FI940192A - 2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina - Google Patents

2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina Download PDF

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Publication number
FI940192A
FI940192A FI940192A FI940192A FI940192A FI 940192 A FI940192 A FI 940192A FI 940192 A FI940192 A FI 940192A FI 940192 A FI940192 A FI 940192A FI 940192 A FI940192 A FI 940192A
Authority
FI
Finland
Prior art keywords
alkonol
hydroxypiperidino
anesthetics
derivatives
alkonol derivatives
Prior art date
Application number
FI940192A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI940192A0 (fi
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI940192A publication Critical patent/FI940192A/fi
Publication of FI940192A0 publication Critical patent/FI940192A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI940192A 1991-07-17 1994-01-14 2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina FI940192A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17
PCT/US1992/004973 WO1993002052A1 (en) 1991-07-17 1992-06-19 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (2)

Publication Number Publication Date
FI940192A true FI940192A (fi) 1994-01-14
FI940192A0 FI940192A0 (fi) 1994-01-14

Family

ID=24940103

Family Applications (2)

Application Number Title Priority Date Filing Date
FI940192A FI940192A0 (fi) 1991-07-17 1994-01-14 2-(4-hydroksipiperidino)-1-alkonolijohdannaisia verettömyyden vastaisina aineina
FI981956A FI981956A0 (fi) 1991-07-17 1998-09-11 2-(4-hydroksipiperidino)-1-alkanolijohdannaisia verettömyyden vastaisia aineina

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI981956A FI981956A0 (fi) 1991-07-17 1998-09-11 2-(4-hydroksipiperidino)-1-alkanolijohdannaisia verettömyyden vastaisia aineina

Country Status (22)

Country Link
EP (1) EP0594729A1 (zh)
JP (1) JP2571904B2 (zh)
KR (1) KR0165003B1 (zh)
CN (1) CN1043759C (zh)
AU (1) AU655840B2 (zh)
BR (1) BR9206272A (zh)
CA (1) CA2113568A1 (zh)
CZ (1) CZ284133B6 (zh)
EG (1) EG20048A (zh)
FI (2) FI940192A0 (zh)
HU (1) HUT70528A (zh)
IE (1) IE922311A1 (zh)
IL (1) IL102473A (zh)
MX (1) MX9204190A (zh)
NO (1) NO180445C (zh)
NZ (1) NZ243580A (zh)
PL (1) PL169884B1 (zh)
PT (1) PT100689B (zh)
RU (1) RU2065859C1 (zh)
TW (1) TW201732B (zh)
WO (1) WO1993002052A1 (zh)
ZA (1) ZA925306B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
CZ280669B6 (cs) * 1992-10-30 1996-03-13 Pfizer Inc. Deriváty 3,4-dihydro-2(1H)-chinolonu a farmaceutický prostředek na jejich bázi
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
CA2369695A1 (en) * 1999-04-09 2000-10-19 Manabu Itoh Agent for treating neuropathic pain
WO2001030330A2 (en) 1999-10-29 2001-05-03 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US7217716B2 (en) 2001-02-23 2007-05-15 Merck & Co., Inc. N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists
WO2002080928A1 (en) 2001-04-03 2002-10-17 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
CA2507509A1 (en) 2002-11-25 2004-06-10 Mochida Pharmaceutical Co., Ltd. Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient
JP2007508288A (ja) * 2003-10-08 2007-04-05 ファイザー株式会社 縮合ラクタム化合物
TWI409289B (zh) 2010-09-02 2013-09-21 Taiwan Union Technology Corp 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) * 1983-05-19 1985-10-25 Synthelabo Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
DK0554247T3 (da) * 1990-05-10 2000-08-07 Pfizer Neurobeskyttende indolon og beslægtede derivater

Also Published As

Publication number Publication date
IL102473A0 (en) 1993-01-14
NZ243580A (en) 1994-10-26
JPH06504293A (ja) 1994-05-19
BR9206272A (pt) 1995-04-11
ZA925306B (en) 1994-01-17
NO180445C (no) 1997-04-23
KR0165003B1 (en) 1999-01-15
MX9204190A (es) 1993-01-01
CZ284133B6 (cs) 1998-08-12
PT100689B (pt) 1999-06-30
PL169884B1 (pl) 1996-09-30
EP0594729A1 (en) 1994-05-04
HUT70528A (en) 1995-10-30
NO940144D0 (no) 1994-01-14
NO180445B (no) 1997-01-13
AU2322592A (en) 1993-02-23
HU9400136D0 (en) 1994-05-30
FI981956A (fi) 1998-09-11
IE922311A1 (en) 1993-01-27
FI981956A0 (fi) 1998-09-11
JP2571904B2 (ja) 1997-01-16
NO940144L (no) 1994-01-14
FI940192A0 (fi) 1994-01-14
WO1993002052A1 (en) 1993-02-04
CN1043759C (zh) 1999-06-23
EG20048A (en) 1997-03-27
PT100689A (pt) 1993-10-29
IL102473A (en) 1997-07-13
TW201732B (zh) 1993-03-11
CZ400892A3 (en) 1994-03-16
AU655840B2 (en) 1995-01-12
RU2065859C1 (ru) 1996-08-27
CA2113568A1 (en) 1993-02-04
CN1068566A (zh) 1993-02-03

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