FI924035A0 - Nya 5-amino-4 -hydroxihexansyraderivat saosom terapeutiska medel. - Google Patents

Nya 5-amino-4 -hydroxihexansyraderivat saosom terapeutiska medel.

Info

Publication number
FI924035A0
FI924035A0 FI924035A FI924035A FI924035A0 FI 924035 A0 FI924035 A0 FI 924035A0 FI 924035 A FI924035 A FI 924035A FI 924035 A FI924035 A FI 924035A FI 924035 A0 FI924035 A0 FI 924035A0
Authority
FI
Finland
Prior art keywords
hydroxyhexansyraderives
saosom
medel
nya
therapeutic
Prior art date
Application number
FI924035A
Other languages
English (en)
Other versions
FI924035A (fi
Inventor
Marc Lang
Guido Bold
Alexander Faessler
Peter Schneider
Hoogevest Peter Van
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI924035A0 publication Critical patent/FI924035A0/fi
Publication of FI924035A publication Critical patent/FI924035A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI924035A 1991-09-12 1992-09-09 Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel FI924035A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH268991 1991-09-12
CH98092 1992-03-27
CH200792 1992-06-25

Publications (2)

Publication Number Publication Date
FI924035A0 true FI924035A0 (fi) 1992-09-09
FI924035A FI924035A (fi) 1993-03-13

Family

ID=27172572

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924035A FI924035A (fi) 1991-09-12 1992-09-09 Nya 5-amino-4-hydroxihexansyraderivat saosom terapeutiska medel

Country Status (15)

Country Link
EP (1) EP0532466A3 (fi)
JP (1) JPH05230095A (fi)
KR (1) KR930006050A (fi)
AU (1) AU661018B2 (fi)
CA (1) CA2077948A1 (fi)
CZ (1) CZ280292A3 (fi)
FI (1) FI924035A (fi)
HU (1) HUT63632A (fi)
IL (1) IL103126A (fi)
MX (1) MX9205208A (fi)
NO (1) NO923533L (fi)
NZ (1) NZ244288A (fi)
PL (1) PL169969B1 (fi)
RU (1) RU2067585C1 (fi)
SK (1) SK280292A3 (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
EP0633881B1 (en) * 1992-03-11 2003-10-29 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
TW217410B (fi) * 1992-04-01 1993-12-11 Ciba Geigy
ATE143004T1 (de) 1992-12-23 1996-10-15 Ciba Geigy Ag Antiretrovirale hydrazinderivate
EP0618222A3 (en) * 1993-03-11 1997-01-02 Ciba Geigy Ag Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid.
EP0626178A1 (de) * 1993-05-17 1994-11-30 Ciba-Geigy Ag Verwendung von Hemmstoffen von HIV-Aspartatproteasen zur Bekämpfung von Tumorerkrankungen
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en) * 1993-10-01 1996-09-24 Abbott Laboratories Pharmaceutical composition
IL111991A (en) * 1994-01-28 2000-07-26 Abbott Lab Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
WO1996016980A1 (en) * 1994-11-29 1996-06-06 Novartis Ag Morpholinoethylamide derivatives
US6037157A (en) 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
WO1997016188A1 (en) * 1995-10-30 1997-05-09 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US6232333B1 (en) 1996-11-21 2001-05-15 Abbott Laboratories Pharmaceutical composition
CN1343219A (zh) * 1999-01-28 2002-04-03 中外制药株式会社 取代的苯乙基胺衍生物
US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
KR100708221B1 (ko) 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
JP4769400B2 (ja) 2000-01-19 2011-09-07 アボット・ラボラトリーズ 改良された医薬配合物
US6506786B2 (en) 2001-02-13 2003-01-14 Pharmacor Inc. HIV protease inhibitors based on amino acid derivatives
AU2003290584B2 (en) * 2002-11-01 2009-07-16 Viropharma Incorporated Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases
US7388008B2 (en) 2004-08-02 2008-06-17 Ambrilia Biopharma Inc. Lysine based compounds
WO2007062526A1 (en) 2005-11-30 2007-06-07 Ambrilia Biopharma Inc. Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation
CA2640435C (en) 2006-01-27 2011-11-01 Fibrogen, Inc. Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif)
WO2007115315A2 (en) 2006-04-04 2007-10-11 Fibrogen, Inc. Pyrrolo- and thiazolo-pyridine compounds as hif modulators
CN102083793A (zh) 2006-09-21 2011-06-01 安布林生物制药公司 蛋白酶抑制剂
JP5649584B2 (ja) 2008-11-14 2015-01-07 フィブロジェン インコーポレイテッド Ｈｉｆヒドロキシラーゼ阻害剤としてのチオクロメン誘導体
AU2014209319B2 (en) 2013-01-24 2018-04-19 Fibrogen, Inc. Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126326A (en) * 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives

Also Published As

Publication number Publication date
PL295905A1 (en) 1993-05-17
EP0532466A2 (de) 1993-03-17
FI924035A (fi) 1993-03-13
AU661018B2 (en) 1995-07-13
NO923533L (no) 1993-03-15
IL103126A0 (en) 1993-02-21
AU2288992A (en) 1993-03-18
RU2067585C1 (ru) 1996-10-10
KR930006050A (ko) 1993-04-20
JPH05230095A (ja) 1993-09-07
HU9202925D0 (en) 1992-11-30
CA2077948A1 (en) 1993-03-13
EP0532466A3 (en) 1993-06-16
NO923533D0 (no) 1992-09-11
SK280292A3 (en) 1995-02-08
HUT63632A (en) 1993-09-28
NZ244288A (en) 1995-03-28
PL169969B1 (pl) 1996-09-30
IL103126A (en) 1997-09-30
MX9205208A (es) 1993-03-01
CZ280292A3 (en) 1994-01-19

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Legal Events

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GB Transfer or assigment of application

Owner name: NOVARTIS AG

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