ES2101646A1 - Nuevo compuesto derivado del cromeno. - Google Patents

Nuevo compuesto derivado del cromeno.

Info

Publication number
ES2101646A1
ES2101646A1 ES09500737A ES9500737A ES2101646A1 ES 2101646 A1 ES2101646 A1 ES 2101646A1 ES 09500737 A ES09500737 A ES 09500737A ES 9500737 A ES9500737 A ES 9500737A ES 2101646 A1 ES2101646 A1 ES 2101646A1
Authority
ES
Spain
Prior art keywords
chromene
new compound
compound derived
psychosis
schizophrenia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09500737A
Other languages
English (en)
Other versions
ES2101646B1 (es
Inventor
Rafael Fouget
Lluis Anglada
Jordi Bolos
Jose A Ortiz
Aurelio Sacristan
Josep M Castello
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES9500737A priority Critical patent/ES2101646B1/es
Priority to ES9600323A priority patent/ES2103237B1/es
Priority to TW085103637A priority patent/TW353071B/zh
Priority to IL11764696A priority patent/IL117646A/xx
Priority to ZA962391A priority patent/ZA962391B/xx
Priority to MX9601163A priority patent/MX9601163A/es
Priority to KR1019960707131A priority patent/KR100396474B1/ko
Priority to CA002192596A priority patent/CA2192596C/en
Priority to NZ306447A priority patent/NZ306447A/en
Priority to JP53071696A priority patent/JP3916662B2/ja
Priority to DK96912012T priority patent/DK0765323T3/da
Priority to EP96912012A priority patent/EP0765323B1/en
Priority to AU55004/96A priority patent/AU696494B2/en
Priority to PCT/EP1996/001551 priority patent/WO1996032389A1/en
Priority to DE69613783T priority patent/DE69613783T2/de
Priority to US08/750,790 priority patent/US5736558A/en
Priority to PT96912012T priority patent/PT765323E/pt
Priority to AT96912012T priority patent/ATE203022T1/de
Priority to NO965300A priority patent/NO307517B1/no
Publication of ES2101646A1 publication Critical patent/ES2101646A1/es
Application granted granted Critical
Publication of ES2101646B1 publication Critical patent/ES2101646B1/es
Priority to GR20010401686T priority patent/GR3036825T3/el
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NUEVO COMPUESTO DERIVADO DEL CROMENO. NUEVO COMPUESTO DERIVADO DEL CROMENO DE FORMULA (I), ASI COMO SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES, UTILES EN EL TRATAMIENTO DE LA PSICOSIS, LA ESQUIZOFRENIA Y LA ANSIEDAD. LA PRESENTE INVENCION TAMBIEN DESCRIBE PROCEDIMIENTOS PARA SU OBTENCION Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
ES9500737A 1995-04-12 1995-04-12 Nuevo compuesto derivado del cromeno. Expired - Fee Related ES2101646B1 (es)

Priority Applications (20)

Application Number Priority Date Filing Date Title
ES9500737A ES2101646B1 (es) 1995-04-12 1995-04-12 Nuevo compuesto derivado del cromeno.
ES9600323A ES2103237B1 (es) 1995-04-12 1996-02-09 Nuevo compuesto derivado del cromeno.
TW085103637A TW353071B (en) 1995-04-12 1996-03-22 Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
IL11764696A IL117646A (en) 1995-04-12 1996-03-25 7-¬3-¬4-(6-fluoro-1,2-benzisoxazole-3-YL)piperidin-1-YL¾propoxy¾3-alkyl-chromen-4-ones their preparation their uses and pharmaceutical compositions comprising them
ZA962391A ZA962391B (en) 1995-04-12 1996-03-26 Chromene compounds
MX9601163A MX9601163A (es) 1995-04-12 1996-03-28 Nuevos compuestos derivados de cromeno.
EP96912012A EP0765323B1 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
NZ306447A NZ306447A (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives; medicaments
JP53071696A JP3916662B2 (ja) 1995-04-12 1996-04-11 ４−（６−フルオロ−１，２−ベンズイソオキサゾリル）−１−ピペリジニル−プロポキシ−クロメン−４−オン誘導体、その製造、ならびに精神病、精神分裂症、および不安症の治療におけるその使用
DK96912012T DK0765323T3 (da) 1995-04-12 1996-04-11 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinylpropoxychromen-4-onderivater, deres fremstilling og deres anvendelse til behandling af psykose, skizofreni og angst
KR1019960707131A KR100396474B1 (ko) 1995-04-12 1996-04-11 정신병,정신분열증및정신불안치료에사용하는4-(6-플루오르-1,2-벤즈이소옥사조릴)-1-피페리디닐-프로폭시-크로멘-4-온유도체,그유도체에의한조제학적조성물및그제조방법
AU55004/96A AU696494B2 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy -chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
PCT/EP1996/001551 WO1996032389A1 (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
DE69613783T DE69613783T2 (de) 1995-04-12 1996-04-11 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen
US08/750,790 US5736558A (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1 piperidinyl-propoxy-chromen-4-one-one-derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
PT96912012T PT765323E (pt) 1995-04-12 1996-04-11 Derivados de 4-(6-fluoro-1,2-benzisoxazolil)-1-piperidinil-propoxicromen-4-ona, sua preparacao e sua utilizacao no tratamentoda psicose, esquizofrenia e ansiedade
AT96912012T ATE203022T1 (de) 1995-04-12 1996-04-11 4-(6-fluor-1,2-benzisoxazolyl)-1-piperidinyl- propoxy-chromen-4-on-derivate,ihre herstellung und ihre verwendung in der behandlung von psychosen, schizophrenie und angstzuständen
CA002192596A CA2192596C (en) 1995-04-12 1996-04-11 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety
NO965300A NO307517B1 (no) 1995-04-12 1996-12-11 4-(6-fluor-1,2-benzisoksazolyl)-1-piperidinyl-propoksy-kromen- 4-on-derivater, farmasøytisk preparat inneholdende slike derivater, og deres anvendelse
GR20010401686T GR3036825T3 (en) 1995-04-12 2001-10-08 4-(6-fluoro-1,2-benzisoxazolyl)-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis, schizophrenia and anxiety

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9500737A ES2101646B1 (es) 1995-04-12 1995-04-12 Nuevo compuesto derivado del cromeno.

Publications (2)

Publication Number Publication Date
ES2101646A1 true ES2101646A1 (es) 1997-07-01
ES2101646B1 ES2101646B1 (es) 1998-04-01

Family

ID=8290091

Family Applications (2)

Application Number Title Priority Date Filing Date
ES9500737A Expired - Fee Related ES2101646B1 (es) 1995-04-12 1995-04-12 Nuevo compuesto derivado del cromeno.
ES9600323A Expired - Fee Related ES2103237B1 (es) 1995-04-12 1996-02-09 Nuevo compuesto derivado del cromeno.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES9600323A Expired - Fee Related ES2103237B1 (es) 1995-04-12 1996-02-09 Nuevo compuesto derivado del cromeno.

Country Status (4)

Country Link
KR (1) KR100396474B1 (es)
ES (2) ES2101646B1 (es)
TW (1) TW353071B (es)
ZA (1) ZA962391B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2154176B1 (es) * 1998-09-21 2001-10-16 Ferrer Int Nuevo procedimiento de obtencion de 3-(hidroximetil)cromen-4-onas.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
EP0402644A1 (en) * 1989-05-19 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-(aryloxyalkyl)heteroarylpiperidines and -heteroarylpiperazines,a process for their preparation and their use as medicaments
EP0428437A1 (fr) * 1989-11-07 1991-05-22 Adir Et Compagnie Dérivés du 1,2-benzisoxazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2074966B1 (es) * 1994-02-11 1996-06-16 Vita Invest Sa Procedimiento para la obtencion de 3-(2-(4-(6-fluoro-benzo(d)isoxazol-3-il)piperidin-1-il)-etil)-2-metil-6,7,8,9-tetrahidro-4h-pirido-(1,2-a)pirimidin-4-ona.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190015A1 (en) * 1985-01-30 1986-08-06 Warner-Lambert Company Novel 4H-1-benzopyran-4-ones and their sulphur containing analogs
EP0402644A1 (en) * 1989-05-19 1990-12-19 Hoechst-Roussel Pharmaceuticals Incorporated N-(aryloxyalkyl)heteroarylpiperidines and -heteroarylpiperazines,a process for their preparation and their use as medicaments
EP0428437A1 (fr) * 1989-11-07 1991-05-22 Adir Et Compagnie Dérivés du 1,2-benzisoxazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAEN, J.C. et al.: "Dopamine autoreceptor agonists as potential antipsychotics. 2 (Aminoalkoxy)-4H-1-benzopyran-4-ones". J. Med. Chem. Vol. 34, 1991, pßginas 248-256 * Tabla I * *

Also Published As

Publication number Publication date
ES2103237A1 (es) 1997-09-01
TW353071B (en) 1999-02-21
ES2103237B1 (es) 1998-06-16
ES2101646B1 (es) 1998-04-01
KR100396474B1 (ko) 2003-11-28
ZA962391B (en) 1997-03-12

Similar Documents

Publication Publication Date Title
PL315059A1 (en) 5-(2-imidazolynynamino) benzimidazole derivatives, method of obtaining them and their application as antagonists of a-2-andrenoceptors
IL142649A0 (en) Azole derivatives
NZ504106A (en) Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them
WO1999008501A3 (en) New heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
EP0896533A4 (en) PENTAFLUOROBENZEN SULPHONAMIDES AND ANALOGS
IL101819A0 (en) Amidinophenylalanine derivatives,a process for the preparation thereof,use thereof and agents containing these as anticoagulants
ES2158537T3 (es) Derivados de acidos ciclopropilalcanoicos.
ES2153975T3 (es) Derivados de pirimidona con actividad antifungica.
IL156967A0 (en) Camptothecin derivatives
GR3019490T3 (en) Substituted piperazines as central nervous system agents
IL123776A0 (en) Novel derivatives of cyclodepsipeptide PF 1022
YU75101A (sh) Supstituisani biciklični heterocikli, postupak njihove izrade i njihova upotreba kao antigojaznih i hipoholesterolemijskih agenasa
ES2104509A1 (es) Nuevos compuestos derivados de 2-(3,4-disustituido-1-piperazinil)-5-fluoropirimidina.
DE69917005D1 (de) Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung
PL308635A1 (en) Glucopyranosidic derivatives of bezothiophenols, pharmaceutical compositions containing them and method of obtaining such derivatives
DE69330601D1 (de) Serotoninergische ergolin derivate
MY130757A (en) Bicyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
ES2101646A1 (es) Nuevo compuesto derivado del cromeno.
GR3023757T3 (en) Cyclic benzylamino, benzylamido and benzylimido derivatives as antipsychotic agents.
HUT61769A (en) Process for producing new spirocyclopropyl-cephalosporin derivatives and pharmaceutical compositions containing them
EP0276805A3 (en) Substituted 3-phenyl-7h-thiazoloû3,2-b¨û1,2,4¨triazin-7-ones, processes for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds
ES2101620A1 (es) Nuevo compuesto derivado del cromeno.
EP0828749A4 (en) COMPOSITIONS AND METHODS FOR SYNTHESIS OF ORGANOPHOSPHOROUS DERIVATIVES
IL117083A (en) Pyridine and pyridazine derivatives processes for the production thereof and pharmaceutical compositions containing these compounds
WO2000068209A3 (en) 1,5-benzodiazepine derivatives as cck-a receptor agonists

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19970701

Kind code of ref document: A1

Effective date: 19970701

FD2A Announcement of lapse in spain

Effective date: 20180806