ATE206467T1 - 'terminal repeat'- amplifikation - Google Patents
'terminal repeat'- amplifikationInfo
- Publication number
- ATE206467T1 ATE206467T1 AT95940256T AT95940256T ATE206467T1 AT E206467 T1 ATE206467 T1 AT E206467T1 AT 95940256 T AT95940256 T AT 95940256T AT 95940256 T AT95940256 T AT 95940256T AT E206467 T1 ATE206467 T1 AT E206467T1
- Authority
- AT
- Austria
- Prior art keywords
- rna
- dna
- template
- sequence
- promoter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/345,505 US5665545A (en) | 1994-11-28 | 1994-11-28 | Terminal repeat amplification method |
PCT/EP1995/004694 WO1996017079A1 (en) | 1994-11-28 | 1995-11-28 | Terminal repeat amplification method |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE206467T1 true ATE206467T1 (de) | 2001-10-15 |
Family
ID=23355318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95940256T ATE206467T1 (de) | 1994-11-28 | 1995-11-28 | 'terminal repeat'- amplifikation |
Country Status (10)
Country | Link |
---|---|
US (1) | US5665545A (de) |
EP (1) | EP0796343B1 (de) |
JP (1) | JP3745774B2 (de) |
AT (1) | ATE206467T1 (de) |
AU (1) | AU711589B2 (de) |
CA (1) | CA2205563A1 (de) |
DE (1) | DE69523068T2 (de) |
ES (1) | ES2168112T3 (de) |
FI (1) | FI972238A (de) |
WO (1) | WO1996017079A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9620209D0 (en) * | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
CA2222769C (en) * | 1997-01-17 | 2001-06-12 | F. Hoffmann-La Roche Ag | Primers for the detection of hiv-1 |
US5928869A (en) * | 1997-05-30 | 1999-07-27 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
US6743605B1 (en) * | 1998-06-24 | 2004-06-01 | Enzo Life Sciences, Inc. | Linear amplification of specific nucleic acid sequences |
DE69940623D1 (de) | 1998-11-09 | 2009-04-30 | Eiken Chemical | Prozess zur Synthetisierung von Nukleinsäure |
US6864050B2 (en) * | 1999-07-30 | 2005-03-08 | Affymetrix, Inc. | Single-phase amplification of nucleic acids |
US6692918B2 (en) | 1999-09-13 | 2004-02-17 | Nugen Technologies, Inc. | Methods and compositions for linear isothermal amplification of polynucleotide sequences |
EP1218542B1 (de) * | 1999-09-13 | 2004-03-24 | Nugen Technologies, Inc. | Methoden und zusammensetzungen zur linearen isothermalen amplifikation von polynukleotidsequenzen |
US7846733B2 (en) | 2000-06-26 | 2010-12-07 | Nugen Technologies, Inc. | Methods and compositions for transcription-based nucleic acid amplification |
ATE455186T1 (de) * | 2000-06-26 | 2010-01-15 | Nugen Technologies Inc | Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren |
DE60142709D1 (de) | 2000-12-13 | 2010-09-09 | Nugen Technologies Inc | Methoden und zusammensetzungen zur generierung einer vielzahl von kopien von nukleinsäuresequenzen und methoden zur detektion derselben |
US7094536B2 (en) * | 2001-03-09 | 2006-08-22 | Nugen Technologies, Inc. | Methods and compositions for amplification of RNA sequences |
AU2002252279B2 (en) | 2001-03-09 | 2005-05-12 | Nugen Technologies, Inc. | Methods and compositions for amplification of RNA sequences |
US8137911B2 (en) * | 2001-05-22 | 2012-03-20 | Cellscript, Inc. | Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences |
WO2004059289A2 (en) * | 2001-05-22 | 2004-07-15 | Epicentre Technologies | Target-dependent transcription using deletion mutants of n4 rna polymerase |
US7432084B2 (en) * | 2001-08-31 | 2008-10-07 | Rosetta Inpharmatics Llc | Methods for preparing nucleic acid samples |
JP2005519621A (ja) * | 2002-03-11 | 2005-07-07 | ニューゲン テクノロジーズ, インコーポレイテッド | 3’一本鎖部分を含む二本鎖dnaを生成する方法および組換えのためのこれらの複合体の使用 |
SE0202867D0 (sv) * | 2002-09-27 | 2002-09-27 | Pyrosequencing Ab | New sequencing method |
AU2003297557B2 (en) | 2002-11-21 | 2009-02-26 | Cellscript, Inc. | Methods for using primers that encode one strand of a double-stranded promoter |
CA2521084A1 (en) | 2003-04-14 | 2004-10-28 | Nugen Technologies, Inc. | Global amplification using a randomly primed composite primer |
WO2006034387A1 (en) * | 2004-09-21 | 2006-03-30 | Applera Corporation | TWO-COLOR REAL-TIME/END-POINT QUANTITATION OF MICRORNAS (miRNAs) |
WO2006081222A2 (en) * | 2005-01-25 | 2006-08-03 | Compass Genetics, Llc. | Isothermal dna amplification |
WO2007030759A2 (en) | 2005-09-07 | 2007-03-15 | Nugen Technologies, Inc. | Improved nucleic acid amplification procedure |
US7501254B2 (en) | 2006-07-20 | 2009-03-10 | Ghc Technologies, Inc. | Methods and compositions for amplification and capture of nucleic acid sequences |
EP2173872B1 (de) | 2007-06-29 | 2014-04-02 | CellScript, Inc. | Copy-dna und sense-rna |
US8034568B2 (en) | 2008-02-12 | 2011-10-11 | Nugen Technologies, Inc. | Isothermal nucleic acid amplification methods and compositions |
WO2009117698A2 (en) | 2008-03-21 | 2009-09-24 | Nugen Technologies, Inc. | Methods of rna amplification in the presence of dna |
JP5481841B2 (ja) * | 2008-11-28 | 2014-04-23 | 東ソー株式会社 | サイトケラチン19mRNAの測定方法 |
EP3578205A1 (de) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | Pharmazeutische zusammensetzungen enthaltenbearbeitete nukleinsäuren und ihre medizinische verwendung |
RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
EP2665833B1 (de) | 2011-01-17 | 2017-04-19 | Life Technologies Corporation | Arbeitsablauf zur nachweis von liganden mit nukleinsäuren |
JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
US9428535B2 (en) | 2011-10-03 | 2016-08-30 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof |
LT2791160T (lt) | 2011-12-16 | 2022-06-10 | Modernatx, Inc. | Modifikuotos mrnr sudėtys |
US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9192651B2 (en) | 2012-04-02 | 2015-11-24 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of secreted proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
CN102943100B (zh) * | 2012-11-23 | 2014-04-16 | 郑州安图生物工程股份有限公司 | 高效RNA逆转录合成cDNA的方法 |
WO2014081507A1 (en) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Terminally modified rna |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
CA2926218A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
DE112016000293T5 (de) * | 2015-02-26 | 2017-09-21 | Hitachi High-Technologies Corporation | Verfahren zum konstruieren eines nucleinsäure-moleküls |
US20220259645A1 (en) * | 2019-07-10 | 2022-08-18 | The Board Of Trustees Of The Leland Stanford Junior University | RNA Replication Using Transcription Polymerases |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
CA1340807C (en) * | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
US5130238A (en) * | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
JP2939485B2 (ja) * | 1988-09-08 | 1999-08-25 | ザ・ソーク・インスチュート・フォーバイオロジカル・スタディーズ | 複製rnaに基づく増幅/検出系 |
CA2020958C (en) * | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
US5215899A (en) * | 1989-11-09 | 1993-06-01 | Miles Inc. | Nucleic acid amplification employing ligatable hairpin probe and transcription |
NO904633L (no) * | 1989-11-09 | 1991-05-10 | Molecular Diagnostics Inc | Amplifikasjon av nukleinsyrer ved transkriberbar haarnaalsprobe. |
US5194370A (en) * | 1990-05-16 | 1993-03-16 | Life Technologies, Inc. | Promoter ligation activated transcription amplification of nucleic acid sequences |
NO174693C (no) * | 1990-05-22 | 1994-06-22 | Jacobsen Clas T | Fremgangsmåte ved anbringelse av brannbeskyttende belegg, såsom matter, på konstruksjoner |
WO1992018521A1 (en) * | 1991-04-10 | 1992-10-29 | Life Technologies, Inc. | Method for amplifying and altering an rna sequence |
US5169766A (en) * | 1991-06-14 | 1992-12-08 | Life Technologies, Inc. | Amplification of nucleic acid molecules |
AU672689B2 (en) * | 1991-08-30 | 1996-10-10 | University Of Medicine And Dentistry Of New Jersey | Over expression of single-stranded molecules |
DE4132133A1 (de) * | 1991-09-26 | 1993-04-01 | Boehringer Mannheim Gmbh | Verfahren zur spezifischen herstellung von ribonukleinsaeuren |
DE4213029A1 (de) * | 1991-09-26 | 1993-04-01 | Boehringer Mannheim Gmbh | Verfahren zur spezifischen vervielfaeltigung von nukleins aeuresequenzen |
US5411875A (en) * | 1991-11-01 | 1995-05-02 | University Of Iowa Research Foundation | Method for retrieval of unknown flanking DNA sequence |
US5278051A (en) * | 1991-12-12 | 1994-01-11 | New York University | Construction of geometrical objects from polynucleotides |
AU3729393A (en) * | 1992-02-20 | 1993-09-13 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University, The | Boomerand DNA amplification |
WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
CA2101119A1 (en) * | 1992-08-17 | 1994-02-18 | George T. Walker | Exonuclease decontamination method |
IL105894A (en) * | 1993-06-03 | 1997-02-18 | Asher Nathan | Method for the detection of nucleic acid sequence by using a detection ensemble and an amplification ensemble |
-
1994
- 1994-11-28 US US08/345,505 patent/US5665545A/en not_active Expired - Fee Related
-
1995
- 1995-11-28 ES ES95940256T patent/ES2168112T3/es not_active Expired - Lifetime
- 1995-11-28 EP EP95940256A patent/EP0796343B1/de not_active Expired - Lifetime
- 1995-11-28 WO PCT/EP1995/004694 patent/WO1996017079A1/en active IP Right Grant
- 1995-11-28 AU AU41767/96A patent/AU711589B2/en not_active Ceased
- 1995-11-28 JP JP51818496A patent/JP3745774B2/ja not_active Expired - Fee Related
- 1995-11-28 AT AT95940256T patent/ATE206467T1/de not_active IP Right Cessation
- 1995-11-28 DE DE69523068T patent/DE69523068T2/de not_active Expired - Fee Related
- 1995-11-28 CA CA002205563A patent/CA2205563A1/en not_active Abandoned
-
1997
- 1997-05-27 FI FI972238A patent/FI972238A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
JPH10510161A (ja) | 1998-10-06 |
DE69523068D1 (en) | 2001-11-08 |
JP3745774B2 (ja) | 2006-02-15 |
EP0796343A1 (de) | 1997-09-24 |
DE69523068T2 (de) | 2002-06-06 |
FI972238A0 (fi) | 1997-05-27 |
AU711589B2 (en) | 1999-10-14 |
AU4176796A (en) | 1996-06-19 |
US5665545A (en) | 1997-09-09 |
FI972238A (fi) | 1997-05-27 |
EP0796343B1 (de) | 2001-10-04 |
ES2168112T3 (es) | 2002-06-01 |
CA2205563A1 (en) | 1996-06-06 |
WO1996017079A1 (en) | 1996-06-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |