ATE470710T1 - Auf nasba basiertes detektionsverfahren zur detektion des tuberkelbazillus - Google Patents
Auf nasba basiertes detektionsverfahren zur detektion des tuberkelbazillusInfo
- Publication number
- ATE470710T1 ATE470710T1 AT02749365T AT02749365T ATE470710T1 AT E470710 T1 ATE470710 T1 AT E470710T1 AT 02749365 T AT02749365 T AT 02749365T AT 02749365 T AT02749365 T AT 02749365T AT E470710 T1 ATE470710 T1 AT E470710T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- sequences
- genes
- complementary
- dna
- Prior art date
Links
- 241000193830 Bacillus <bacterium> Species 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title abstract 2
- 108020004414 DNA Proteins 0.000 abstract 5
- 102000053602 DNA Human genes 0.000 abstract 4
- 230000000295 complement effect Effects 0.000 abstract 4
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 2
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 abstract 2
- 108020004682 Single-Stranded DNA Proteins 0.000 abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 2
- 230000003321 amplification Effects 0.000 abstract 2
- 238000010804 cDNA synthesis Methods 0.000 abstract 2
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 2
- 238000013518 transcription Methods 0.000 abstract 2
- 230000035897 transcription Effects 0.000 abstract 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 102100034343 Integrase Human genes 0.000 abstract 1
- 101710203526 Integrase Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001224436A JP2003033182A (ja) | 2001-07-25 | 2001-07-25 | 結核菌検出のためのオリゴヌクレオチド |
| JP2001240874A JP2003047478A (ja) | 2001-08-08 | 2001-08-08 | 結核菌のｐａｂ遺伝子の検出法 |
| PCT/JP2002/007508 WO2003010309A1 (en) | 2001-07-25 | 2002-07-24 | Oligonucleotides for detecting tubercle bacillus and method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE470710T1 true ATE470710T1 (de) | 2010-06-15 |
Family
ID=26619238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02749365T ATE470710T1 (de) | 2001-07-25 | 2002-07-24 | Auf nasba basiertes detektionsverfahren zur detektion des tuberkelbazillus |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7105319B2 (de) |
| EP (1) | EP1411117B1 (de) |
| KR (1) | KR100984264B1 (de) |
| CN (1) | CN100351374C (de) |
| AT (1) | ATE470710T1 (de) |
| DE (1) | DE60236659D1 (de) |
| TW (1) | TWI243855B (de) |
| WO (1) | WO2003010309A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100984264B1 (ko) * | 2001-07-25 | 2010-09-30 | 토소가부시키가이샤 | 결핵균 검출을 위한 올리고뉴클레오티드 및 방법 |
| CN100999550B (zh) * | 2006-01-10 | 2010-10-06 | 中国人民解放军第三○九医院 | 结核分枝杆菌融合蛋白及其应用 |
| CN101298471B (zh) * | 2006-06-06 | 2011-01-19 | 中国人民解放军第二军医大学 | 激发人体抗结核杆菌的保护性免疫反应的抗原表位及其用途 |
| CN100415771C (zh) * | 2006-06-06 | 2008-09-03 | 中国人民解放军第二军医大学 | 激发人体抗结核杆菌的保护性免疫反应的抗原表位及其用途 |
| CN101857903B (zh) * | 2010-06-11 | 2013-02-06 | 亚能生物技术（深圳）有限公司 | 分枝杆菌菌种检测膜条及试剂盒 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631130A (en) * | 1994-05-13 | 1997-05-20 | Abbott Laboratories | Materials and methods for the detection of Mycobacterium tuberculosis |
| WO1998016645A2 (en) * | 1996-10-11 | 1998-04-23 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| EP1002878A3 (de) * | 1998-11-19 | 2003-11-12 | Tosoh Corporation | Hepatitis C Viren RNS-bindendes oligo DNS und Verfahren für dessen Herstellung |
| EP1055734B1 (de) * | 1999-05-24 | 2004-10-13 | Tosoh Corporation | Methode zum Nachweis von Ribonukleinsäuren |
| EP1103624A4 (de) * | 1999-06-04 | 2004-12-22 | Tosoh Corp | Verbessertes verfahren zur amplifikation von nukleinsäuren |
| KR100984264B1 (ko) * | 2001-07-25 | 2010-09-30 | 토소가부시키가이샤 | 결핵균 검출을 위한 올리고뉴클레오티드 및 방법 |
| JP2003116543A (ja) * | 2001-10-10 | 2003-04-22 | Tosoh Corp | 薬効と毒性の評価法 |
-
2002
- 2002-07-24 KR KR1020037004251A patent/KR100984264B1/ko not_active Expired - Fee Related
- 2002-07-24 DE DE60236659T patent/DE60236659D1/de not_active Expired - Lifetime
- 2002-07-24 AT AT02749365T patent/ATE470710T1/de not_active IP Right Cessation
- 2002-07-24 WO PCT/JP2002/007508 patent/WO2003010309A1/ja not_active Ceased
- 2002-07-24 CN CNB028025067A patent/CN100351374C/zh not_active Expired - Fee Related
- 2002-07-24 US US10/381,256 patent/US7105319B2/en not_active Expired - Fee Related
- 2002-07-24 TW TW091116495A patent/TWI243855B/zh not_active IP Right Cessation
- 2002-07-24 EP EP02749365A patent/EP1411117B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1411117A4 (de) | 2005-09-07 |
| CN100351374C (zh) | 2007-11-28 |
| US20040087782A1 (en) | 2004-05-06 |
| US7105319B2 (en) | 2006-09-12 |
| EP1411117A1 (de) | 2004-04-21 |
| DE60236659D1 (de) | 2010-07-22 |
| WO2003010309A1 (en) | 2003-02-06 |
| TWI243855B (en) | 2005-11-21 |
| EP1411117B1 (de) | 2010-06-09 |
| KR100984264B1 (ko) | 2010-09-30 |
| CN1464906A (zh) | 2003-12-31 |
| KR20040017796A (ko) | 2004-02-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |