FR2262966A1 - N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity - Google Patents

N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity

Info

Publication number
FR2262966A1
FR2262966A1 FR7407535A FR7407535A FR2262966A1 FR 2262966 A1 FR2262966 A1 FR 2262966A1 FR 7407535 A FR7407535 A FR 7407535A FR 7407535 A FR7407535 A FR 7407535A FR 2262966 A1 FR2262966 A1 FR 2262966A1
Authority
FR
France
Prior art keywords
alkyl
azacycloalkyl
antiemetic
antiulcer
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7407535A
Other languages
English (en)
Other versions
FR2262966B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ILE DE FRANCE ETUDES SCIENTIFIQU FR
Original Assignee
ILE DE FRANCE ETUDES SCIENTIFIQU FR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ILE DE FRANCE ETUDES SCIENTIFIQU FR filed Critical ILE DE FRANCE ETUDES SCIENTIFIQU FR
Priority to FR7407535A priority Critical patent/FR2262966A1/fr
Priority to CH279775A priority patent/CH605793A5/xx
Priority to IN338/CAL/75A priority patent/IN140141B/en
Priority to IL46696A priority patent/IL46696A/xx
Priority to IL46695A priority patent/IL46695A/xx
Priority to ZA00751148A priority patent/ZA751148B/xx
Priority to DE2508045A priority patent/DE2508045C2/de
Priority to DE19752507989 priority patent/DE2507989A1/de
Priority to ZA00751149A priority patent/ZA751149B/xx
Priority to GB809575A priority patent/GB1466822A/en
Priority to GB809475A priority patent/GB1466646A/en
Priority to BE1006490A priority patent/BE826109A/fr
Priority to BE1006491A priority patent/BE826110A/fr
Priority to AU78688/75A priority patent/AU483186B2/en
Priority to LU71948A priority patent/LU71948A1/xx
Priority to EG108/75A priority patent/EG11971A/xx
Priority to LU71949A priority patent/LU71949A1/xx
Priority to SE7502341A priority patent/SE411753B/xx
Priority to SE7502342A priority patent/SE411754B/xx
Priority to AT160675A priority patent/AT350546B/de
Priority to AU78740/75A priority patent/AU483111B2/en
Priority to EG109/75A priority patent/EG12577A/xx
Priority to AT160775A priority patent/AT358570B/de
Priority to CA221,240A priority patent/CA1047504A/fr
Priority to YU51675A priority patent/YU40629B/xx
Priority to IE456/75A priority patent/IE40860B1/xx
Priority to IN406/CAL/75A priority patent/IN138587B/en
Priority to OA55430A priority patent/OA04966A/fr
Priority to HUSO1137A priority patent/HU170637B/hu
Priority to OA55431A priority patent/OA04967A/fr
Priority to YU00517/75A priority patent/YU51775A/xx
Priority to CS751445A priority patent/CS189692B2/cs
Priority to FI750620A priority patent/FI750620A/fi
Priority to DK86975A priority patent/DK145377C/da
Priority to ES435274A priority patent/ES435274A1/es
Priority to DK86875A priority patent/DK145376C/da
Priority to BG029147A priority patent/BG25072A3/xx
Priority to SU752109846A priority patent/SU602116A3/ru
Priority to NO750713A priority patent/NO750713L/no
Priority to CA221,237A priority patent/CA1060029A/fr
Priority to SU2112487A priority patent/SU609464A3/ru
Priority to CS751444A priority patent/CS189691B2/cs
Priority to NO750714A priority patent/NO144740C/no
Priority to BG029148A priority patent/BG24666A3/xx
Priority to IE457/75A priority patent/IE40818B1/xx
Priority to ES435273A priority patent/ES435273A1/es
Priority to FI750619A priority patent/FI58494C/fi
Priority to DD184579A priority patent/DD119420A5/xx
Priority to JP50027573A priority patent/JPS6015616B2/ja
Priority to RO7581557A priority patent/RO73247A/fr
Priority to MW12/75A priority patent/MW1275A1/xx
Priority to RO7581558A priority patent/RO72844A/fr
Priority to JP50027572A priority patent/JPS6058750B2/ja
Priority to NLAANVRAGE7502607,A priority patent/NL184617C/xx
Priority to RO7588831A priority patent/RO70647A/fr
Priority to PL1975178532A priority patent/PL96942B1/pl
Priority to US05/555,376 priority patent/US4029673A/en
Priority to MW11/75A priority patent/MW1175A1/xx
Priority to DD184578A priority patent/DD117451A5/xx
Priority to NL7502608A priority patent/NL7502608A/xx
Priority to CH279975A priority patent/CH605794A5/xx
Priority to PL1975178533A priority patent/PL97091B1/pl
Priority to HU75SO00001139A priority patent/HU172091B/hu
Priority to AR257836A priority patent/AR212960A1/es
Priority to AR257837A priority patent/AR206621A1/es
Publication of FR2262966A1 publication Critical patent/FR2262966A1/fr
Priority to PH20152A priority patent/PH14197A/en
Application granted granted Critical
Publication of FR2262966B1 publication Critical patent/FR2262966B1/fr
Priority to PH20622A priority patent/PH14207A/en
Priority to HK140/78A priority patent/HK14078A/xx
Priority to HK139/78A priority patent/HK13978A/xx
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7407535A 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity Granted FR2262966A1 (en)

Priority Applications (69)

Application Number Priority Date Filing Date Title
FR7407535A FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity
CH279775A CH605793A5 (fr) 1974-03-05 1974-03-05
IN338/CAL/75A IN140141B (fr) 1974-03-05 1975-02-21
IL46696A IL46696A (en) 1974-03-05 1975-02-24 Substituted n-(2-pyrrolidinylalkyl)benzamides, their preparation and pharmaceutical compositions containing them
IL46695A IL46695A (en) 1974-03-05 1975-02-24 Substituted n-(1-benzylpyrrolidinyl-2-alkyl)-benzamides, their preparation and pharmaceutical compositions containing them
ZA00751148A ZA751148B (en) 1974-03-05 1975-02-25 New n-(1-benzylpyrrolidinyl 2-alkyl) substituted benzamides, their derivatives and its process of preparation
DE2508045A DE2508045C2 (de) 1974-03-05 1975-02-25 N-(1'-Benzylpyrrolidinyl-2'-methyl)-2-methoxybenzamid-Derivate, Verfahren zur ihrer Herstellung und diese enthaltende Arzneimittel
DE19752507989 DE2507989A1 (de) 1974-03-05 1975-02-25 N-(2-pyrrolidinylalkyl)-substituierte benzamide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
ZA00751149A ZA751149B (en) 1974-03-05 1975-02-25 New n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation
GB809575A GB1466822A (en) 1974-03-05 1975-02-26 Substituted benzamides
GB809475A GB1466646A (en) 1974-03-05 1975-02-26 Substituted benzamides
BE1006490A BE826109A (fr) 1974-03-05 1975-02-28 Nouveaux n-(2-pyrrolidinyl alkyl) benzamides substitues, leurs derives et leur procede de preparation
BE1006491A BE826110A (fr) 1974-03-05 1975-02-28 Nouveaux n-(i-benzylpyrrolidinyl 2-alkyl) benzamides substitues, leur derives, leur procede de preparation
AU78688/75A AU483186B2 (en) 1974-03-05 1975-02-28 New n-(1-benzylpyrrolidinyl 2 alkyl substituted benzamides, theer derivatives and its process of preparation
LU71948A LU71948A1 (fr) 1974-03-05 1975-03-03
EG108/75A EG11971A (en) 1974-03-05 1975-03-03 New n-(1-benzylpyrrolidinyl 2-alkyl)substituted benzamides,their derivatives and its process of preparation
LU71949A LU71949A1 (fr) 1974-03-05 1975-03-03
SE7502341A SE411753B (sv) 1974-03-05 1975-03-03 Forfarande for framstellning av terapeutiskt aktiva nya derivat av n-(1-bensylpyrrolidinyl-2-alkyl)-bensamid
SE7502342A SE411754B (sv) 1974-03-05 1975-03-03 Forfarande for framstellning av terapeutiskt aktiva nya derivat av n-(2-pyrrolidinylalkyl)-bensamid
AT160675A AT350546B (de) 1974-03-05 1975-03-03 Verfahren zur herstellung neuer n-(1- benzylpyrrolidinyl-2-alkyl)-benzamide, ihrer saeureadditionssalze, quartaeren ammoniumsalze und der optischen isomeren
AU78740/75A AU483111B2 (en) 1975-03-03 New-n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation
EG109/75A EG12577A (en) 1974-03-05 1975-03-03 Process for preparing of new n-(2-pyrrolidinyl alkyl)substituted benzamides their derivatives and its process of preparation
AT160775A AT358570B (de) 1974-03-05 1975-03-03 Verfahren zur herstellung neuer n-(2- pyrrolidinylalkyl)-substituierter benzamide, ihrer saeureadditionssalze, quartaeren ammonium- salze, optisch aktiven isomeren und deren gemischen
CA221,240A CA1047504A (fr) 1974-03-05 1975-03-04 Derives des produits de substitution de n-(pyrrolidinyl-2 alkyle)
YU51675A YU40629B (en) 1974-03-05 1975-03-04 Process for obtaining n-(2-pyrrolidinyl-methyl)-2-methoxy-subst benzamides
IE456/75A IE40860B1 (en) 1974-03-05 1975-03-04 Substituted benzamides
IN406/CAL/75A IN138587B (fr) 1974-03-05 1975-03-04
OA55430A OA04966A (fr) 1974-03-05 1975-03-04 Nouveaux N-(2-pyrrolidinyl alkyl) benzamides substitués, leurs dérivés, et leur procédé de préparation.
HUSO1137A HU170637B (fr) 1974-03-05 1975-03-04
OA55431A OA04967A (fr) 1974-03-05 1975-03-04 Nouveaux N-(l-benzylpyrrolidinyl 2-alkyl) benzamides substitués, leurs dérivés, leur procédé de préparation.
YU00517/75A YU51775A (en) 1974-03-05 1975-03-04 Process for obtaining new n-(1-benzylpyrrolidinyl-2-alkyl)benzamide substituted compounds
CS751445A CS189692B2 (en) 1974-03-05 1975-03-04 Method of producing novel substituted derivatives of n-/2-pyrrolidinylalkyl/-benzamide,salts and isomers thereof
FI750620A FI750620A (fr) 1974-03-05 1975-03-04
DK86975A DK145377C (da) 1974-03-05 1975-03-04 Analogifremgangsmaade til fremstilling af n-(2'-pyrrolidinylmethyl)benzamider eller syreadditionssalte eller kvaternaere ammoniumsalte eller optisk aktive isomere deraf
ES435274A ES435274A1 (es) 1974-03-05 1975-03-04 Procedimiento de preparacion de n-(2-pirrolidinilalcohil)- benzamidas sustituidas.
DK86875A DK145376C (da) 1974-03-05 1975-03-04 Analogifremgangsmaade til fremstilling af n-(1'-benzyl-2'-pyrrolidinylmethyl)-benzamider eller syreadditionssalte,kvaternaere ammoniumsalte eller optisk aktive isomere deraf
BG029147A BG25072A3 (en) 1974-03-05 1975-03-04 A method of obtaining n-(1-benzylpyrolidinyl-2-alkyl)substituted benzamides
SU752109846A SU602116A3 (ru) 1974-03-05 1975-03-04 Способ получени замещенных (1-бензилпирролидинил-2-алкил)бензамидов или их кислых или аммонийных солей или их правовращающих или левовращающих изомеров
NO750713A NO750713L (fr) 1974-03-05 1975-03-04
CA221,237A CA1060029A (fr) 1974-03-05 1975-03-04 Benzamides de type n-(1-benzylpyrrolldinyl 2-alkyl) substituees et leurs derives
SU2112487A SU609464A3 (ru) 1974-03-05 1975-03-04 Способ получени производных -/2-пирролидинилметил/ бензамидов или их солей
CS751444A CS189691B2 (en) 1974-03-05 1975-03-04 Method of producing novel substituted derivatives of n-1-benzylpyrrolidinyl-2-alkyl/benzamide,salts and isomers thereof
NO750714A NO144740C (no) 1974-03-05 1975-03-04 Analogifremgangsmaate ved fremstilling av nye, terapeutisk virksomme, substituerte n-(1-benzyl-pyrrolidinyl-2-alkyl)-benzamider
BG029148A BG24666A3 (en) 1974-03-05 1975-03-04 Method of preparing n-(2-pyrrolidinyl-alkyl) sub tituted benzamides and derivatives thereof
IE457/75A IE40818B1 (en) 1974-03-05 1975-03-04 Substituted benzamides
ES435273A ES435273A1 (es) 1974-03-05 1975-03-04 Un procedimiento de preparacion de n-(1-bencil-pirrolidi- nil-2-alcohil) -benzamidas sustituidas.
FI750619A FI58494C (fi) 1974-03-05 1975-03-04 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-(1'-bensylpyrrolidin-2'-ylmetyl)bensamider
DD184579A DD119420A5 (fr) 1974-03-05 1975-03-05
JP50027573A JPS6015616B2 (ja) 1974-03-05 1975-03-05 Ｎ−２−（ピロリジニルメチル）置換ベンズアミド誘導体またはその塩類の製造法
RO7581557A RO73247A (fr) 1974-03-05 1975-03-05 Procede de preparation des benzamides substitus
MW12/75A MW1275A1 (en) 1974-03-05 1975-03-05 New n-(1-benzylpyrrolidinyl 2-alkyl) substituted benzamides, their derivatives and its process of preparation
RO7581558A RO72844A (fr) 1974-03-05 1975-03-05 Procede pour la preparation des benzamides n-(2-pyrolidinylmethyle) substitus
JP50027572A JPS6058750B2 (ja) 1974-03-05 1975-03-05 Ｎ−（１−ベンジルピロリジニル−２−メチル）置換ベンズアミド誘導体またはその塩類の製造法
NLAANVRAGE7502607,A NL184617C (nl) 1974-03-05 1975-03-05 Werkwijze voor de bereiding van een preparaat met farmacologische werking op basis van benzamidomethylpyrrolidine-derivaten, alsmede werkwijze voor de bereiding van de hierbij toe te passen benzamidomethylpyrrolidine-derivaten.
RO7588831A RO70647A (fr) 1974-03-05 1975-03-05 Procede pour la preparation des n-(2'-pyrolidynille)-2-methoxy-benzamides substituees
PL1975178532A PL96942B1 (pl) 1974-03-05 1975-03-05 Sposob wytwarzania nowych podstawionych n-/1-benzylopirodidynylo-2-alkilo/benzoamidow
US05/555,376 US4029673A (en) 1974-03-05 1975-03-05 N-(1-benzyl pyrrolidinyl 2-alkyl) substituted benzamides and derivatives thereof
MW11/75A MW1175A1 (en) 1974-03-05 1975-03-05 New n-(2-pyrrolidinyl alkyl) substituted benzamides, their derivatives and its process of preparation
DD184578A DD117451A5 (fr) 1974-03-05 1975-03-05
NL7502608A NL7502608A (nl) 1974-03-05 1975-03-05 Werkwijze voor de bereiding van gesubstitueerde benzamiden, van de farmacolo- gisch aanvaardbare zuur-additiezouten ervan, de quaternaire ammoniumzouten ervan en van de rechtsdraaiende en linksdraaiende isomeren er- van, werkwijze voor de bereiding van genees- middelen, alsmede de gevormde geneesmiddelen.
CH279975A CH605794A5 (fr) 1974-03-05 1975-03-05
PL1975178533A PL97091B1 (pl) 1974-03-05 1975-03-05 Sposob wytwarzania nowych podstawionych n-/2-pirolidynyloalkilo/benzamidow
HU75SO00001139A HU172091B (hu) 1974-03-05 1975-03-05 Sposob poluchenija proizvodnykh n-skobka-1-benzil-pirrolidinil-2-alkil-skobka zakryta-benzamida
AR257836A AR212960A1 (es) 1974-03-05 1975-04-04 Procedimiento para preparar n-(1-bencilpirrolidinil-2-alquil)benzaminas sustituidas
AR257837A AR206621A1 (es) 1974-03-05 1975-04-04 Procedimiento para la preparacion de n-(2-pirrolidinilalquil)-benzamidas substituidas
PH20152A PH14197A (en) 1974-03-05 1977-08-22 N-(2-pyrrolidinyl alkyl)substituted benzamides and their derivatives
PH20622A PH14207A (en) 1974-03-05 1978-01-05 N-(1-benzylpyrrolidinyl 2-alkyl)substituted benzamides
HK140/78A HK14078A (en) 1974-03-05 1978-03-16 Substituted benzamides
HK139/78A HK13978A (en) 1974-03-05 1978-03-16 Substituted benzamides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7407535A FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity

Publications (2)

Publication Number Publication Date
FR2262966A1 true FR2262966A1 (en) 1975-10-03
FR2262966B1 FR2262966B1 (fr) 1977-11-04

Family

ID=9135893

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7407535A Granted FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity

Country Status (5)

Country Link
BE (2) BE826110A (fr)
FR (1) FR2262966A1 (fr)
IN (2) IN140141B (fr)
MW (2) MW1275A1 (fr)
ZA (2) ZA751149B (fr)

Also Published As

Publication number Publication date
MW1275A1 (en) 1976-09-08
BE826110A (fr) 1975-08-28
ZA751149B (en) 1976-02-25
FR2262966B1 (fr) 1977-11-04
ZA751148B (en) 1976-02-25
IN140141B (fr) 1976-09-18
MW1175A1 (en) 1976-09-08
BE826109A (fr) 1975-08-28
IN138587B (fr) 1976-02-28

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