FI962948A0 - Förfarande för att lösa svårlösliga farmaceutiskt aktiva ämnen - Google Patents

Förfarande för att lösa svårlösliga farmaceutiskt aktiva ämnen

Info

Publication number
FI962948A0
FI962948A0 FI962948A FI962948A FI962948A0 FI 962948 A0 FI962948 A0 FI 962948A0 FI 962948 A FI962948 A FI 962948A FI 962948 A FI962948 A FI 962948A FI 962948 A0 FI962948 A0 FI 962948A0
Authority
FI
Finland
Prior art keywords
active substances
pharmaceutically active
soluble pharmaceutically
difficult soluble
dissolving
Prior art date
Application number
FI962948A
Other languages
English (en)
Finnish (fi)
Other versions
FI962948A (sv
Inventor
Dadi Jamshed Dhabhar
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI962948A publication Critical patent/FI962948A/sv
Publication of FI962948A0 publication Critical patent/FI962948A0/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI962948A 1994-01-24 1996-07-23 Förfarande för att lösa svårlösliga farmaceutiskt aktiva ämnen FI962948A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18557694A 1994-01-24 1994-01-24
PCT/US1995/001018 WO1995019759A1 (en) 1994-01-24 1995-01-24 Process for solubilizing difficultly soluble pharmaceutical actives

Publications (2)

Publication Number Publication Date
FI962948A FI962948A (sv) 1996-07-23
FI962948A0 true FI962948A0 (sv) 1996-07-23

Family

ID=22681571

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962948A FI962948A0 (sv) 1994-01-24 1996-07-23 Förfarande för att lösa svårlösliga farmaceutiskt aktiva ämnen

Country Status (14)

Country Link
EP (1) EP0741560A1 (sv)
JP (1) JPH09508128A (sv)
CN (1) CN1138827A (sv)
AU (1) AU706890B2 (sv)
BR (1) BR9506564A (sv)
CA (1) CA2181241C (sv)
CZ (1) CZ210496A3 (sv)
FI (1) FI962948A0 (sv)
MX (1) MX9602955A (sv)
NO (1) NO963052L (sv)
NZ (1) NZ279443A (sv)
PL (1) PL315635A1 (sv)
SK (1) SK96196A3 (sv)
WO (1) WO1995019759A1 (sv)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058637A1 (en) * 1996-06-20 1998-12-30 Mcneil-Ppc Acetaminophen and diphenhydramine analgesics
ZA975444B (en) * 1996-06-20 1998-12-21 Mcneil Ppc Inc Acetaminophen and meclizine hydrochloride analgesics
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
US5763449A (en) * 1996-08-07 1998-06-09 Ascent Pediatrics, Inc. Pleasant-tasting aqueous liquid composition of a bitter-tasting drug
DE69940769D1 (de) * 1998-01-20 2009-06-04 Applied Analytical Ind Inc Orale flüssige zusammensetzungen
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
US20020086878A1 (en) * 1999-01-11 2002-07-04 Douglas Joseph Dobrozsi Compositions having improved stability
US20020082307A1 (en) * 1999-01-11 2002-06-27 Dobrozsi Douglas Joseph Compositions having improved stability
US6846495B2 (en) 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
FR2796843B1 (fr) * 1999-07-29 2003-05-09 So Ge Val Sa Composition antipyretique concentree et stabilisee a usage veterinaire destine a etre incorporee a l'alimentation des animaux ainsi que procede d'incorporation de cette composition a l'eau de boisson d'animaux
US6251426B1 (en) * 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
DE10011032A1 (de) * 2000-03-07 2001-09-13 Bayer Ag Acetylsalicylsäure-Lösungen
KR20020069387A (ko) * 2001-02-26 2002-09-04 진양제약주식회사 호박산독실아민 조성물 및 이 조성물을 함유한 연질캅셀제제
JP2004538309A (ja) * 2001-07-31 2004-12-24 ワイエス 不快な味覚をマスキングするためのスクラロース調合物
US7101572B2 (en) * 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
CN100379406C (zh) * 2003-09-22 2008-04-09 北京德众万全药物技术开发有限公司 一种难溶性药物微丸的制备方法及包含该微丸的制剂
CA2627292C (en) * 2005-10-26 2012-04-17 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
DE102005053066A1 (de) 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
EP1962908A2 (de) * 2005-12-09 2008-09-03 Basf Se Verwendung von polyvinyllactam-polyoxyalkylen-blockcopolymeren als solubilisatoren für in wasser schwerlösliche verbindungen
US8637076B2 (en) 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
JP2008184430A (ja) * 2007-01-30 2008-08-14 Ss Pharmaceut Co Ltd ソフトカプセル
CA2690488C (en) * 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
EP3158991B1 (en) 2010-01-28 2021-03-17 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
WO2013142359A1 (en) 2012-03-20 2013-09-26 Eagle Pharmaceuticals, Inc. Method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration
DK2827862T3 (da) 2012-03-20 2024-02-12 Eagle Pharmaceuticals Inc Formuleringer af bendamustin
KR101695580B1 (ko) * 2013-02-28 2017-01-13 화이자 인코포레이티드 증가된 안정성의 신규한 액체 조성물
GB201506755D0 (en) * 2015-04-21 2015-06-03 Reckitt Benckiser Llc Novel pharmaceutical formulation
TWI586379B (zh) 2015-06-29 2017-06-11 永信藥品工業股份有限公司 一種製作難溶藥物固體劑型的方法
WO2017062997A1 (en) 2015-10-09 2017-04-13 Reckitt Benckiser Llc Pharmaceutical formulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives

Also Published As

Publication number Publication date
SK96196A3 (en) 1997-03-05
NO963052L (no) 1996-09-24
EP0741560A1 (en) 1996-11-13
WO1995019759A1 (en) 1995-07-27
NZ279443A (en) 1998-04-27
BR9506564A (pt) 1997-09-02
FI962948A (sv) 1996-07-23
CA2181241A1 (en) 1995-07-27
MX9602955A (es) 1997-06-28
CZ210496A3 (en) 1996-12-11
CN1138827A (zh) 1996-12-25
PL315635A1 (en) 1996-11-25
AU706890B2 (en) 1999-07-01
JPH09508128A (ja) 1997-08-19
NO963052D0 (no) 1996-07-22
AU1607595A (en) 1995-08-08
CA2181241C (en) 2000-04-25

Similar Documents

Publication Publication Date Title
FI962948A0 (sv) Förfarande för att lösa svårlösliga farmaceutiskt aktiva ämnen
FI946173A0 (sv) Metoder för att förbättra läkemedelsupptagning med hjälp av modifierade saponiner
DE69531788D1 (de) Verbessertes bioadhäsives pharmazeutisches abgabesystem
ATE127799T1 (de) Therapeutisch aktive verbindung und verfahren zu deren herstellung.
DE69514087D1 (de) Pharmazeutisch aktive substituierte aromatische verbindungen
FI963298A0 (sv) Hydroxamsyra- och karboxylsyraderivat, förfarande för framställning av dessa och användning av dessa
PT759306E (pt) Aparelho de administracao de medicamentos
MA24800A1 (fr) Agent de blanchiment et son procede de preparation
GR3018318T3 (en) Pharmaceutical agents.
FI971279A (sv) Läkemedel
KR950703383A (ko) 초음파 경피약제전달 시스템(ultrasonic transdermal drug delivery system)
FI961437A (sv) System som avger aktivt ämne
DK1199307T3 (da) Farmaceutisk aktive benzoquinazolinforbindelser
AU4904700A (en) Process for drying medicinal plants
HU9801025D0 (en) Process for producing pharmaceutical active agent
FI943201A (sv) Anordning för avgivande av verksamt ämne
EE9400296A (et) Piperidinüültioindooli derivaadid, ravimvormid, aktiivne valuvaigisti, nende valmistamise meetodid
FI952890A0 (sv) Förfarande för framställning av vattenhaltig kopolymerlösning
HUP9802146A3 (en) Process for preparing optically active 2-amino-omega-oxoalkanoic acid derivatives and the compounds
DE60003662D1 (de) Pyridothienodiazepine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
NO940844D0 (no) Farmasöytisk aktive hydroksykarboksylsyrederivater
EE200000401A (et) Farmatseutilise preparaadi valmistamismeetod
AU9021591A (en) Tetracyclic amines having pharmaceutical activity
ZA988782B (en) Aporphinoid derivatives, processes for their production and pharmaceutical agents containing these compounds.
IL136230A0 (en) An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes