FR08C0046I1 - Reconstitution in vitro de virus a arn de polarite negative segmentes - Google Patents

Reconstitution in vitro de virus a arn de polarite negative segmentes

Info

Publication number
FR08C0046I1
FR08C0046I1 FR08C0046C FR08C0046I1 FR 08C0046 I1 FR08C0046 I1 FR 08C0046I1 FR 08C0046 C FR08C0046 C FR 08C0046C FR 08C0046 I1 FR08C0046 I1 FR 08C0046I1
Authority
FR
France
Prior art keywords
segmented
polarity
rna viruses
negative rna
vitro reconstruction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
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English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icahn School of Medicine at Mount Sinai
Original Assignee
Mount Sinai School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315773&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR08C0046(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9916794.2A external-priority patent/GB9916794D0/en
Application filed by Mount Sinai School of Medicine filed Critical Mount Sinai School of Medicine
Publication of FR08C0046I1 publication Critical patent/FR08C0046I1/fr
Application granted granted Critical
Publication of FR08C0046I2 publication Critical patent/FR08C0046I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FR08C0046C 1999-07-14 2008-11-13 Reconstitution in vitro de virus a arn de polarite negative segmentes Active FR08C0046I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14364599P 1999-07-14 1999-07-14
GBGB9916794.2A GB9916794D0 (en) 1999-07-16 1999-07-16 In vitro virus reconstitution
PCT/GB2000/002710 WO2001004333A1 (fr) 1999-07-14 2000-07-14 Reconstitution in vitro de virus a arn de polarite negative segmentes

Publications (2)

Publication Number Publication Date
FR08C0046I1 true FR08C0046I1 (fr) 2009-01-02
FR08C0046I2 FR08C0046I2 (fr) 2011-11-25

Family

ID=26315773

Family Applications (1)

Application Number Title Priority Date Filing Date
FR08C0046C Active FR08C0046I2 (fr) 1999-07-14 2008-11-13 Reconstitution in vitro de virus a arn de polarite negative segmentes

Country Status (12)

Country Link
EP (1) EP1194580B2 (fr)
AT (1) ATE353370T1 (fr)
AU (1) AU5998400A (fr)
CA (1) CA2379012C (fr)
CY (2) CY1106404T1 (fr)
DE (5) DE122008000057I1 (fr)
DK (1) DK1194580T4 (fr)
ES (1) ES2278621T5 (fr)
FR (1) FR08C0046I2 (fr)
LU (1) LU91367I2 (fr)
NL (4) NL300294I2 (fr)
WO (1) WO2001004333A1 (fr)

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FR2866031B1 (fr) * 2004-02-11 2012-10-19 David Francois Joseph Millet Chimere de virus pathogene emergent, medicament la contenant et utilisation en therapie antivirale
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US8137676B2 (en) 2005-02-15 2012-03-20 Mount Sinai School Of Medicine Genetically engineered equine influenza virus and uses thereof
US7959929B2 (en) 2005-04-21 2011-06-14 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
US11865172B2 (en) 2005-04-21 2024-01-09 University Of Florida Research Foundation, Inc. Materials and methods for respiratory disease control in canines
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EP1976559B3 (fr) 2006-01-27 2020-02-19 Seqirus UK Limited Vaccins contre la grippe contenant des hémaglutinines et des protéines matricielles
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JP5491173B2 (ja) * 2006-04-19 2014-05-14 メディミューン，エルエルシー イヌ細胞中でマイナス鎖ウイルスｒｎａを発現させるための方法および組成物
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CA3016948A1 (fr) 2006-09-11 2008-03-20 Seqirus UK Limited Fabrication de vaccins contre le virus grippal sans utiliser d'oeufs
EA200900784A1 (ru) 2006-12-06 2009-12-30 Новартис Аг Вакцины, включающие антиген из четырех штаммов вируса гриппа
US8597661B2 (en) 2007-05-04 2013-12-03 Wisconsin Alumni Research Foundation Neuraminidase-deficient live influenza vaccines
US8043856B2 (en) 2007-06-14 2011-10-25 Wisconsin Alumni Research Foundation Adenoviral vectors for influenza virus production
EP2045323A1 (fr) * 2007-10-05 2009-04-08 Avir Green Hills Biotechnology Research Development Trade Ag Constructions linéaires d'expression pour la production de particules de virus influenza
EP2185191B1 (fr) 2007-06-27 2012-09-12 Novartis AG Vaccins antigrippaux à faible teneur en additifs
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
EP2889042A3 (fr) 2008-03-18 2015-10-14 Novartis AG Améliorations dans la préparation d'antigènes de vaccin contre le virus de la grippe
EP2233568A1 (fr) 2009-03-19 2010-09-29 Avir Green Hills Biotechnology Research Development Trade AG Nouveau procédé pour la génération de virus d'ARN
WO2010091262A1 (fr) 2009-02-05 2010-08-12 Mount Sinai School Of Medicine Of New York University Virus chimériques de la maladie de newcastle et leurs utilisations
WO2010092476A1 (fr) 2009-02-10 2010-08-19 Novartis Ag Régimes de vaccin antigrippal pour souches liées à une pandémie
WO2010092477A1 (fr) 2009-02-10 2010-08-19 Novartis Ag Vaccins contre l'influenza possédant des quantités accrues d'antigène h3
ES2608841T3 (es) 2009-02-10 2017-04-17 Seqirus UK Limited Vacunas contra la gripe con cantidades reducidas de escualeno
WO2010117786A1 (fr) 2009-03-30 2010-10-14 Mount Sinai School Of Medicine Of New York University Vaccins pour le virus influenza et leurs utilisations
WO2010125461A1 (fr) 2009-04-27 2010-11-04 Novartis Ag Vaccins avec adjuvants pour protéger du virus de la grippe
US9217157B2 (en) 2009-07-27 2015-12-22 Icahn School Of Medicine At Mount Sinai Recombinant influenza viruses and uses thereof
WO2011014645A1 (fr) 2009-07-30 2011-02-03 Mount Sinai School Of Medicine Of New York University Virus de la grippe et leurs utilisations
CN102695523A (zh) 2009-09-10 2012-09-26 诺华有限公司 针对呼吸道疾病的组合疫苗
KR20130075732A (ko) 2010-03-30 2013-07-05 마운트 시나이 스쿨 오브 메디슨 인플루엔자 바이러스 백신 및 이의 용도
CA2801268A1 (fr) 2010-06-02 2011-12-08 Avir Green Hills Biotechnology Research Development Trade Ag Nouveau procede de generation d'un virus a arn
EP2747778B1 (fr) 2011-08-26 2017-12-06 Wisconsin Alumni Research Foundation Virus de la grippe ayant un segment génique pb2 mutant en tant que vaccins vivants atténués
AU2012312529B2 (en) 2011-09-20 2018-01-04 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
US20140248320A1 (en) 2011-10-20 2014-09-04 Novartis Ag Adjuvanted influenza b virus vaccines for pediatric priming
EP2708552A1 (fr) 2012-09-12 2014-03-19 Medizinische Universität Wien Virus de la grippe
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WO2014099931A1 (fr) 2012-12-18 2014-06-26 Icahn School Of Medicine At Mount Sinai Vaccins contre le virus de la grippe et leurs utilisations
US20140274806A1 (en) 2013-03-15 2014-09-18 Synthetic Genomics Vaccines Influenza virus reassortment
BR112015017420A2 (pt) * 2013-01-23 2017-07-11 Novartis Ag recombinação de vírus influenza
CN111218429A (zh) 2013-03-14 2020-06-02 西奈山伊坎医学院 新城疫病毒及其用途
WO2014159960A1 (fr) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Anticorps contre l'hémagglutinine du virus de la grippe et utilisations correspondantes
EP3110443A4 (fr) 2014-02-27 2017-11-15 Viralytics Limited Thérapie combinée pour le traitement du cancer
US10053671B2 (en) 2014-06-20 2018-08-21 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to additional genes in influenza viruses
CL2014003146A1 (es) * 2014-11-20 2015-06-12 Univ Santiago Chile Método para producir virus arn monocatenario negativo; plásmido recombinante funcional en células animales, que consta de un esqueleto pss-urg; método de obtención de partículas virales; y uso para expresar arn, proteínas autógenas o exógenas al virus.
CA2974699A1 (fr) 2015-01-23 2016-07-28 Icahn School Of Medicine At Mount Sinai Regimes de vaccination contre le virus de la grippe
AU2016222962B2 (en) 2015-02-26 2020-05-21 Boehringer Ingelheim Vetmedica Gmbh Bivalent swine influenza virus vaccine
KR20180035807A (ko) 2015-06-26 2018-04-06 세퀴러스 유케이 리미티드 항원적으로 매치된 인플루엔자 백신
KR20230132628A (ko) 2015-07-07 2023-09-15 세퀴러스 유케이 리미티드 인플루엔자 효능 검정
WO2017040203A1 (fr) 2015-08-28 2017-03-09 Yoshihiro Kawaoka Génération de virus de la grippe infectieux à partir de pseudo-particules virales (vlp)
BR112018075032A2 (pt) 2016-06-15 2019-03-26 Icahn School Of Medicine At Mount Sinai proteínas de hemaglutinina do vírus influenza e seus uso
EP3606555A4 (fr) 2017-04-07 2021-08-04 Icahn School of Medicine at Mount Sinai Anticorps anti-neuraminidase du virus influenza de type b et leurs utilisations
JOP20190256A1 (ar) 2017-05-12 2019-10-28 Icahn School Med Mount Sinai فيروسات داء نيوكاسل واستخداماتها
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Also Published As

Publication number Publication date
ES2278621T3 (es) 2007-08-16
NL300369I1 (nl) 2009-01-05
CY2007023I2 (el) 2009-11-04
DE122007000070I1 (de) 2008-01-31
DE60033284D1 (de) 2007-03-22
CY1106404T1 (el) 2010-07-28
DK1194580T3 (da) 2007-04-10
WO2001004333A1 (fr) 2001-01-18
NL300301I1 (nl) 2008-01-02
NL300368I1 (nl) 2009-01-05
ATE353370T1 (de) 2007-02-15
EP1194580A1 (fr) 2002-04-10
NL300301I2 (nl) 2008-10-01
DE122007000061I1 (de) 2007-12-20
DE122008000056I1 (de) 2009-04-09
DE60033284T2 (de) 2007-10-25
LU91367I2 (fr) 2007-11-21
NL300294I2 (nl) 2008-10-01
CA2379012A1 (fr) 2001-01-18
NL300294I1 (nl) 2007-12-03
ES2278621T5 (es) 2011-02-02
CY2007023I1 (el) 2009-11-04
CA2379012C (fr) 2013-07-02
FR08C0046I2 (fr) 2011-11-25
DE122008000057I1 (de) 2009-04-09
NL300368I2 (nl) 2017-08-03
DE122007000061I2 (de) 2011-07-21
EP1194580B2 (fr) 2010-08-25
DK1194580T4 (da) 2011-01-03
DE60033284T3 (de) 2014-10-30
EP1194580B1 (fr) 2007-02-07
AU5998400A (en) 2001-01-30

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