FI96026B - Menetelmä terapeuttisesti tehokkaiden 4(5)-asemassa bisyklisellä ryhmällä substituoitujen imidatsolien valmistamiseksi - Google Patents
Menetelmä terapeuttisesti tehokkaiden 4(5)-asemassa bisyklisellä ryhmällä substituoitujen imidatsolien valmistamiseksiInfo
- Publication number
- FI96026B FI96026B FI895325A FI895325A FI96026B FI 96026 B FI96026 B FI 96026B FI 895325 A FI895325 A FI 895325A FI 895325 A FI895325 A FI 895325A FI 96026 B FI96026 B FI 96026B
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- therapeutically effective
- bicyclic group
- hal
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8828831 | 1988-12-09 | ||
GB8828831A GB2225782A (en) | 1988-12-09 | 1988-12-09 | Imidazole derivatives useful for treatment of diabetes |
Publications (3)
Publication Number | Publication Date |
---|---|
FI895325A0 FI895325A0 (fi) | 1989-11-09 |
FI96026B true FI96026B (fi) | 1996-01-15 |
FI96026C FI96026C (fi) | 1996-04-25 |
Family
ID=10648267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI895325A FI96026C (fi) | 1988-12-09 | 1989-11-09 | Menetelmä terapeuttisesti tehokkaiden 4(5)-asemassa bisyklisellä ryhmällä substituoitujen imidatsolien valmistamiseksi |
Country Status (22)
Country | Link |
---|---|
US (1) | US5292887A (fi) |
EP (1) | EP0372954B1 (fi) |
JP (1) | JP2868813B2 (fi) |
KR (1) | KR900009605A (fi) |
CN (1) | CN1023219C (fi) |
AT (1) | ATE102608T1 (fi) |
AU (1) | AU619928B2 (fi) |
CA (1) | CA2004799A1 (fi) |
DD (1) | DD290880A5 (fi) |
DE (1) | DE68913673T2 (fi) |
DK (1) | DK603789A (fi) |
ES (1) | ES2052937T3 (fi) |
FI (1) | FI96026C (fi) |
GB (1) | GB2225782A (fi) |
HU (1) | HU205086B (fi) |
IE (1) | IE61870B1 (fi) |
IL (1) | IL92609A0 (fi) |
NO (1) | NO177138C (fi) |
NZ (1) | NZ231649A (fi) |
PT (1) | PT92515B (fi) |
RU (2) | RU1831479C (fi) |
ZA (1) | ZA899366B (fi) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI862039A0 (fi) * | 1986-05-15 | 1986-05-15 | Farmos Oy | Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat. |
GB9127050D0 (en) * | 1991-12-20 | 1992-02-19 | Orion Yhtymae Oy | Substituted imidazole derivatives and their preparation and use |
GB9312669D0 (en) | 1993-06-18 | 1993-08-04 | Orion Yhtymae Oy | New opticla isomers |
FR2735776B1 (fr) * | 1995-06-22 | 1997-07-18 | Synthelabo | Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique |
EP1147092A1 (en) * | 1999-01-18 | 2001-10-24 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
US6388090B2 (en) | 2000-01-14 | 2002-05-14 | Orion Corporation | Imidazole derivatives |
FI20000073A0 (fi) * | 2000-01-14 | 2000-01-14 | Orion Yhtymae Oy | Uusia imidatsolijohdannaisia |
PE20011321A1 (es) * | 2000-05-08 | 2002-01-03 | Orion Corp | Indanilimizadoles policiclicos nuevos con actividad adrenergica alfa 2 |
US8188126B2 (en) | 2002-05-16 | 2012-05-29 | Pierre Fabre Medicament | Imidazolic compounds and use thereof as alpha-2 adrenergic receptors |
FR2839719B1 (fr) * | 2002-05-16 | 2004-08-06 | Pf Medicament | Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments |
GB0226076D0 (en) * | 2002-11-08 | 2002-12-18 | Rp Scherer Technologies Inc | Improved formulations containing substituted imidazole derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
FI81092C (fi) * | 1986-05-15 | 1990-09-10 | Farmos Oy | Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat. |
-
1988
- 1988-12-09 GB GB8828831A patent/GB2225782A/en not_active Withdrawn
-
1989
- 1989-11-09 FI FI895325A patent/FI96026C/fi not_active IP Right Cessation
- 1989-11-16 NO NO894563A patent/NO177138C/no not_active IP Right Cessation
- 1989-11-30 DK DK603789A patent/DK603789A/da not_active Application Discontinuation
- 1989-12-06 CA CA002004799A patent/CA2004799A1/en not_active Abandoned
- 1989-12-06 US US07/446,839 patent/US5292887A/en not_active Expired - Fee Related
- 1989-12-06 NZ NZ231649A patent/NZ231649A/xx unknown
- 1989-12-06 AU AU45992/89A patent/AU619928B2/en not_active Ceased
- 1989-12-07 DE DE68913673T patent/DE68913673T2/de not_active Expired - Fee Related
- 1989-12-07 EP EP89312755A patent/EP0372954B1/en not_active Expired - Lifetime
- 1989-12-07 ZA ZA899366A patent/ZA899366B/xx unknown
- 1989-12-07 PT PT92515A patent/PT92515B/pt not_active IP Right Cessation
- 1989-12-07 IE IE392689A patent/IE61870B1/en not_active IP Right Cessation
- 1989-12-07 KR KR1019890018116A patent/KR900009605A/ko not_active Application Discontinuation
- 1989-12-07 DD DD89335371A patent/DD290880A5/de not_active IP Right Cessation
- 1989-12-07 ES ES89312755T patent/ES2052937T3/es not_active Expired - Lifetime
- 1989-12-07 AT AT89312755T patent/ATE102608T1/de not_active IP Right Cessation
- 1989-12-08 JP JP1320387A patent/JP2868813B2/ja not_active Expired - Fee Related
- 1989-12-08 IL IL92609A patent/IL92609A0/xx unknown
- 1989-12-08 RU SU4742612A patent/RU1831479C/ru active
- 1989-12-08 CN CN89109220A patent/CN1023219C/zh not_active Expired - Fee Related
- 1989-12-08 HU HU896481A patent/HU205086B/hu not_active IP Right Cessation
-
1991
- 1991-01-08 RU SU91A patent/RU1833375C/ru active
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
MM | Patent lapsed |
Owner name: FARMOS-YHTYMAE OY |