FI962494A0 - 5-(2-imidatsolinyyliamino)bentsimidatsolijohdannaisia, niiden valmistus ja niiden käyttö alpha-2-adrenoseptoriagonisteina - Google Patents

5-(2-imidatsolinyyliamino)bentsimidatsolijohdannaisia, niiden valmistus ja niiden käyttö alpha-2-adrenoseptoriagonisteina

Info

Publication number
FI962494A0
FI962494A0 FI962494A FI962494A FI962494A0 FI 962494 A0 FI962494 A0 FI 962494A0 FI 962494 A FI962494 A FI 962494A FI 962494 A FI962494 A FI 962494A FI 962494 A0 FI962494 A0 FI 962494A0
Authority
FI
Finland
Prior art keywords
imidazolinylamino
alpha
preparation
unsubstituted
benzimidazole derivatives
Prior art date
Application number
FI962494A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI962494A (fi
Inventor
Thomas Lee Cupps
Sophie Eva Bogdan
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26865464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI962494(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI962494A0 publication Critical patent/FI962494A0/fi
Publication of FI962494A publication Critical patent/FI962494A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI962494A 1993-12-17 1996-06-14 5-(2-imidatsolinyyliamino)bentsimidatsolijohdannaisia, niiden valmistus ja niiden käyttö alpha-2-adrenoseptoriagonisteina FI962494A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16986893A 1993-12-17 1993-12-17
US08/349,558 US5478858A (en) 1993-12-17 1994-12-08 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
PCT/US1994/014292 WO1995016685A1 (en) 1993-12-17 1994-12-15 5-(2-imidazolinylamino)benzimidazole derivatives, their preparation and their use as alpha-2 adrenoceptor agonists

Publications (2)

Publication Number Publication Date
FI962494A0 true FI962494A0 (fi) 1996-06-14
FI962494A FI962494A (fi) 1996-06-14

Family

ID=26865464

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962494A FI962494A (fi) 1993-12-17 1996-06-14 5-(2-imidatsolinyyliamino)bentsimidatsolijohdannaisia, niiden valmistus ja niiden käyttö alpha-2-adrenoseptoriagonisteina

Country Status (23)

Country Link
US (3) US5478858A (zh)
EP (1) EP0736022B1 (zh)
JP (1) JPH09507216A (zh)
KR (1) KR100385195B1 (zh)
CN (1) CN1076352C (zh)
AT (1) ATE250598T1 (zh)
AU (1) AU699631B2 (zh)
BR (1) BR9408343A (zh)
CA (1) CA2179008C (zh)
CZ (1) CZ286816B6 (zh)
DE (1) DE69433181T2 (zh)
ES (1) ES2202352T3 (zh)
FI (1) FI962494A (zh)
HU (1) HU224016B1 (zh)
MY (1) MY131696A (zh)
NO (1) NO309325B1 (zh)
NZ (1) NZ333371A (zh)
PL (1) PL180903B1 (zh)
RU (1) RU2143430C1 (zh)
SG (1) SG49049A1 (zh)
SK (1) SK282566B6 (zh)
TW (1) TW393469B (zh)
WO (1) WO1995016685A1 (zh)

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CA2196792A1 (en) 1994-08-04 1996-02-15 Yoon T. Jeon Novel benzimidazole derivatives
CN1090935C (zh) * 1995-02-28 2002-09-18 阿温蒂斯药物公司 哌啶子基烷醇化合物的药物组合物
US5677321A (en) 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
CA2272098C (en) * 1996-11-25 2003-11-11 The Procter & Gamble Company Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
KR20000069131A (ko) 1996-11-25 2000-11-25 데이비드 엠 모이어 알파-2 아드레날린수용체 아고니스트로서 유용한 구아니디닐 헤테로사이클 화합물
KR20000069104A (ko) * 1996-11-25 2000-11-25 데이비드 엠 모이어 알파-2 아드레날린수용체 아고니스트로서 유용한 2-이미다졸리닐아미노인다졸 화합물
US6306877B1 (en) 1999-08-09 2001-10-23 The Procter & Gamble Co. Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
US6172095B1 (en) 1996-11-25 2001-01-09 The Procter & Gamble Company Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
DE69730516T2 (de) * 1996-11-25 2005-09-01 The Procter & Gamble Company, Cincinnati 2-imidazolinylaminoindol verbindungen als alpha-2 adrenoceptor agonisten
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US7919119B2 (en) * 1999-05-27 2011-04-05 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US8889112B2 (en) * 1999-09-16 2014-11-18 Ocularis Pharma, Llc Ophthalmic formulations including selective alpha 1 antagonists
US7678387B2 (en) * 2000-06-06 2010-03-16 Capricorn Pharma, Inc. Drug delivery systems
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US20060189526A1 (en) * 2002-04-24 2006-08-24 Podolsky Daniel K Compositions containing an intestinal trefoil peptide and a mucoadhesive
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US20030105016A1 (en) * 2001-09-06 2003-06-05 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
US20040171544A1 (en) * 2001-04-24 2004-09-02 Barker Nicholas P. Trefoil domain-containing polypeptides and uses thereof
US20030181384A1 (en) * 2001-09-06 2003-09-25 Podolsky Daniel K. Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions
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US20030185839A1 (en) * 2001-10-05 2003-10-02 Podolsky Daniel K. Methods and compositions for treating dermal lesions
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US7777051B2 (en) * 2003-05-13 2010-08-17 Icagen, Inc. Asymmetric benzimidazoles and related compounds as potassium channel modulators
US8075771B2 (en) * 2005-02-17 2011-12-13 E. I. Du Pont De Nemours And Company Apparatus for magnetic field gradient enhanced centrifugation
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EP1896022B1 (en) * 2005-06-17 2012-10-31 AFT Pharmaceuticals Limited Novel pharmaceutical composition and its use in a method for treatment of patients with upper respiratory mucosal congestion
TWI435729B (zh) 2005-11-09 2014-05-01 Combinatorx Inc 治療病症之方法，組合物及套組
EP2525793B1 (en) 2010-01-21 2018-09-05 Allergan, Inc. Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
US20130210876A1 (en) * 2010-01-21 2013-08-15 Allergan, Inc Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
JP6052685B2 (ja) 2011-07-25 2016-12-27 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ α２アドレナリン受容体の調節因子としてのＮ−（イミダゾリジン−２−イリデン）−ヘテロシクロペンタ［ｂ］ピリジン誘導体
US9629847B2 (en) 2011-11-23 2017-04-25 Michael Leighton Compositions and methods for treating symptoms of inflammatory related conditions using a combination of an antihistamine and a stimulant
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AU2021222048A1 (en) 2020-02-20 2022-10-13 Allergan, Inc. Alpha-2-adrenergic receptor agonists for reducing redness and increasing whiteness in eyes and other ophthalmic purposes
CN115443125A (zh) * 2020-02-20 2022-12-06 阿勒根公司 α-2-肾上腺素能受体激动剂的药物组合物和其用于改善视力的用途

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Also Published As

Publication number Publication date
TW393469B (en) 2000-06-11
RU2143430C1 (ru) 1999-12-27
SG49049A1 (en) 1998-05-18
CN1137794A (zh) 1996-12-11
HU9601663D0 (en) 1996-08-28
AU1306295A (en) 1995-07-03
CN1076352C (zh) 2001-12-19
ATE250598T1 (de) 2003-10-15
NO309325B1 (no) 2001-01-15
NO962539D0 (no) 1996-06-14
US5691370A (en) 1997-11-25
DE69433181T2 (de) 2004-07-01
NO962539L (no) 1996-08-13
BR9408343A (pt) 1997-08-19
MY131696A (en) 2007-08-30
FI962494A (fi) 1996-06-14
PL180903B1 (pl) 2001-04-30
US5541210A (en) 1996-07-30
WO1995016685A1 (en) 1995-06-22
CZ175196A3 (en) 1996-11-13
CA2179008C (en) 1999-08-17
US5478858A (en) 1995-12-26
NZ333371A (en) 2001-12-21
CA2179008A1 (en) 1995-06-22
HU224016B1 (hu) 2005-04-28
DE69433181D1 (de) 2003-10-30
EP0736022B1 (en) 2003-09-24
CZ286816B6 (en) 2000-07-12
JPH09507216A (ja) 1997-07-22
EP0736022A1 (en) 1996-10-09
SK282566B6 (sk) 2002-10-08
HUT76473A (en) 1997-09-29
KR100385195B1 (ko) 2003-08-21
ES2202352T3 (es) 2004-04-01
PL315059A1 (en) 1996-09-30
SK77196A3 (en) 1997-03-05
AU699631B2 (en) 1998-12-10

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