FR2107917A1 - - Google Patents

Info

Publication number
FR2107917A1
FR2107917A1 FR7131866A FR7131866A FR2107917A1 FR 2107917 A1 FR2107917 A1 FR 2107917A1 FR 7131866 A FR7131866 A FR 7131866A FR 7131866 A FR7131866 A FR 7131866A FR 2107917 A1 FR2107917 A1 FR 2107917A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7131866A
Other languages
French (fr)
Other versions
FR2107917B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH359870A external-priority patent/CH533639A/de
Priority claimed from CH1412070A external-priority patent/CH537404A/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2107917A1 publication Critical patent/FR2107917A1/fr
Application granted granted Critical
Publication of FR2107917B1 publication Critical patent/FR2107917B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C07D333/80—Seven-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
FR7131866A 1970-03-11 1971-09-03 Expired FR2107917B1 (enExample)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH359870A CH533639A (de) 1970-03-11 1970-03-11 Verfahren zur Herstellung neuer Benzo(4,5)cyclohepta(1,2-b)-thiophen-Derivate
CH1159370A CH531000A (de) 1970-03-11 1970-07-31 Verfahren zur Herstellung neuer Benzocycloheptathiophene
CH1412070A CH537404A (de) 1970-09-24 1970-09-24 Verfahren zur Herstellung neuer Thiophenderivate
CH163271 1971-02-04

Publications (2)

Publication Number Publication Date
FR2107917A1 true FR2107917A1 (enExample) 1972-05-12
FR2107917B1 FR2107917B1 (enExample) 1975-04-18

Family

ID=27428249

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7107901A Expired FR2085695B1 (enExample) 1970-03-11 1971-03-08
FR7131866A Expired FR2107917B1 (enExample) 1970-03-11 1971-09-03

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7107901A Expired FR2085695B1 (enExample) 1970-03-11 1971-03-08

Country Status (12)

Country Link
US (4) US3682930A (enExample)
AT (2) AT319238B (enExample)
BE (2) BE764019A (enExample)
CA (2) CA960673A (enExample)
CH (1) CH531000A (enExample)
DE (2) DE2111071C3 (enExample)
FR (2) FR2085695B1 (enExample)
GB (4) GB1355537A (enExample)
LU (2) LU62757A1 (enExample)
NL (2) NL167431C (enExample)
OA (2) OA03692A (enExample)
SE (2) SE368954B (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene
US3960894A (en) * 1972-01-24 1976-06-01 Sandoz Ltd. 9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones
BE794377A (fr) * 1972-01-24 1973-07-23 Sandoz Sa Nouveaux derives du benzo-cyclohepta-thiophene
US4072756A (en) * 1973-05-17 1978-02-07 Sandoz Ltd. Tricyclo piperidino ketones and soporific compositions thereof
CA1041100A (en) * 1973-10-04 1978-10-24 Herbert G. Johnson Pyridine-diyldioxamic acid and derivatives
CH580621A5 (enExample) * 1973-10-08 1976-10-15 Sandoz Ag
US4073915A (en) * 1975-05-20 1978-02-14 Sandoz Ltd. Treating asthma
FI761607A7 (enExample) * 1975-06-16 1976-12-17 Sandoz Ag
US4128549A (en) * 1976-02-27 1978-12-05 Sandoz Ltd. Precursors of 4-(1-alkyl-4-piperidylidene-4H-benzo[4,5]cyclohepta-[1,2-b]thiophen-10(9H)-ones
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
NL8701335A (nl) * 1986-06-21 1988-01-18 Sandoz Ag Orale farmaceutische preparaten.
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
US5438062A (en) * 1986-10-31 1995-08-01 Schering Corporation Benzo(5,6)cycloheptapyridines, compositions and methods of use
DZ1460A1 (fr) * 1989-11-22 2004-09-13 Sod Conseils Rech Applic Nouveaux dérivés du sélénophèn ainsi que leur procédé de préparation.
CA2038417A1 (en) * 1990-04-11 1991-10-12 Yasuo Ito Piperidine compounds, method for preparation thereof, and a pharmaceutical composition comprising the same
WO1992006981A1 (en) * 1990-10-10 1992-04-30 Schering Corporation Substituted imidazobenzazepines and imidazopyridoazepines
US5891460A (en) * 1995-06-07 1999-04-06 University Of Southern California University Park Campus Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof
WO1998056381A1 (en) * 1997-06-09 1998-12-17 Bridge Pharma, Inc. Compounds with combined antihistaminic and mast cell stabilizing activities, intended for ophthalmic use
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
MXPA02002658A (es) 1999-09-13 2002-10-23 Bridge Pharma Inc Isomeros opticamente activos de ketotifeno y metabolitos terapeuticamente activos de los mismos.
WO2001039774A1 (en) * 1999-12-01 2001-06-07 Klein Pharmaceuticals Topical administration of ketotifen
US20030212078A1 (en) * 2001-05-17 2003-11-13 Klein Gerald L. Topical administration of pharmacological compositions for non-systemic treatment of pruritus
KR20080032014A (ko) 2003-01-14 2008-04-11 길리애드 사이언시즈, 인코포레이티드 복합 항바이러스 치료를 위한 조성물 및 방법
CN100381439C (zh) * 2005-04-05 2008-04-16 浙江华海药业股份有限公司 9,10-二溴-9,10-二氢-4-H苯并[4,5]环庚烯并[1,2-b]噻吩-4-酮的制备方法
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) * 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
US20100166804A1 (en) * 2007-05-23 2010-07-01 Dennis Penn Methods
WO2009096080A1 (ja) 2008-01-30 2009-08-06 Nippon Zoki Pharmaceutical Co., Ltd. ピペリジン誘導体
WO2009142772A2 (en) 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
JP5379139B2 (ja) * 2008-08-01 2013-12-25 日本臓器製薬株式会社 アミノプロピリデン誘導体
US8536342B2 (en) * 2009-07-28 2013-09-17 Nippon Zoki Pharmaceutical Co., Ltd. Process for producing thiabenzoazulene-propionic acid derivative
JP6217938B2 (ja) 2011-10-28 2017-10-25 ルメナ ファーマシューティカルズ エルエルシー 小児の胆汁うっ滞性肝疾患の処置のための胆汁酸再循環阻害剤
CA2852957C (en) 2011-10-28 2020-08-04 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease
US8778971B2 (en) 2012-10-23 2014-07-15 Bridge Pharma, Inc. Medicinal treatment of dermal diseases in companion animals
US8557846B1 (en) 2012-10-23 2013-10-15 Bridge Pharma, Inc. Medicinal treatment of dermal diseases in dogs
US20140120121A1 (en) 2012-10-30 2014-05-01 Bridge Pharma, Inc. Medicinal treatment of atopic inflammatory diseases
US20150272941A1 (en) 2012-10-30 2015-10-01 Bridge Pharma, Inc. Medicinal treatment of chronic pulmonary inflammatory diseases with norketotifen
US9439895B2 (en) 2013-08-06 2016-09-13 Bridge Pharma, Inc. Methods of treating pruritic conditions mediated through non-histaminergic mechanisms in diabetic patients
US9345697B2 (en) 2013-08-06 2016-05-24 Bridge Pharma, Inc. Methods of treatment of non-histaminic pruritus
US9138431B2 (en) 2013-08-06 2015-09-22 Bridge Pharma, Inc. Methods of treatment of histamine H-4 receptor-related pruritus
WO2016200578A1 (en) 2015-06-11 2016-12-15 Bridge Pharma, Inc. Methods of treatment of non-histaminic pruritus in mammals
MX2018011699A (es) 2018-09-26 2019-07-24 Federico Amezcua Amezcua Composicion farmaceutica sinergica de un antagonista de los receptores de leucotrienos y un agonista inverso de la histamina h1.
US10959992B2 (en) 2019-02-22 2021-03-30 Bridge Pharma Inc. Methods of treatment of asthma and COPD

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130095C (enExample) * 1962-08-31
FR1437412A (fr) * 1963-12-19 1966-05-06 Sandoz Sa Nouveaux benzo-cyclohepta-thiophènes et leur préparation
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
GB1084450A (en) * 1963-12-20 1967-09-20 Sandoz Ltd Improvements in or relating to 4h-benzo[4,5]cyclohepta-[1,2-b] thiophene derivatives
CH537897A (de) * 1968-03-20 1973-06-15 Hoffmann La Roche Verfahren zur Herstellung von tricyclischen Verbindungen
US3574199A (en) * 1968-06-28 1971-04-06 Searle & Co 6-(aminoalkyl- and aminoalkylidene)-1,1a,6,10b -tetrahydro-dibenzo(a,e)cyclopropa(c)cycloheptenes
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene
US3709947A (en) * 1971-07-26 1973-01-09 Searle & Co 6-chloropropylidene-1,1a,6,10b-tetrahydrobenzo(a,e)cyclopropa(c)cycloheptenes

Also Published As

Publication number Publication date
GB1355538A (en) 1974-06-05
NL167431C (nl) 1981-12-16
OA03786A (fr) 1971-12-24
AT321905B (de) 1975-04-25
CA947767A (en) 1974-05-21
US3770728A (en) 1973-11-06
LU63829A1 (enExample) 1972-06-27
NL171449C (nl) 1983-04-05
SE378820B (enExample) 1975-09-15
US3853915A (en) 1974-12-10
DE2111071A1 (de) 1971-09-23
NL7103174A (enExample) 1971-09-14
BE771964A (fr) 1972-02-29
DE2111071C3 (de) 1979-07-12
US3682930A (en) 1972-08-08
BE764019A (fr) 1971-09-09
CA960673A (en) 1975-01-07
AT319238B (de) 1974-12-10
NL7111808A (enExample) 1972-03-28
CH531000A (de) 1972-11-30
FR2085695A1 (enExample) 1971-12-31
OA03692A (fr) 1971-12-24
FR2085695B1 (enExample) 1974-11-15
DE2144490A1 (de) 1972-03-30
LU62757A1 (enExample) 1971-10-13
SE368954B (enExample) 1974-07-29
DE2111071B2 (de) 1978-11-09
US3749786A (en) 1973-07-31
GB1355539A (en) 1974-06-05
GB1355537A (en) 1974-06-05
FR2107917B1 (enExample) 1975-04-18
GB1360219A (en) 1974-07-17

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Legal Events

Date Code Title Description
ST Notification of lapse