FI956261A - Jodattu neurokoetin monoamiinin takaisinottokohtien kartoittamiseksi - Google Patents

Jodattu neurokoetin monoamiinin takaisinottokohtien kartoittamiseksi Download PDF

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Publication number
FI956261A
FI956261A FI956261A FI956261A FI956261A FI 956261 A FI956261 A FI 956261A FI 956261 A FI956261 A FI 956261A FI 956261 A FI956261 A FI 956261A FI 956261 A FI956261 A FI 956261A
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FI
Finland
Prior art keywords
group
isotope
cnh2n
neurotestor
iodized
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Application number
FI956261A
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English (en)
Swedish (sv)
Other versions
FI120183B (fi
FI956261A0 (fi
Inventor
John L Neumeyer
Richard A Milius
Robert B Innis
Original Assignee
Res Biochemicals Limited Partn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of FI956261A publication Critical patent/FI956261A/fi
Publication of FI956261A0 publication Critical patent/FI956261A0/fi
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Publication of FI120183B publication Critical patent/FI120183B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
FI956261A 1992-02-25 1995-12-27 Jodattu neurokoetin monoamiinin takaisinottokohtien kartoittamiseksi FI120183B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84161792 1992-02-25
US07/841,617 US5310912A (en) 1992-02-25 1992-02-25 Iodinated neuroprobe for mapping monoamine reuptake sites
PCT/US1993/006170 WO1995001184A1 (en) 1992-02-25 1993-06-29 An iodinated neuroprobe for mapping monoamine reuptake sites
US9306170 1993-06-29

Publications (3)

Publication Number Publication Date
FI956261A true FI956261A (fi) 1995-12-27
FI956261A0 FI956261A0 (fi) 1995-12-27
FI120183B FI120183B (fi) 2009-07-31

Family

ID=25285315

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956261A FI120183B (fi) 1992-02-25 1995-12-27 Jodattu neurokoetin monoamiinin takaisinottokohtien kartoittamiseksi

Country Status (12)

Country Link
US (2) US5310912A (fi)
EP (1) EP0703791B1 (fi)
JP (1) JP3228422B2 (fi)
AT (1) ATE228858T1 (fi)
AU (1) AU674331B2 (fi)
DE (2) DE10399020I2 (fi)
DK (1) DK0703791T3 (fi)
ES (1) ES2189792T3 (fi)
FI (1) FI120183B (fi)
NL (1) NL300123I2 (fi)
PT (1) PT703791E (fi)
WO (1) WO1995001184A1 (fi)

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US5496953A (en) * 1990-08-09 1996-03-05 Research Triangle Institute Cocaine receptor binding ligands
US5736123A (en) * 1990-08-09 1998-04-07 Research Triangle Institute Cocaine receptor binding ligands
US5128118A (en) * 1990-08-09 1992-07-07 Research Triangle Institute Cocaine receptor binding ligands
US7189737B2 (en) 1991-08-09 2007-03-13 Research Triangle Institute Cocaine receptor binding ligands
US5750089A (en) * 1996-01-11 1998-05-12 Neuro Imaging Technologies, Llc Halogenated neuroprobe for mapping monoamine reuptake sites
US5770180A (en) * 1992-08-24 1998-06-23 Organix, Inc. Bridge-substituted tropanes for methods of imaging and therapy
US5493026A (en) * 1993-10-25 1996-02-20 Organix, Inc. Substituted 2-carboxyalkyl-3-(fluorophenyl)-8-(3-halopropen-2-yl) nortropanes and their use as imaging for agents for neurodegenerative disorders
WO1996039198A1 (en) 1995-06-06 1996-12-12 RESEARCH BIOCHEMICALS, LIMITED PARTNERSHIP, doing business as RESEARCH BIOCHEMICALS INTERNATIONAL, A MASSACHUSETTS LIMITED PARTNERSHIP, WHOSE SOLE GENERAL PARTNER IS RBI MANAGEMENT, INC. Iodinated neuroprobes for mapping monoamine reuptake sites
US5864038A (en) * 1995-08-17 1999-01-26 Emory University Labeled cocaine analogs
US6171576B1 (en) * 1995-11-03 2001-01-09 Organix Inc. Dopamine transporter imaging agent
US7105678B2 (en) 1995-11-03 2006-09-12 Organix, Inc. Boat tropanes
US5948933A (en) 1997-07-11 1999-09-07 Organix, Inc. Tropane analogs and methods for inhibition of monoamine transport
FR2748475B1 (fr) * 1996-05-10 1999-04-16 Cis Bio Int Derives du tropane utilisables en particulier pour la detection in vivo des transporteurs de la dopamine
JP2001503412A (ja) * 1996-10-29 2001-03-13 ギルフォード ファーマシューティカルズ インコーポレイテッド 放射性薬剤の製造方法
FI104048B1 (fi) * 1997-06-16 1999-11-15 Map Medical Technologies Oy Prosessi tuottaa radiojodattuja reseptoriaineita in vivo käyttöön
US6358492B1 (en) * 1997-10-07 2002-03-19 Research Triangle Institute Dopamine transporter imaging ligand
US6013242A (en) * 1998-01-13 2000-01-11 Wake Forest University Tropane derivatives with selective binding to the serotonin reuptake transporters for treatment of mental illness and as intermediates in the formation of imaging diagnostic agents for depression
US6843979B2 (en) 1999-04-26 2005-01-18 Emory University 4-haloethenylphenyl tropane:serotonin transporter imaging agents
DE60015576T2 (de) * 1999-04-26 2005-11-10 Emory University 4-Fluoralkyl-3-halogenphenylnortropane
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
KR20040100835A (ko) * 2001-02-15 2004-12-02 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법
MXPA03006524A (es) * 2001-02-16 2003-09-25 Aventis Pharma Inc Derivados heterociclicos novedosos de amidas y su uso como ligandos para receptor d3 de dopamina.
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
DE20120708U1 (de) 2001-10-09 2002-08-01 Meltzer Peter C Tropan-Analoga zur Inhibierung des Monoamin-Transports
US20030190350A1 (en) * 2001-10-29 2003-10-09 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
DK1499584T3 (da) * 2002-04-30 2010-09-20 Univ Emory Forbindelser til tumorbilleddannelse
JP2005154374A (ja) * 2003-11-27 2005-06-16 Hamamatsu Photonics Kk 放射性トロパンアルカロイド誘導体、トロパンアルカロイド誘導体、及びそれらの製造方法。
US20060292073A1 (en) * 2005-06-23 2006-12-28 Emory University Stereoselective Synthesis of Amino Acid Analogs for Tumor Imaging
EP1893244A4 (en) * 2005-06-23 2009-06-24 Univ Emory CONTRAST AGENTS
EP2212319B1 (en) 2007-10-31 2018-07-18 Alseres Pharmaceuticals, Inc. Labeled iodinated tropane formulation
US8246752B2 (en) 2008-01-25 2012-08-21 Clear Catheter Systems, Inc. Methods and devices to clear obstructions from medical tubes
CN110582494A (zh) * 2017-03-17 2019-12-17 日本医事物理股份有限公司 碘氟潘的制造方法
EP3880674A1 (en) 2020-01-24 2021-09-22 Rotop Radiopharmacy Gmbh Method for the preparation of n-monofluoroalkyl tropanes and their use

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US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
US4942231A (en) * 1984-05-24 1990-07-17 Mallinckrodt, Inc. Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
US5098996A (en) * 1984-10-26 1992-03-24 The United States Of America As Represented By The Department Of Health And Human Services Process for introducing fluorine into biologically active materials
US5200169A (en) * 1987-04-16 1993-04-06 Neorx Corporation Vinyl substituted radiohalogen conjugates for protein labeling
US5186921A (en) * 1989-04-17 1993-02-16 Trustees Of The University Of Pennsylvania Dopamine receptor ligands and image agents
US5128118A (en) * 1990-08-09 1992-07-07 Research Triangle Institute Cocaine receptor binding ligands
US5104638A (en) * 1990-10-29 1992-04-14 Mallinckrodt Medical, Inc. Method of making a radiopharmaceutical complex from a kit

Also Published As

Publication number Publication date
DE10399020I1 (de) 2003-09-18
ATE228858T1 (de) 2002-12-15
DK0703791T3 (da) 2003-03-24
WO1995001184A1 (en) 1995-01-12
AU674331B2 (en) 1996-12-19
JPH09503745A (ja) 1997-04-15
FI120183B (fi) 2009-07-31
DE10399020I2 (de) 2005-05-04
NL300123I2 (nl) 2003-08-01
US5439666A (en) 1995-08-08
DE69332544T2 (de) 2003-08-14
DE69332544D1 (de) 2003-01-16
EP0703791A4 (en) 1996-05-22
EP0703791A1 (en) 1996-04-03
US5310912A (en) 1994-05-10
PT703791E (pt) 2003-04-30
ES2189792T3 (es) 2003-07-16
NL300123I1 (nl) 2003-06-02
AU4655493A (en) 1995-01-24
EP0703791B1 (en) 2002-12-04
JP3228422B2 (ja) 2001-11-12
FI956261A0 (fi) 1995-12-27

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