FI971934A - Acylerade bensylglykosider som inhibitorer för proliferationen hos släta muskler - Google Patents

Acylerade bensylglykosider som inhibitorer för proliferationen hos släta muskler Download PDF

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Publication number
FI971934A
FI971934A FI971934A FI971934A FI971934A FI 971934 A FI971934 A FI 971934A FI 971934 A FI971934 A FI 971934A FI 971934 A FI971934 A FI 971934A FI 971934 A FI971934 A FI 971934A
Authority
FI
Finland
Prior art keywords
carbon atoms
acyl group
phenylsulfonyl
cell proliferation
smooth muscle
Prior art date
Application number
FI971934A
Other languages
English (en)
Finnish (fi)
Other versions
FI971934A0 (sv
Inventor
Thomas T Nguyen
John Watson Ellingboe
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/531,142 external-priority patent/US5773420A/en
Application filed by American Home Prod filed Critical American Home Prod
Publication of FI971934A0 publication Critical patent/FI971934A0/sv
Publication of FI971934A publication Critical patent/FI971934A/sv

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
FI971934A 1994-11-07 1997-05-06 Acylerade bensylglykosider som inhibitorer för proliferationen hos släta muskler FI971934A (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33528694A 1994-11-07 1994-11-07
US08/531,142 US5773420A (en) 1994-11-07 1995-10-20 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation
PCT/US1995/014795 WO1996014325A1 (en) 1994-11-07 1995-11-03 Acylated benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (2)

Publication Number Publication Date
FI971934A0 FI971934A0 (sv) 1997-05-06
FI971934A true FI971934A (sv) 1997-05-06

Family

ID=26989635

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971934A FI971934A (sv) 1994-11-07 1997-05-06 Acylerade bensylglykosider som inhibitorer för proliferationen hos släta muskler

Country Status (16)

Country Link
EP (1) EP0791004B1 (sv)
JP (1) JPH10508610A (sv)
AT (1) ATE184283T1 (sv)
AU (1) AU703338B2 (sv)
BR (1) BR9509586A (sv)
CA (1) CA2204530A1 (sv)
DE (1) DE69512081T2 (sv)
DK (1) DK0791004T3 (sv)
ES (1) ES2136314T3 (sv)
FI (1) FI971934A (sv)
GR (1) GR3031731T3 (sv)
HU (1) HUT77757A (sv)
IL (1) IL115745A (sv)
MX (1) MX9702966A (sv)
NZ (1) NZ296037A (sv)
WO (1) WO1996014325A1 (sv)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1348460A (zh) * 1998-11-24 2002-05-08 美国家用产品公司 作为平滑肌细胞增殖抑制剂的缩醛苄基麦芽糖苷类
AU1633000A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
CN1333784A (zh) * 1998-11-24 2002-01-30 美国家用产品公司 用作平滑肌细胞增殖抑制剂的苄基麦芽糖苷
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
AU5706699A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
AU1919800A (en) * 1998-11-24 2000-06-13 American Home Products Corporation Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
EP1133510A2 (en) * 1998-11-24 2001-09-19 American Home Products Corporation Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US8106071B2 (en) 2007-02-21 2012-01-31 Biobud Co., Ltd. Compositions for treating hyperproliferative vascular disorders and cancers
CN110152001B (zh) * 2019-05-20 2021-08-10 昆山德瑞生物科技有限公司 小分子化合物的用途及其组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
DK0454220T3 (da) * 1990-04-23 1993-11-22 Sanofi Elf Carbohydratderivater omfattende en trisaccharidenhed

Also Published As

Publication number Publication date
WO1996014325A1 (en) 1996-05-17
NZ296037A (en) 1999-05-28
FI971934A0 (sv) 1997-05-06
JPH10508610A (ja) 1998-08-25
EP0791004A1 (en) 1997-08-27
AU703338B2 (en) 1999-03-25
EP0791004B1 (en) 1999-09-08
GR3031731T3 (en) 2000-02-29
MX9702966A (es) 1997-06-28
IL115745A (en) 2000-11-21
IL115745A0 (en) 1996-01-19
CA2204530A1 (en) 1996-05-17
DE69512081T2 (de) 2000-02-03
BR9509586A (pt) 1997-12-23
ES2136314T3 (es) 1999-11-16
DK0791004T3 (da) 1999-11-29
HUT77757A (hu) 1998-07-28
DE69512081D1 (de) 1999-10-14
ATE184283T1 (de) 1999-09-15
AU3935395A (en) 1996-05-31

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