FI940904A7 - Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö - Google Patents

Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö Download PDF

Info

Publication number
FI940904A7
FI940904A7 FI940904A FI940904A FI940904A7 FI 940904 A7 FI940904 A7 FI 940904A7 FI 940904 A FI940904 A FI 940904A FI 940904 A FI940904 A FI 940904A FI 940904 A7 FI940904 A7 FI 940904A7
Authority
FI
Finland
Prior art keywords
preparation
oxazolidinedione derivatives
oxazolidinedione
derivatives
Prior art date
Application number
FI940904A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI940904L (fi
FI940904A0 (fi
Inventor
Sachiko Imai
Yu Momose
Hitoshi Ideda
Takashi Sohda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI940904A0 publication Critical patent/FI940904A0/fi
Publication of FI940904L publication Critical patent/FI940904L/fi
Publication of FI940904A7 publication Critical patent/FI940904A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
FI940904A 1993-02-26 1994-02-25 Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö FI940904A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3823693 1993-02-26
JP19730493 1993-08-09

Publications (3)

Publication Number Publication Date
FI940904A0 FI940904A0 (fi) 1994-02-25
FI940904L FI940904L (fi) 1994-11-29
FI940904A7 true FI940904A7 (fi) 1994-11-29

Family

ID=26377445

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940904A FI940904A7 (fi) 1993-02-26 1994-02-25 Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö

Country Status (18)

Country Link
US (4) US5665748A (cg-RX-API-DMAC7.html)
EP (1) EP0612743B1 (cg-RX-API-DMAC7.html)
JP (2) JP3328720B2 (cg-RX-API-DMAC7.html)
KR (1) KR940019699A (cg-RX-API-DMAC7.html)
CN (1) CN1098411A (cg-RX-API-DMAC7.html)
AT (1) ATE157975T1 (cg-RX-API-DMAC7.html)
AU (1) AU673034B2 (cg-RX-API-DMAC7.html)
CA (1) CA2116387C (cg-RX-API-DMAC7.html)
DE (1) DE69405425T2 (cg-RX-API-DMAC7.html)
DK (1) DK0612743T3 (cg-RX-API-DMAC7.html)
ES (1) ES2108375T3 (cg-RX-API-DMAC7.html)
FI (1) FI940904A7 (cg-RX-API-DMAC7.html)
GR (1) GR3025342T3 (cg-RX-API-DMAC7.html)
HU (1) HUT70159A (cg-RX-API-DMAC7.html)
NO (1) NO305079B1 (cg-RX-API-DMAC7.html)
PH (1) PH31468A (cg-RX-API-DMAC7.html)
RU (1) RU2126797C1 (cg-RX-API-DMAC7.html)
TW (1) TW268952B (cg-RX-API-DMAC7.html)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468762A (en) * 1994-05-18 1995-11-21 American Home Products Corporation Azolidinediones as antihyperglycemic agents
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
CA2171702A1 (en) * 1995-03-14 1996-09-15 Takashi Sohda Benzofuran compounds and their use
JPH09136877A (ja) * 1995-06-16 1997-05-27 Takeda Chem Ind Ltd 複素環化合物、その製造法及び用途
WO1997036882A1 (en) 1996-04-03 1997-10-09 Takeda Chemical Industries, Ltd. Oxazole derivatives, their production and use
JPH09323930A (ja) * 1996-04-04 1997-12-16 Takeda Chem Ind Ltd 悪液質の予防・治療剤
US5889032A (en) * 1996-05-06 1999-03-30 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
FR2749583B1 (fr) 1996-06-07 1998-08-21 Lipha Nouveaux derives de thiazolidine -2,4- dione substitues, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
KR100579765B1 (ko) 1996-07-01 2006-12-28 닥터 레디스 레보러터리즈 리미티드 신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
AU740444B2 (en) 1996-08-19 2001-11-01 Japan Tobacco Inc. Propionic acid derivatives and use thereof
US6011036A (en) * 1997-04-15 2000-01-04 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
US6011031A (en) * 1997-05-30 2000-01-04 Dr. Reddy's Research Foundation Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
ATE274510T1 (de) 1998-06-19 2004-09-15 Chiron Corp Glycogen synthase kinase 3 inhibitoren
CN1053186C (zh) * 1998-07-09 2000-06-07 华东理工大学 喹啉噁唑啉化合物
JP2000044551A (ja) * 1998-07-27 2000-02-15 Konica Corp ３−置換−３−オキソ−２−（２，４−オキサゾリジンジオン−３−イル）プロピオン酸アミド化合物の製造方法
AU6331199A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders
US6121300A (en) * 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
IL143299A0 (en) * 1998-12-01 2002-04-21 Novo Nordisk As Pharmaceutical composition comprising 5-[[4- [3-methyl-4-oxo-3, 4-dihydro-2-quinazolinyl] methoxy] phenyl-methyl] thiadiazolidine-2, 4-dione and the process for its preparation
HK1039940B (en) 1999-04-07 2010-08-27 Sankyo Company, Limited Amine derivatives
US6380191B1 (en) 1999-06-18 2002-04-30 Merck & Co. Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
JP2003502369A (ja) 1999-06-18 2003-01-21 メルク エンド カムパニー インコーポレーテッド アリールチアゾリジンジオン誘導体およびアリールオキサゾリジンジオン誘導体
GB9914977D0 (en) 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
JP4316787B2 (ja) * 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、
US7105551B2 (en) 2000-12-20 2006-09-12 Smithkline Beecham Corporation Thiazole derivatives for treating PPAR related disorders
EP1394154A4 (en) * 2001-03-23 2005-05-18 Takeda Pharmaceutical FIVE-GLASS HETEROCYCLIC ALKANIC ACID DERIVATIVE
TW200300681A (en) * 2001-11-12 2003-06-16 Ono Pharmaceutical Co Carboxylic acid derivative compound and medicament containing same as active ingredient
AU2003203170A1 (en) * 2002-01-17 2003-07-30 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
TWI327462B (en) * 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
KR20060006953A (ko) 2003-04-30 2006-01-20 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 카르복실산
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
DK1709014T3 (da) * 2004-01-20 2007-09-10 Merck & Co Inc Antidiabetiske oxazolidindioner og thiazolidindioner
JP2008518926A (ja) * 2004-10-28 2008-06-05 ジ インスティチューツ フォー ファーマシューティカル ディスカバリー、エルエルシー 置換フェニルアルカン酸
TW200932219A (en) * 2007-10-24 2009-08-01 Astellas Pharma Inc Oxadiazolidinedione compound

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US5232925A (en) * 1987-09-04 1993-08-03 Beecham Group P.L.C. Compounds
FI904414A7 (fi) * 1988-03-08 1990-09-07 Pfizer Tiatsolidiinidioni-hypoglykeemisesti vaikuttavat aineet
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
JP2991801B2 (ja) * 1990-04-27 1999-12-20 三共株式会社 ベンジリデンチアゾリジン化合物
US5037842A (en) 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
EP0579733B1 (en) * 1991-04-11 2001-06-20 PHARMACIA & UPJOHN COMPANY Thiazolidinedione derivatives, production and use thereof
WO1993003021A1 (fr) * 1991-07-30 1993-02-18 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive bisheterocyclique ou son sel
JPH05202042A (ja) * 1992-01-24 1993-08-10 Sankyo Co Ltd 糖尿病性合併症治療剤
FI935920A7 (fi) * 1992-04-30 1993-12-29 Taiho Pharmaceutical Co Ltd Oksatsolidiinijohdannaiset ja niiden farmaseuttisesti hyväksyttävät suolat
US5928152A (en) * 1994-08-05 1999-07-27 Acuson Corporation Method and apparatus for a baseband processor of a receive beamformer system

Also Published As

Publication number Publication date
ATE157975T1 (de) 1997-09-15
US5665748A (en) 1997-09-09
JPH07165735A (ja) 1995-06-27
CA2116387C (en) 2003-12-23
PH31468A (en) 1998-11-03
FI940904L (fi) 1994-11-29
RU2126797C1 (ru) 1999-02-27
CN1098411A (zh) 1995-02-08
NO305079B1 (no) 1999-03-29
EP0612743B1 (en) 1997-09-10
AU673034B2 (en) 1996-10-24
HU9400578D0 (en) 1994-05-30
JP2000191651A (ja) 2000-07-11
ES2108375T3 (es) 1997-12-16
EP0612743A1 (en) 1994-08-31
US5972970A (en) 1999-10-26
KR940019699A (ko) 1994-09-14
HUT70159A (en) 1995-09-28
GR3025342T3 (en) 1998-02-27
FI940904A0 (fi) 1994-02-25
DE69405425D1 (de) 1997-10-16
DK0612743T3 (da) 1998-04-20
CA2116387A1 (en) 1994-08-27
NO940610D0 (no) 1994-02-23
AU5515894A (en) 1994-09-01
DE69405425T2 (de) 1998-03-19
NO940610L (no) 1994-08-29
TW268952B (cg-RX-API-DMAC7.html) 1996-01-21
US6552058B1 (en) 2003-04-22
US6147099A (en) 2000-11-14
JP3328720B2 (ja) 2002-09-30

Similar Documents

Publication Publication Date Title
FI940904A7 (fi) Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI955235A0 (fi) Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
FI945281A7 (fi) Heterosykliset yhdisteet, niiden valmistus ja käyttö
FI20000516A7 (fi) Bis-indolyylimaleimidijohdannaiset ja niiden valmistus
FI941378L (fi) Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
FI931901A7 (fi) Atsoliyhdisteet, niiden valmistus ja käyttö
FI934426A7 (fi) Tiatsolidiinidionijohdokset, niiden valmistus ja käyttö
FI935887L (fi) Tiatzolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI943912A7 (fi) Tienopyrimidiinijohdannaiset, niiden valmistus ja käyttö
FI935897L (fi) Pyridopyrimidiinijohdannaiset, niiden valmistus ja käyttö
FI962043L (fi) Substituoidut 5-rengas-heterosyklit, niiden valmistus ja niiden käyttö
FI944417L (fi) Atsoliyhdisteet, niiden valmistus ja käyttö
FI941287L (fi) Triatsolokinoksalin-1,4-dioneja ja niiden valmistus ja käyttö
FI941068A7 (fi) Bentsoksatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI970997L (fi) Bentsosykloalkeeniyhdisteet, niiden valmistus ja käyttö
FI934680A7 (fi) Aryylimorfoliini, valmistus ja käyttö
FI954229L (fi) Heterosykliset yhdisteet, niiden käyttö ja valmistus
FI930716A7 (fi) Uusia aryylikarbonyyliaminoalkyylidihydro-oksopyridiinejä, niiden valmistus ja käyttö
FI944040A7 (fi) Laktolijohdannaiset, niiden valmistus ja käyttö
FI955679L (fi) Piperidiinijohdannaisia, niiden valmistus ja käyttö
FI923458A7 (fi) 4,5-sykloalkano-3-bentsatsepin-7-olijohdannaiset ja niiden käyttö
FI941963L (fi) Pyridiinijohdannaiset, niiden valmistus ja käyttö
FI971317A7 (fi) Uusia heterosyklisiä, substituoituja imidatsolokinoksalinoneja, niiden valmistus ja käyttö
FI941214L (fi) Bentsimidatsolin johdannaisia, niiden valmistus ja käyttö
FI955680L (fi) Psoraleenijohdannaiset, niiden valmistus ja käyttö