FI924352A - Jontoforetiskt laekemedels frigoeringssystem - Google Patents

Jontoforetiskt laekemedels frigoeringssystem Download PDF

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Publication number
FI924352A
FI924352A FI924352A FI924352A FI924352A FI 924352 A FI924352 A FI 924352A FI 924352 A FI924352 A FI 924352A FI 924352 A FI924352 A FI 924352A FI 924352 A FI924352 A FI 924352A
Authority
FI
Finland
Prior art keywords
level
current
iontophoretic
agent
interval
Prior art date
Application number
FI924352A
Other languages
English (en)
Other versions
FI924352A0 (fi
FI110066B (fi
Inventor
Paul D Sorenson
John D Bradzinski
Gary A Lattin
Larry A Mcnichols
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27054046&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI924352(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of FI924352A publication Critical patent/FI924352A/fi
Publication of FI924352A0 publication Critical patent/FI924352A0/fi
Application granted granted Critical
Publication of FI110066B publication Critical patent/FI110066B/fi

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
FI924352A 1990-03-30 1992-09-28 Iontoforeettinen lääkeaineen luovutusjärjestelmä FI110066B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US50217690A 1990-03-30 1990-03-30
US50217690 1990-03-30
US67130691 1991-03-21
US07/671,306 US5207752A (en) 1990-03-30 1991-03-21 Iontophoretic drug delivery system with two-stage delivery profile
PCT/US1991/001941 WO1991015258A1 (en) 1990-03-30 1991-03-22 Iontophoretic drug delivery system with two-stage delivery profile
US9101941 1991-03-22

Publications (3)

Publication Number Publication Date
FI924352A true FI924352A (fi) 1992-09-28
FI924352A0 FI924352A0 (fi) 1992-09-28
FI110066B FI110066B (fi) 2002-11-29

Family

ID=27054046

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924352A FI110066B (fi) 1990-03-30 1992-09-28 Iontoforeettinen lääkeaineen luovutusjärjestelmä

Country Status (14)

Country Link
US (1) US5207752A (fi)
EP (1) EP0522092B1 (fi)
JP (1) JP3181289B2 (fi)
KR (1) KR0169084B1 (fi)
AT (1) ATE114118T1 (fi)
AU (1) AU638581B2 (fi)
CA (1) CA2079316C (fi)
DE (1) DE69105202T2 (fi)
DK (1) DK0522092T3 (fi)
ES (1) ES2067939T3 (fi)
FI (1) FI110066B (fi)
GR (1) GR3015116T3 (fi)
NO (1) NO308025B1 (fi)
WO (1) WO1991015258A1 (fi)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9206990A (es) * 1991-12-03 1993-06-01 Alza Corp Dispositivo iontoforetico de surtido y suministro de energia para el mismo.
US5505715A (en) * 1994-02-25 1996-04-09 Bristol-Myers Squibb Company Iontophoretic transdermal delivery of deoxyspergualin compounds
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5697896A (en) * 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5700481A (en) * 1995-03-17 1997-12-23 Takeda Chemical Industries, Ltd. Transdermal drug delivery process
WO1996031251A1 (de) * 1995-04-07 1996-10-10 Novartis Ag Iontophoretisches transdermales system zum verabreichen von mindestens zwei substanzen
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
AU710793B2 (en) * 1995-06-07 1999-09-30 Alza Corporation Electrotransport agent delivery method and apparatus
AU7286996A (en) * 1995-10-18 1997-05-07 Ciba-Geigy Ag Thermopile powered transdermal drug delivery device
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
WO1997048443A1 (en) * 1996-06-19 1997-12-24 Becton Dickinson And Company Iontophoretic delivery of cell adhesion inhibitors
US5857994A (en) * 1996-10-01 1999-01-12 Becton, Dickinson And Company Awakenable iontophoretic/delivery device for reducing electrical sensation upon application thereof
FR2766093B1 (fr) * 1997-07-15 1999-09-03 Lhd Lab Hygiene Dietetique Procede de commande d'un dispositif d'administration transdermique de medicament sous champ electrique
CN1154525C (zh) 1997-12-16 2004-06-23 阿尔扎有限公司 带仿真负载保持稳定给药的调节器
ATE354400T1 (de) 1997-12-17 2007-03-15 Alza Corp Iontophoretische vorrichtung mit programmierbarer elektrischer stromeinstellung
WO1999038554A1 (en) 1998-01-30 1999-08-05 Novo Nordisk A/S An injection syringe
MXPA01007996A (es) 1999-02-10 2004-03-26 Gmp Drug Delivery Inc Parches de iontoforesis, electroporacion y combinacion para entrega local de droga..
US6471675B1 (en) 1999-04-30 2002-10-29 Medtronic, Inc. Passive flow control devices for implantable pumps
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
AU2002225870B2 (en) * 2000-11-03 2006-09-21 Intarcia Therapeutics, Inc. Method for short-term and long-term drug dosimetry
KR20040053291A (ko) * 2001-11-09 2004-06-23 바이오메디신즈 인코포레이티드 오메가 인터페론을 이용한 질환 치료 방법
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US9205197B2 (en) * 2003-03-03 2015-12-08 Sanofi-Aventis Deutschland Gmbh Drug delivery device dose setting mechanism
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0308267D0 (en) * 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US7596407B2 (en) * 2004-03-26 2009-09-29 Solvay Pharmaceuticals, B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1595542A1 (en) * 2004-03-26 2005-11-16 Solvay Pharmaceuticals B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
USRE46363E1 (en) 2004-10-21 2017-04-11 Novo Nordisk A/S Dial-down mechanism for wind-up pen
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
WO2006089768A1 (en) * 2005-02-28 2006-08-31 Novo Nordisk A/S A dose setting mechanism for an injection device
US7856263B2 (en) * 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US20090043264A1 (en) 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
RU2008117167A (ru) * 2005-09-30 2009-11-10 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Способ и устройство для ионтофореза для системной доставки активных компонентов
WO2007046103A2 (en) * 2005-10-19 2007-04-26 Perf-Action Technologies Ltd. System for iontophoretic transdermal delivery of polymeric agents and methods of use thereof
JP5183499B2 (ja) 2006-03-10 2013-04-17 ノボ・ノルデイスク・エー/エス 注射装置
JP5062768B2 (ja) 2006-03-10 2012-10-31 ノボ・ノルデイスク・エー/エス 注射装置および該装置のカートリッジを交換する方法
CN104138634B (zh) * 2006-04-13 2016-09-07 梯瓦制药国际有限责任公司 递送抗偏头痛化合物的透皮方法和系统
AU2012261753B2 (en) * 2006-04-13 2015-03-05 Teva Pharmaceuticals International Gmbh Transdermal methods and systems for the delivery of anti-migraine compounds
DE602007004972D1 (de) 2006-05-16 2010-04-08 Novo Nordisk As Getriebemechanismus für ein injektionsgerät
US7954624B2 (en) * 2006-05-16 2011-06-07 Rorze Corporation Shuttle type conveying device, microplate feeding and collecting device, pickup device for microplate, cassette for microplate, and shelf for containing microplate
AU2007253481B2 (en) 2006-05-18 2013-01-17 Novo Nordisk A/S An injection device with mode locking means
CN101453982B (zh) 2006-05-30 2011-05-04 精达制药公司 两件式内部通道渗透递送系统流动调节器
WO2008021133A2 (en) 2006-08-09 2008-02-21 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
US8728059B2 (en) * 2006-09-29 2014-05-20 Covidien Lp System and method for assuring validity of monitoring parameter in combination with a therapeutic device
JP5634068B2 (ja) 2007-02-05 2014-12-03 ノボ・ノルデイスク・エー/エス 注射ボタン
EP2125081B1 (en) 2007-03-23 2017-12-20 Novo Nordisk A/S An injection device comprising a locking nut
EP2157967B1 (en) 2007-04-23 2013-01-16 Intarcia Therapeutics, Inc Suspension formulations of insulinotropic peptides and uses thereof
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
CA2724949A1 (en) * 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
US20090259176A1 (en) * 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
NZ593928A (en) * 2008-12-30 2014-03-28 Nupathe Inc Electronic control of drug delivery system
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US9008765B2 (en) 2009-02-12 2015-04-14 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
CN102573489A (zh) * 2009-08-10 2012-07-11 纽帕特公司 用离子电渗疗法治疗恶心和偏头痛的方法
CN104323981B (zh) 2009-09-28 2019-03-12 精达制药公司 基本稳态药物递送的快速建立和/或终止
WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
WO2011046927A1 (en) * 2009-10-13 2011-04-21 Nupathe,Inc. Transdermal methods and systems for the delivery of rizatriptan
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
US8986279B2 (en) 2010-02-10 2015-03-24 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
CN106955415B (zh) * 2011-03-24 2019-06-18 因卡伯实验室有限责任公司 用于治疗剂的两阶段经皮离子电渗递送的系统及方法
US8428708B1 (en) * 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
CN103998077B (zh) 2011-12-29 2017-05-31 诺沃—诺迪斯克有限公司 具有向上拨动/向下拨动定量机构的基于扭力弹簧的卷紧自动注射器笔
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
WO2016196851A2 (en) 2015-06-03 2016-12-08 Intarcia Therapeutics, Inc. Implant placement and removal systems
MX2018014016A (es) 2016-05-16 2019-08-01 Intarcia Therapeutics Inc Polipéptidos selectivos del receptor de glucagón y métodos para utilizarlos.
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
US20230082544A1 (en) 2020-02-18 2023-03-16 Novo Nordisk A/S Pharmaceutical formulations

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US3677268A (en) * 1969-11-28 1972-07-18 Sherwood Medical Ind Inc Iontophoresis electrode
US3794910A (en) * 1971-07-26 1974-02-26 Sherwood Medical Ind Inc Iontophoresis and conductivity analysis circuit
DE2339648C3 (de) * 1973-08-04 1979-09-13 Trebbin, Peter, 8833 Eichstaett Anästhesiegerät zur Behandlung der Zähne
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4211222A (en) * 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
JPS5347192A (en) * 1976-10-13 1978-04-27 Matsushita Electric Ind Co Ltd Device for introducing fluorine ion to tooth
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4177817A (en) * 1978-02-01 1979-12-11 C. R. Bard, Inc. Dual terminal transcutaneous electrode
US4215696A (en) * 1978-03-20 1980-08-05 Graphic Controls Corporation Biomedical electrode with pressurized skin contact
US4209020A (en) * 1978-09-19 1980-06-24 Nielsen R Frederick Electrode assembly
US4301794A (en) * 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
AU546785B2 (en) * 1980-07-23 1985-09-19 Commonwealth Of Australia, The Open-loop controlled infusion of diabetics
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4450844A (en) * 1981-11-23 1984-05-29 Hill Top Research, Inc. Patch system for use on the skin
WO1984004045A1 (en) * 1983-04-15 1984-10-25 Jack Kenneth Ibbott Therapeutic method and appliance employing flat battery
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4731926A (en) * 1985-02-19 1988-03-22 Drug Delivery Systems Inc. Method of manufacturing disposable and/or replenishable transdermal drug applicators
US4883457A (en) * 1983-08-18 1989-11-28 Drug Delivery Systems Inc. Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4851229A (en) * 1983-12-01 1989-07-25 Alza Corporation Composition comprising a therapeutic agent and a modulating agent
EP0225871B1 (en) * 1985-06-10 1990-03-14 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4698062A (en) * 1985-10-30 1987-10-06 Alza Corporation Medical device for pulsatile transdermal delivery of biologically active agents
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
EP0313638A4 (en) * 1987-05-15 1989-06-14 Martin H Newman IONTOPHORESIS INOPHORESIS DRUG ADMINISTRATION SYSTEM.
US4865582A (en) * 1987-06-05 1989-09-12 Drug Delivery Systems Inc. Disposable transdermal drug applicators

Also Published As

Publication number Publication date
CA2079316A1 (en) 1991-10-01
CA2079316C (en) 2002-01-01
JPH05505964A (ja) 1993-09-02
NO923769L (no) 1992-11-30
AU7991591A (en) 1991-10-30
KR0169084B1 (ko) 1999-01-15
JP3181289B2 (ja) 2001-07-03
WO1991015258A1 (en) 1991-10-17
DE69105202T2 (de) 1995-03-23
KR930700181A (ko) 1993-03-13
AU638581B2 (en) 1993-07-01
US5207752A (en) 1993-05-04
EP0522092B1 (en) 1994-11-17
FI924352A0 (fi) 1992-09-28
FI110066B (fi) 2002-11-29
DK0522092T3 (da) 1995-03-13
DE69105202D1 (de) 1994-12-22
GR3015116T3 (en) 1995-05-31
ES2067939T3 (es) 1995-04-01
ATE114118T1 (de) 1994-12-15
EP0522092A1 (en) 1993-01-13
NO308025B1 (no) 2000-07-10
NO923769D0 (no) 1992-09-28

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