FI950169A0 - PTH:n ja PTHRP:n analogit, niiden synteesi ja käyttö osteoporoosin hoitoon - Google Patents

PTH:n ja PTHRP:n analogit, niiden synteesi ja käyttö osteoporoosin hoitoon

Info

Publication number
FI950169A0
FI950169A0 FI950169A FI950169A FI950169A0 FI 950169 A0 FI950169 A0 FI 950169A0 FI 950169 A FI950169 A FI 950169A FI 950169 A FI950169 A FI 950169A FI 950169 A0 FI950169 A0 FI 950169A0
Authority
FI
Finland
Prior art keywords
laa
haa
pth
pthrp
treatment
Prior art date
Application number
FI950169A
Other languages
English (en)
Swedish (sv)
Other versions
FI120586B (fi
FI950169A (fi
Inventor
John L Krstenansky
Jr John J Nestor
Teresa H Ho
Brian H Vickery
Chinh T Bach
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of FI950169A0 publication Critical patent/FI950169A0/fi
Publication of FI950169A publication Critical patent/FI950169A/fi
Application granted granted Critical
Publication of FI120586B publication Critical patent/FI120586B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI950169A 1992-07-14 1995-01-13 Menetelmä PTH:n ja PTHRP:n analogien valmistamiseksi, ja niiden käyttö osteoporoosin hoitoon FI120586B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/915,247 US5589452A (en) 1992-07-14 1992-07-14 Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US91524792 1992-07-14
US9306465 1993-07-13
PCT/US1993/006465 WO1994001460A1 (en) 1992-07-14 1993-07-13 Analogs of pth and pthrp, their synthesis and use for the treatment of osteoporosis

Publications (3)

Publication Number Publication Date
FI950169A0 true FI950169A0 (fi) 1995-01-13
FI950169A FI950169A (fi) 1995-01-13
FI120586B FI120586B (fi) 2009-12-15

Family

ID=25435450

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950169A FI120586B (fi) 1992-07-14 1995-01-13 Menetelmä PTH:n ja PTHRP:n analogien valmistamiseksi, ja niiden käyttö osteoporoosin hoitoon

Country Status (17)

Country Link
US (8) US5589452A (fi)
EP (2) EP1094073A3 (fi)
JP (1) JP4106082B2 (fi)
KR (3) KR100461618B1 (fi)
AT (1) ATE202115T1 (fi)
AU (1) AU671851B2 (fi)
CA (1) CA2140281C (fi)
DE (1) DE69330347T2 (fi)
DK (1) DK0651765T3 (fi)
ES (1) ES2159293T3 (fi)
FI (1) FI120586B (fi)
GR (1) GR3036521T3 (fi)
HU (2) HU217843B (fi)
MX (1) MX9304226A (fi)
NZ (1) NZ254554A (fi)
PT (1) PT651765E (fi)
WO (1) WO1994001460A1 (fi)

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US5589452A (en) 1996-12-31
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GR3036521T3 (en) 2001-12-31
DE69330347T2 (de) 2002-05-29
AU671851B2 (en) 1996-09-12
KR100461618B1 (ko) 2005-04-06
ES2159293T3 (es) 2001-10-01
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KR100404008B1 (ko) 2003-11-01
EP0651765A1 (en) 1995-05-10
ATE202115T1 (de) 2001-06-15
HU211348A9 (en) 1995-11-28
JP4106082B2 (ja) 2008-06-25
CA2140281A1 (en) 1994-01-20
US5798225A (en) 1998-08-25
HU9500110D0 (en) 1995-03-28
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US5807823A (en) 1998-09-15
US5695955A (en) 1997-12-09
FI950169A (fi) 1995-01-13
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CA2140281C (en) 2002-06-25
US6051686A (en) 2000-04-18
US5874086A (en) 1999-02-23
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NZ254554A (en) 1996-03-26
MX9304226A (es) 1995-01-31
EP1094073A2 (en) 2001-04-25
AU4670593A (en) 1994-01-31
PT651765E (pt) 2001-11-30
KR950702578A (ko) 1995-07-29
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US5693616A (en) 1997-12-02
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