FI921222A0 - Aminoguanidiner. - Google Patents
Aminoguanidiner.Info
- Publication number
- FI921222A0 FI921222A0 FI921222A FI921222A FI921222A0 FI 921222 A0 FI921222 A0 FI 921222A0 FI 921222 A FI921222 A FI 921222A FI 921222 A FI921222 A FI 921222A FI 921222 A0 FI921222 A0 FI 921222A0
- Authority
- FI
- Finland
- Prior art keywords
- optionally substituted
- heterocyclic radical
- alkyl
- aza
- carbamoyl
- Prior art date
Links
- -1 hydroxy, nitro, amino Chemical group 0.000 abstract 5
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Chemical class CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Chemical class C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- SMZMHUCIDGHERP-UHFFFAOYSA-N thieno[2,3-b]pyridine Chemical compound C1=CN=C2SC=CC2=C1 SMZMHUCIDGHERP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid Fuels And Fuel-Associated Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI971545A FI971545A (fi) | 1991-03-22 | 1997-04-11 | Aminoguanidineja |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9106179 | 1991-03-22 | ||
GB919106179A GB9106179D0 (en) | 1991-03-22 | 1991-03-22 | Improvements in or relating to organic compounds |
GB919107927A GB9107927D0 (en) | 1991-04-15 | 1991-04-15 | Improvements in or relating to organic compounds |
GB9107927 | 1991-04-15 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI921222A0 true FI921222A0 (fi) | 1992-03-20 |
FI921222A FI921222A (fi) | 1992-09-23 |
FI102371B1 FI102371B1 (fi) | 1998-11-30 |
FI102371B FI102371B (fi) | 1998-11-30 |
Family
ID=26298625
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI921222A FI102371B (fi) | 1991-03-22 | 1992-03-20 | Menetelmä indol-3-yyli-amino-guanidiiniyhdisteiden valmistamiseksi |
FI20010060A FI20010060A (fi) | 1991-03-22 | 2001-01-11 | 5-metoksi-indoli-3-karboksialdehydiamino-(pentyyliamino)metyleeni-hydratsoni |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI20010060A FI20010060A (fi) | 1991-03-22 | 2001-01-11 | 5-metoksi-indoli-3-karboksialdehydiamino-(pentyyliamino)metyleeni-hydratsoni |
Country Status (23)
Country | Link |
---|---|
US (1) | US5510353A (fi) |
EP (1) | EP0505322B1 (fi) |
JP (1) | JP2593022B2 (fi) |
KR (1) | KR100198018B1 (fi) |
AT (1) | ATE170838T1 (fi) |
AU (1) | AU651442B2 (fi) |
CA (1) | CA2063671C (fi) |
CZ (1) | CZ284339B6 (fi) |
DE (1) | DE69226894T2 (fi) |
DK (1) | DK0505322T3 (fi) |
ES (1) | ES2121836T3 (fi) |
FI (2) | FI102371B (fi) |
HK (1) | HK1011028A1 (fi) |
HU (2) | HUT64023A (fi) |
IE (1) | IE920895A1 (fi) |
IL (1) | IL101312A (fi) |
MX (1) | MX9201244A (fi) |
MY (1) | MY108158A (fi) |
NO (1) | NO179171C (fi) |
NZ (1) | NZ242069A (fi) |
RO (1) | RO109194B1 (fi) |
SG (1) | SG43221A1 (fi) |
SK (1) | SK279214B6 (fi) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0641198A1 (en) * | 1992-05-23 | 1995-03-08 | Smithkline Beecham Plc | Medicaments for the treatment of anxiety |
WO1994000113A2 (en) * | 1992-06-27 | 1994-01-06 | Smithkline Beecham Plc | Medicaments containing 5-ht4 receptor antagonists |
GB9226532D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
GB9226537D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
JP3035818B2 (ja) * | 1997-10-21 | 2000-04-24 | 日本精工株式会社 | 玉軸受 |
KR100364086B1 (ko) | 1998-04-16 | 2002-12-11 | 도시바 라이텍쿠 가부시키가이샤 | 고압 방전등 및 조명 장치 |
DK1104289T3 (da) * | 1998-08-21 | 2006-05-15 | Novartis Ag | Hidtil ukendte orale formuleringer for 5-HT4-agonister eller -antagonister |
TWI263496B (en) | 1999-12-10 | 2006-10-11 | Novartis Ag | Pharmaceutical combinations and their use in treating gastrointestinal disorders |
US20040092511A1 (en) * | 1999-12-10 | 2004-05-13 | Billstein Stephan Anthony | Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders |
GB0019357D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
GB0019359D0 (en) * | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel guanidines |
PT1424330E (pt) | 2001-08-10 | 2011-12-22 | Nippon Chemiphar Co | Activador do receptor ä responsivo a proliferadores peroxissomais |
IL161351A0 (en) | 2001-10-12 | 2004-09-27 | Nippon Chemiphar Co | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR delta |
AU2003209114A1 (en) * | 2002-02-14 | 2003-09-04 | Wyeth | Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
US6951881B2 (en) | 2002-05-10 | 2005-10-04 | Wyeth | (1-substituted-indol-3-yl) alkylidenehydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
US6906095B2 (en) | 2002-05-10 | 2005-06-14 | Wyeth | Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands |
ES2350123T3 (es) | 2003-01-28 | 2011-01-18 | Ironwood Pharmaceuticals, Inc. | Composiciones para el tratamiento de trastornos gastrointestinales. |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
AR045081A1 (es) * | 2003-07-24 | 2005-10-12 | Novartis Ag | Modificaciones estables de maleato de hidrogeno de tegaserod |
WO2005058819A2 (en) * | 2003-12-16 | 2005-06-30 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of tegaserod base and salts thereof |
WO2005105740A2 (en) * | 2004-04-26 | 2005-11-10 | Teva Pharmaceutical Industries Ltd. | Preparation of tegaserod and tegaserod maleate |
WO2006002212A1 (en) * | 2004-06-23 | 2006-01-05 | Dr. Reddy's Laboratories Ltd. | Tegaserod hemimaleate |
CA2582090A1 (en) * | 2004-10-19 | 2006-04-27 | Teva Pharmaceutical Industries Ltd. | Purification of tegaserod maleate |
CA2593854A1 (en) * | 2005-01-31 | 2006-08-10 | Novartis Ag | Organic compounds |
WO2006116953A1 (en) * | 2005-05-02 | 2006-11-09 | Zentiva, A.S. | A method for the preparation of tegaserod and slected salts thereof |
CZ298399B6 (cs) * | 2005-05-02 | 2007-09-19 | Zentiva, A. S. | Zpusob prípravy 2-[(5-methoxy-1 H-indol-3-yl) methylen]-N-pentylkarbazimidamidu (tegaserodu) |
TW200734321A (en) * | 2005-10-27 | 2007-09-16 | Teijin Pharma Ltd | Benzo [b] thiophen derivatives and a process for producing benzo [b] thiophen derivatives |
GB0524668D0 (en) * | 2005-12-02 | 2006-01-11 | Novartis Ag | Organic compounds |
GB0601953D0 (en) * | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
RU2435764C2 (ru) | 2006-04-18 | 2011-12-10 | Ниппон Кемифар Ко., Лтд. | АГЕНТ, АКТИВИРУЮЩИЙ РЕЦЕПТОР, АКТИВИРУЕМЫЙ ПРОЛИФЕРАТОРАМИ ПЕРОКСИСОМ δ |
CN100412059C (zh) * | 2006-06-06 | 2008-08-20 | 江苏奥赛康药业有限公司 | 一种替加色罗的制备方法 |
US20090306170A1 (en) * | 2006-11-09 | 2009-12-10 | Generics Uk Limited | Synthesis of tegaserod or a salt thereof |
EP1939176A1 (en) * | 2006-12-22 | 2008-07-02 | Novartis AG | Salts of Tegaserod |
ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
WO2008149138A1 (en) * | 2007-06-04 | 2008-12-11 | Generics [Uk] Limited | Tegaserod malate and polymorphic forms |
WO2008149139A2 (en) * | 2007-06-04 | 2008-12-11 | Generics [Uk] Limited | Tegaserod fumarate and polymorphic forms |
WO2008149140A2 (en) * | 2007-06-04 | 2008-12-11 | Generics [Uk] Limited | Tegaserod oxalate and polymorphic forms |
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WO2008149137A2 (en) * | 2007-06-04 | 2008-12-11 | Generics [Uk] Limited | Tegazerod benzoate and polymorphic forms |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
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WO2009053732A1 (en) | 2007-10-24 | 2009-04-30 | Generics [Uk] Limited | Novel salt |
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NZ588612A (en) | 2008-04-15 | 2012-08-31 | Nippon Chemiphar Co | Benzothiophen derivatives as activators of peroxisome proliferator activated receptor (PPAR) |
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CN102215834A (zh) * | 2008-09-19 | 2011-10-12 | 塞托凯恩药物科学公司 | 用于治疗术后肠炎症的脒腙 |
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CN103459382B (zh) | 2011-03-02 | 2016-06-29 | 拜奥埃内杰尼克斯公司 | 用于抑制pask的杂环化合物 |
US9908853B2 (en) | 2012-08-01 | 2018-03-06 | The Hospital For Sick Children | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof |
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WO2014052619A1 (en) | 2012-09-27 | 2014-04-03 | Irm Llc | Piperidine derivatives and compositions as modulators of gpr119 activity |
EP2724723A1 (en) | 2012-10-25 | 2014-04-30 | Universitätsklinikum Hamburg-Eppendorf | Tegaserod for use in the treatment of nerve injuries |
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GB842322A (en) * | 1956-10-01 | 1960-07-27 | Ici Ltd | Aminoguanidine derivatives |
GB842324A (en) * | 1956-10-01 | 1960-07-27 | Ici Ltd | Aminoguanidine derivatives |
GB842325A (en) * | 1956-10-01 | 1960-07-27 | Ici Ltd | Pharmaceutical compositions containing aminoguanidine derivatives |
GB842323A (en) * | 1956-10-01 | 1960-07-27 | Ici Ltd | Aminoguanidine derivatives |
US2855398A (en) * | 1956-11-19 | 1958-10-07 | Searle & Co | Amidines of the indole series |
US3317560A (en) * | 1963-01-03 | 1967-05-02 | Philips Corp | Indol-3-yl alkylguanidine derivatives |
DE3360148D1 (en) * | 1982-02-10 | 1985-06-05 | Beecham Group Plc | Guanidine derivatives |
US5095031A (en) * | 1990-08-20 | 1992-03-10 | Abbott Laboratories | Indole derivatives which inhibit leukotriene biosynthesis |
FR2669927B1 (fr) * | 1990-11-29 | 1994-04-08 | Adir Cie | Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
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1992
- 1992-03-06 HU HU9200761A patent/HUT64023A/hu unknown
- 1992-03-17 DK DK92810191T patent/DK0505322T3/da active
- 1992-03-17 AT AT92810191T patent/ATE170838T1/de active
- 1992-03-17 EP EP92810191A patent/EP0505322B1/en not_active Expired - Lifetime
- 1992-03-17 SG SG1996005765A patent/SG43221A1/en unknown
- 1992-03-17 DE DE69226894T patent/DE69226894T2/de not_active Expired - Lifetime
- 1992-03-17 ES ES92810191T patent/ES2121836T3/es not_active Expired - Lifetime
- 1992-03-18 MY MYPI92000449A patent/MY108158A/en unknown
- 1992-03-20 SK SK858-92A patent/SK279214B6/sk not_active IP Right Cessation
- 1992-03-20 AU AU13092/92A patent/AU651442B2/en not_active Expired
- 1992-03-20 CZ CS92858A patent/CZ284339B6/cs not_active IP Right Cessation
- 1992-03-20 NO NO921104A patent/NO179171C/no not_active IP Right Cessation
- 1992-03-20 CA CA002063671A patent/CA2063671C/en not_active Expired - Lifetime
- 1992-03-20 IE IE089592A patent/IE920895A1/en not_active IP Right Cessation
- 1992-03-20 MX MX9201244A patent/MX9201244A/es unknown
- 1992-03-20 IL IL101312A patent/IL101312A/xx active Protection Beyond IP Right Term
- 1992-03-20 NZ NZ242069A patent/NZ242069A/en not_active IP Right Cessation
- 1992-03-20 RO RO92-200369A patent/RO109194B1/ro unknown
- 1992-03-20 FI FI921222A patent/FI102371B/fi not_active IP Right Cessation
- 1992-03-21 KR KR1019920004680A patent/KR100198018B1/ko not_active IP Right Cessation
- 1992-03-21 JP JP4064281A patent/JP2593022B2/ja not_active Expired - Lifetime
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1995
- 1995-01-09 US US08/370,038 patent/US5510353A/en not_active Expired - Lifetime
- 1995-06-21 HU HU95P/P00315P patent/HU211510A9/hu unknown
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1998
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2001
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MA | Patent expired |