FI972238A - Terminaaliseen toistumasekvenssiin perustuva monistusmenetelmä - Google Patents

Terminaaliseen toistumasekvenssiin perustuva monistusmenetelmä Download PDF

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Publication number
FI972238A
FI972238A FI972238A FI972238A FI972238A FI 972238 A FI972238 A FI 972238A FI 972238 A FI972238 A FI 972238A FI 972238 A FI972238 A FI 972238A FI 972238 A FI972238 A FI 972238A
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FI
Finland
Prior art keywords
rna
dna
template
sequence
promoter
Prior art date
Application number
FI972238A
Other languages
English (en)
Swedish (sv)
Other versions
FI972238A0 (fi
Inventor
Roy Sooknanan
Lawrence Malek
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of FI972238A0 publication Critical patent/FI972238A0/fi
Publication of FI972238A publication Critical patent/FI972238A/fi

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Amplifiers (AREA)
  • Steroid Compounds (AREA)
  • Seal Device For Vehicle (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Electrotherapy Devices (AREA)
  • Channel Selection Circuits, Automatic Tuning Circuits (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
FI972238A 1994-11-28 1997-05-27 Terminaaliseen toistumasekvenssiin perustuva monistusmenetelmä FI972238A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/345,505 US5665545A (en) 1994-11-28 1994-11-28 Terminal repeat amplification method
PCT/EP1995/004694 WO1996017079A1 (en) 1994-11-28 1995-11-28 Terminal repeat amplification method

Publications (2)

Publication Number Publication Date
FI972238A0 FI972238A0 (fi) 1997-05-27
FI972238A true FI972238A (fi) 1997-05-27

Family

ID=23355318

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972238A FI972238A (fi) 1994-11-28 1997-05-27 Terminaaliseen toistumasekvenssiin perustuva monistusmenetelmä

Country Status (10)

Country Link
US (1) US5665545A (fi)
EP (1) EP0796343B1 (fi)
JP (1) JP3745774B2 (fi)
AT (1) ATE206467T1 (fi)
AU (1) AU711589B2 (fi)
CA (1) CA2205563A1 (fi)
DE (1) DE69523068T2 (fi)
ES (1) ES2168112T3 (fi)
FI (1) FI972238A (fi)
WO (1) WO1996017079A1 (fi)

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US6743605B1 (en) * 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
ATE374833T1 (de) 1998-11-09 2007-10-15 Eiken Chemical Verfahren zur synthese von nukleinsäuren
US6864050B2 (en) * 1999-07-30 2005-03-08 Affymetrix, Inc. Single-phase amplification of nucleic acids
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
NZ517121A (en) * 1999-09-13 2004-05-28 Nugen Technologies Inc Methods and compositions for linear isothermal amplification of polynucleotide sequences
US6686156B2 (en) * 2000-06-26 2004-02-03 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
US7846733B2 (en) 2000-06-26 2010-12-07 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
ATE475720T1 (de) 2000-12-13 2010-08-15 Nugen Technologies Inc Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben
US7094536B2 (en) * 2001-03-09 2006-08-22 Nugen Technologies, Inc. Methods and compositions for amplification of RNA sequences
AU2002252279B2 (en) 2001-03-09 2005-05-12 Nugen Technologies, Inc. Methods and compositions for amplification of RNA sequences
US7838270B2 (en) * 2001-05-22 2010-11-23 The University Of Chicago Target-dependent transcription using deletion mutants of N4 RNA polymerase
US8137911B2 (en) * 2001-05-22 2012-03-20 Cellscript, Inc. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
US7432084B2 (en) * 2001-08-31 2008-10-07 Rosetta Inpharmatics Llc Methods for preparing nucleic acid samples
CA2478875A1 (en) * 2002-03-11 2003-09-25 Nugen Technologies, Inc. Methods for generating double stranded dna comprising a 3' single stranded portion and uses of these complexes for recombination
SE0202867D0 (sv) * 2002-09-27 2002-09-27 Pyrosequencing Ab New sequencing method
CN102268428A (zh) * 2002-11-21 2011-12-07 震源技术公司 使用编码双链启动子一条链的引物的方法
EP1613778B1 (en) * 2003-04-14 2014-11-26 Nugen Technologies, Inc. Global amplification using a randomly primed composite primer
ATE494392T1 (de) * 2004-09-21 2011-01-15 Life Technologies Corp Zweifarbige echtzeit/endpunkt-quantifizierung von mikro-rnas (mirnas)
WO2006081222A2 (en) * 2005-01-25 2006-08-03 Compass Genetics, Llc. Isothermal dna amplification
US7939258B2 (en) 2005-09-07 2011-05-10 Nugen Technologies, Inc. Nucleic acid amplification procedure using RNA and DNA composite primers
US7501254B2 (en) 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
EP2173872B1 (en) 2007-06-29 2014-04-02 CellScript, Inc. Copy dna and sense rna
US8034568B2 (en) 2008-02-12 2011-10-11 Nugen Technologies, Inc. Isothermal nucleic acid amplification methods and compositions
WO2009117698A2 (en) 2008-03-21 2009-09-24 Nugen Technologies, Inc. Methods of rna amplification in the presence of dna
JP5481841B2 (ja) * 2008-11-28 2014-04-23 東ソー株式会社 サイトケラチン１９ｍＲＮＡの測定方法
EP3578205A1 (en) 2010-08-06 2019-12-11 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
CN104531812A (zh) 2010-10-01 2015-04-22 现代治疗公司 设计核酸及其使用方法
DK2665833T3 (en) 2011-01-17 2017-07-24 Life Technologies Corp WORKING PROCEDURE FOR DETECTING LIGANDS USING NUCLEIC ACIDS
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES2911677T3 (es) 2011-10-03 2022-05-20 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
RS63244B1 (sr) 2011-12-16 2022-06-30 Modernatx Inc Kompozicije modifikovane mrna
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US20140010861A1 (en) 2012-04-02 2014-01-09 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
CN102943100B (zh) * 2012-11-23 2014-04-16 郑州安图生物工程股份有限公司 高效RNA逆转录合成cDNA的方法
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
CN107208162B (zh) * 2015-02-26 2020-12-29 株式会社日立高新技术 核酸分子的构建方法
WO2021007233A1 (en) * 2019-07-10 2021-01-14 The Board Of Trustees Of The Leland Stanford Junior University Rna replication using transcription polymerases

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Also Published As

Publication number Publication date
JP3745774B2 (ja) 2006-02-15
CA2205563A1 (en) 1996-06-06
DE69523068T2 (de) 2002-06-06
ES2168112T3 (es) 2002-06-01
WO1996017079A1 (en) 1996-06-06
EP0796343A1 (en) 1997-09-24
FI972238A0 (fi) 1997-05-27
EP0796343B1 (en) 2001-10-04
AU711589B2 (en) 1999-10-14
JPH10510161A (ja) 1998-10-06
US5665545A (en) 1997-09-09
ATE206467T1 (de) 2001-10-15
DE69523068D1 (en) 2001-11-08
AU4176796A (en) 1996-06-19

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