974-03-05 | 1975-03-04 | Method of producing novel substituted derivatives of n-1-benzylpyrrolidinyl-2-alkyl/benzamide,salts and isomers thereof |
FI750619A FI58494C (fi) | 1974-03-05 | 1975-03-04 | Menetelmä uusien terapeuttisesti käyttökelpoisten N-(1'-bentsyylipyrrolidin-2'-yylimetyyli) bentsamidien valmistamiseksi |
BG029147A BG25072A3 (bg) | 1974-03-05 | 1975-03-04 | Метод за получаване на n-(1-бензилпиролидинил-2-алкил) субституирани бензамиди |
BG029148A BG24666A3 (bg) | 1974-03-05 | 1975-03-04 | Метод за получаване на n-(2-пиролидинил-алкил)субституирани бензамиди и техните производни |
HUSO1137A HU170637B (en, 2012) | 1974-03-05 | 1975-03-04 | |
SU2112487A SU609464A1 (ru) | 1974-03-05 | 1975-03-04 | Способ получения производных -/2-пирролидинилметил/ бензамидов или их солей |
ES435274A ES435274A1 (es) | 1974-03-05 | 1975-03-04 | Procedimiento de preparacion de n-(2-pirrolidinilalcohil)- benzamidas sustituidas. |
IE456/75A IE40860B1 (en) | 1974-03-05 | 1975-03-04 | Substituted benzamides |
NO750713A NO750713L (en, 2012) | 1974-03-05 | 1975-03-04 | |
OA55430A OA04966A (fr) | 1974-03-05 | 1975-03-04 | Nouveaux N-(2-pyrrolidinyl alkyl) benzamides substitués, leurs dérivés, et leur procédé de préparation. |
FI750620A FI750620A7 (en, 2012) | 1974-03-05 | 1975-03-04 | |
DK86875A DK145376C (da) | 1974-03-05 | 1975-03-04 | Analogifremgangsmaade til fremstilling af n-(1'-benzyl-2'-pyrrolidinylmethyl)-benzamider eller syreadditionssalte,kvaternaere ammoniumsalte eller optisk aktive isomere deraf |
NO750714A NO144740C (no) | 1974-03-05 | 1975-03-04 | Analogifremgangsmaate ved fremstilling av nye, terapeutisk virksomme, substituerte n-(1-benzyl-pyrrolidinyl-2-alkyl)-benzamider |
IN406/CAL/75A IN138587B (en, 2012) | 1974-03-05 | 1975-03-04 | |
YU00517/75A YU51775A (en) | 1974-03-05 | 1975-03-04 | Process for obtaining new n-(1-benzylpyrrolidinyl-2-alkyl)benzamide substituted compounds |
DK86975A DK145377C (da) | 1974-03-05 | 1975-03-04 | Analogifremgangsmaade til fremstilling af n-(2'-pyrrolidinylmethyl)benzamider eller syreadditionssalte eller kvaternaere ammoniumsalte eller optisk aktive isomere deraf |
CA221,237A CA1060029A (en) | 1974-03-05 | 1975-03-04 | N-(1-benzylpyrrolldinyl 2-alkyl) substituted benzamides and derivatives thereof |
CS751445A CS189692B2 (en) | 1974-03-05 | 1975-03-04 | Method of producing novel substituted derivatives of n-/2-pyrrolidinylalkyl/-benzamide,salts and isomers thereof |
IE457/75A IE40818B1 (en) | 1974-03-05 | 1975-03-04 | Substituted benzamides |
SU752109846A SU602116A3 (ru) | 1974-03-05 | 1975-03-04 | Способ получени замещенных (1-бензилпирролидинил-2-алкил)бензамидов или их кислых или аммонийных солей или их правовращающих или левовращающих изомеров |
ES435273A ES435273A1 (es) | 1974-03-05 | 1975-03-04 | Un procedimiento de preparacion de n-(1-bencil-pirrolidi- nil-2-alcohil) -benzamidas sustituidas. |
OA55431A OA04967A (fr) | 1974-03-05 | 1975-03-04 | Nouveaux N-(l-benzylpyrrolidinyl 2-alkyl) benzamides substitués, leurs dérivés, leur procédé de préparation. |
YU516/75A YU40629B (en) | 1974-03-05 | 1975-03-04 | Process for obtaining n-(2-pyrrolidinyl-methyl)-2-methoxy-subst benzamides |
MW12/75A MW1275A1 (en) | 1974-03-05 | 1975-03-05 | New n-(1-benzylpyrrolidinyl 2-alkyl) substituted benzamides, their derivatives and its process of preparation |
MW11/75A MW1175A1 (en) | 1974-03-05 | 1975-03-05 | New n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation |
US05/555,376 US4029673A (en) | 1974-03-05 | 1975-03-05 | N-(1-benzyl pyrrolidinyl 2-alkyl) substituted benzamides and derivatives thereof |
RO7588831A RO70647A (ro) | 1974-03-05 | 1975-03-05 | Procedeu de prepararea a benzamidelor n-(2'-pirolidinilmetil) substituite |
RO7581557A RO73247A (ro) | 1974-03-05 | 1975-03-05 | Procedeu de preparare a benzamidelor substituite |
PL1975178532A PL96942B1 (pl) | 1974-03-05 | 1975-03-05 | Sposob wytwarzania nowych podstawionych n-/1-benzylopirodidynylo-2-alkilo/benzoamidow |
JP50027573A JPS6015616B2 (ja) | 1974-03-05 | 1975-03-05 | N−2−(ピロリジニルメチル)置換ベンズアミド誘導体またはその塩類の製造法 |
CH279975A CH605794A5 (fr) | 1974-03-05 | 1975-03-05 | Procédé de préparation de nouveaux N-(2-pyrrolidinylalkyl)benzamides substitués |
RO7581558A RO72844A (ro) | 1974-03-05 | 1975-03-05 | Procedeu de preparare a benzamidelor n-(2-pirolidinilmetil) substituite |
JP50027572A JPS6058750B2 (ja) | 1974-03-05 | 1975-03-05 | N−(1−ベンジルピロリジニル−2−メチル)置換ベンズアミド誘導体またはその塩類の製造法 |
PL1975178533A PL97091B1 (pl) | 1974-03-05 | 1975-03-05 | Sposob wytwarzania nowych podstawionych n-/2-pirolidynyloalkilo/benzamidow |
NL7502608A NL7502608A (nl) | 1974-03-05 | 1975-03-05 | Werkwijze voor de bereiding van gesubstitueerde benzamiden, van de farmacolo- gisch aanvaardbare zuur-additiezouten ervan, de quaternaire ammoniumzouten ervan en van de rechtsdraaiende en linksdraaiende isomeren er- van, werkwijze voor de bereiding van genees- middelen, alsmede de gevormde geneesmiddelen. |
HU75SO00001139A HU172091B (hu) | 1974-03-05 | 1975-03-05 | Sposob poluchenija proizvodnykh n-skobka-1-benzil-pirrolidinil-2-alkil-skobka zakryta-benzamida |
NLAANVRAGE7502607,A NL184617C (nl) | 1974-03-05 | 1975-03-05 | Werkwijze voor de bereiding van een preparaat met farmacologische werking op basis van benzamidomethylpyrrolidine-derivaten, alsmede werkwijze voor de bereiding van de hierbij toe te passen benzamidomethylpyrrolidine-derivaten. |
DD184578A DD117451A5 (en, 2012) | 1974-03-05 | 1975-03-05 | |
DD184579A DD119420A5 (en, 2012) | 1974-03-05 | 1975-03-05 | |
AR257837A AR206621A1 (es) | 1974-03-05 | 1975-04-04 | Procedimiento para la preparacion de n-(2-pirrolidinilalquil)-benzamidas substituidas |
AR257836A AR212960A1 (es) | 1974-03-05 | 1975-04-04 | Procedimiento para preparar n-(1-bencilpirrolidinil-2-alquil)benzaminas sustituidas |
PH20152A PH14197A (en) | 1974-03-05 | 1977-08-22 | N-(2-pyrrolidinyl alkyl)substituted benzamides and their derivatives |
PH20622A PH14207A (en) | 1974-03-05 | 1978-01-05 | N-(1-benzylpyrrolidinyl 2-alkyl)substituted benzamides |
HK140/78A HK14078A (en) | 1974-03-05 | 1978-03-16 | Substituted benzamides |
HK139/78A HK13978A (en) | 1974-03-05 | 1978-03-16 | Substituted benzamides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7407535A FR2262966A1 (fr) | 1974-03-05 | 1974-03-05 | Nouveau benzamide hétérocyclique et son procédé de fabrication |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2262966A1 true FR2262966A1 (fr) | 1975-10-03 |
FR2262966B1 FR2262966B1 (en, 2012) | 1977-11-04 |
Family
ID=9135893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7407535A Granted FR2262966A1 (fr) | 1974-03-05 | 1974-03-05 | Nouveau benzamide hétérocyclique et son procédé de fabrication |
Country Status (5)
Country | Link |
---|---|
BE (2) | BE826110A (en, 2012) |
FR (1) | FR2262966A1 (en, 2012) |
IN (2) | IN140141B (en, 2012) |
MW (2) | MW1275A1 (en, 2012) |
ZA (2) | ZA751148B (en, 2012) |
-
1974
- 1974-03-05 FR FR7407535A patent/FR2262966A1/fr active Granted
-
1975
- 1975-02-21 IN IN338/CAL/75A patent/IN140141B/en unknown
- 1975-02-25 ZA ZA00751148A patent/ZA751148B/en unknown
- 1975-02-25 ZA ZA00751149A patent/ZA751149B/en unknown
- 1975-02-28 BE BE1006491A patent/BE826110A/fr not_active IP Right Cessation
- 1975-02-28 BE BE1006490A patent/BE826109A/fr not_active IP Right Cessation
- 1975-03-04 IN IN406/CAL/75A patent/IN138587B/en unknown
- 1975-03-05 MW MW12/75A patent/MW1275A1/xx unknown
- 1975-03-05 MW MW11/75A patent/MW1175A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MW1175A1 (en) | 1976-09-08 |
BE826109A (fr) | 1975-08-28 |
IN138587B (en, 2012) | 1976-02-28 |
ZA751149B (en) | 1976-02-25 |
ZA751148B (en) | 1976-02-25 |
IN140141B (en, 2012) | 1976-09-18 |
MW1275A1 (en) | 1976-09-08 |
BE826110A (fr) | 1975-08-28 |
FR2262966B1 (en, 2012) | 1977-11-04 |
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