FI924035A - Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel - Google Patents

Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel Download PDF

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Publication number
FI924035A
FI924035A FI924035A FI924035A FI924035A FI 924035 A FI924035 A FI 924035A FI 924035 A FI924035 A FI 924035A FI 924035 A FI924035 A FI 924035A FI 924035 A FI924035 A FI 924035A
Authority
FI
Finland
Prior art keywords
hydroxyhexansyraderives
saosom
medel
nya
therapeutic
Prior art date
Application number
FI924035A
Other languages
English (en)
Finnish (fi)
Other versions
FI924035A0 (fi
Inventor
Marc Lang
Guido Bold
Alexander Faessler
Peter Schneider
Hoogevest Peter Van
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI924035A0 publication Critical patent/FI924035A0/fi
Publication of FI924035A publication Critical patent/FI924035A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI924035A 1991-09-12 1992-09-09 Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel FI924035A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH268991 1991-09-12
CH98092 1992-03-27
CH200792 1992-06-25

Publications (2)

Publication Number Publication Date
FI924035A0 FI924035A0 (fi) 1992-09-09
FI924035A true FI924035A (fi) 1993-03-13

Family

ID=27172572

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924035A FI924035A (fi) 1991-09-12 1992-09-09 Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel

Country Status (15)

Country Link
EP (1) EP0532466A3 (fr)
JP (1) JPH05230095A (fr)
KR (1) KR930006050A (fr)
AU (1) AU661018B2 (fr)
CA (1) CA2077948A1 (fr)
CZ (1) CZ280292A3 (fr)
FI (1) FI924035A (fr)
HU (1) HUT63632A (fr)
IL (1) IL103126A (fr)
MX (1) MX9205208A (fr)
NO (1) NO923533L (fr)
NZ (1) NZ244288A (fr)
PL (1) PL169969B1 (fr)
RU (1) RU2067585C1 (fr)
SK (1) SK280292A3 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
EP0633881B1 (fr) * 1992-03-11 2003-10-29 Narhex Limited Derives amines d'hydrocarbures a substitution oxo et hydroxy
TW217410B (fr) * 1992-04-01 1993-12-11 Ciba Geigy
ES2093394T3 (es) 1992-12-23 1996-12-16 Ciba Geigy Ag Derivados de hidrazina antiretrovirales.
EP0618222A3 (en) * 1993-03-11 1997-01-02 Ciba Geigy Ag Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid.
EP0626178A1 (fr) * 1993-05-17 1994-11-30 Ciba-Geigy Ag Utilisation d'inhibiteurs de la protease du VIH dans le traitement des maladies tumorales
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) * 1993-10-01 1996-09-24 Abbott Laboratories Pharmaceutical composition
IL111991A (en) * 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
AU4117396A (en) * 1994-11-29 1996-06-19 Novartis Ag Morpholinoethylamide derivatives
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
AU7475396A (en) * 1995-10-30 1997-05-22 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US6232333B1 (en) 1996-11-21 2001-05-15 Abbott Laboratories Pharmaceutical composition
PL349354A1 (en) * 1999-01-28 2002-07-15 Chugai Pharmaceutical Co Ltd Substituted phenethylamine derivatives
US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
KR100708221B1 (ko) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
PT1248600E (pt) 2000-01-19 2008-08-25 Abbott Lab Formulações farmacêuticas melhoradas de inibidores da protease do vih
US6506786B2 (en) * 2001-02-13 2003-01-14 Pharmacor Inc. HIV protease inhibitors based on amino acid derivatives
CA2504344A1 (fr) * 2002-11-01 2004-05-21 Viropharma Incorporated Composes de benzofurane, compositions et methodes utilisees pour le traitement et la prophylaxie des infections virales induites par l'hepatite c et des maladies associees
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
AU2006319716B2 (en) 2005-11-30 2012-02-02 Taimed Biologics, Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
EP2044028B1 (fr) 2006-01-27 2012-05-16 Fibrogen, Inc. Cyanoisoquinolines en tant que stabilisateurs du facteur induit par l' hypoxie
RU2461557C2 (ru) 2006-04-04 2012-09-20 Файброджен, Инк. Соединения пирроло- и тиазолопиридина (варианты) и фармацевтическая композиция на их основе
JP5401652B2 (ja) 2006-09-21 2014-01-29 タイメッド バイオロジクス インコーポレイテッド プロテアーゼ阻害剤
NZ592741A (en) 2008-11-14 2013-03-28 Fibrogen Inc Thiochromene derivatives as hif hydroxylase inhibitors
TWI685487B (zh) 2013-01-24 2020-02-21 美商費比羅根公司 ｛［１-氰基-５-（４-氯苯氧基）-４-羥基-異喹啉-３-羰基］-胺基｝-乙酸之晶形

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126326A (en) * 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives

Also Published As

Publication number Publication date
NO923533L (no) 1993-03-15
PL169969B1 (pl) 1996-09-30
EP0532466A3 (en) 1993-06-16
CA2077948A1 (fr) 1993-03-13
SK280292A3 (en) 1995-02-08
FI924035A0 (fi) 1992-09-09
IL103126A0 (en) 1993-02-21
HUT63632A (en) 1993-09-28
PL295905A1 (en) 1993-05-17
KR930006050A (ko) 1993-04-20
JPH05230095A (ja) 1993-09-07
AU2288992A (en) 1993-03-18
EP0532466A2 (fr) 1993-03-17
CZ280292A3 (en) 1994-01-19
IL103126A (en) 1997-09-30
NZ244288A (en) 1995-03-28
NO923533D0 (no) 1992-09-11
RU2067585C1 (ru) 1996-10-10
AU661018B2 (en) 1995-07-13
HU9202925D0 (en) 1992-11-30
MX9205208A (es) 1993-03-01

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: NOVARTIS AG

FD Application lapsed