FI912964A7 - 2-tetrahydrofuraanin johdannaisten enantiomeerit, niiden välituotteet ja niiden valmistus - Google Patents

2-tetrahydrofuraanin johdannaisten enantiomeerit, niiden välituotteet ja niiden valmistus Download PDF

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Publication number
FI912964A7
FI912964A7 FI912964A FI912964A FI912964A7 FI 912964 A7 FI912964 A7 FI 912964A7 FI 912964 A FI912964 A FI 912964A FI 912964 A FI912964 A FI 912964A FI 912964 A7 FI912964 A7 FI 912964A7
Authority
FI
Finland
Prior art keywords
enantiomers
intermediates
preparation
tetrahydrofuran derivatives
tetrahydrofuran
Prior art date
Application number
FI912964A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI912964A0 (fi
FI912964L (fi
Inventor
Heinrich Estermann
William Joseph Houlihan
Russell Lee Underwood
Prasad Koteswara Kapa
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of FI912964A0 publication Critical patent/FI912964A0/fi
Publication of FI912964L publication Critical patent/FI912964L/fi
Publication of FI912964A7 publication Critical patent/FI912964A7/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574Esters of oxyacids of phosphorus
    • C07F9/65742Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
FI912964A 1990-06-19 1991-06-18 2-tetrahydrofuraanin johdannaisten enantiomeerit, niiden välituotteet ja niiden valmistus FI912964A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54043890A 1990-06-19 1990-06-19
US64739691A 1991-01-29 1991-01-29

Publications (3)

Publication Number Publication Date
FI912964A0 FI912964A0 (fi) 1991-06-18
FI912964L FI912964L (fi) 1991-12-20
FI912964A7 true FI912964A7 (fi) 1991-12-20

Family

ID=27066435

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912964A FI912964A7 (fi) 1990-06-19 1991-06-18 2-tetrahydrofuraanin johdannaisten enantiomeerit, niiden välituotteet ja niiden valmistus

Country Status (21)

Country Link
EP (1) EP0462935B1 (OSRAM)
JP (1) JP2709330B2 (OSRAM)
KR (1) KR920000772A (OSRAM)
AT (1) ATE125261T1 (OSRAM)
AU (2) AU649681B2 (OSRAM)
CA (1) CA2044786A1 (OSRAM)
CS (1) CS185191A3 (OSRAM)
DE (1) DE69111311T2 (OSRAM)
DK (1) DK0462935T3 (OSRAM)
ES (1) ES2076502T3 (OSRAM)
FI (1) FI912964A7 (OSRAM)
GR (1) GR3017437T3 (OSRAM)
HK (1) HK111996A (OSRAM)
HU (1) HU210548B (OSRAM)
IE (1) IE68417B1 (OSRAM)
IL (1) IL98524A (OSRAM)
MY (1) MY107022A (OSRAM)
NZ (1) NZ238573A (OSRAM)
PL (1) PL164981B1 (OSRAM)
PT (1) PT97994B (OSRAM)
TW (1) TW255897B (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208352A (en) * 1992-04-02 1993-05-04 Sandoz Ltd. Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds
ATE225982T1 (de) * 1998-07-17 2002-10-15 Fuji Photo Film Co Ltd Photozelle und photoelektrochemische zelle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0178261A3 (en) * 1984-10-10 1986-12-30 Sandoz Ag Substituted 2-furanyl or 5-oxo-2-furanyl-alkoxy phosphoryl alkyl cyclimmonium salts
US4601987A (en) * 1985-02-27 1986-07-22 Massachusetts Institute Of Technology Enzymatic production of optical isomers of 2-halopropionic acids
DE3666435D1 (en) * 1985-08-30 1989-11-23 Sandoz Ag Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals
US4673672A (en) 1985-10-28 1987-06-16 Sandoz Pharmaceuticals Corp. Substituted-[hydroxy(tetrahydro)-5-oxo-(2- and 3-furanyl or 2-thienyl)alkoxyphosphinyloxy]-alkanaminium hydroxide, inner salt oxides
US4868319A (en) * 1987-12-22 1989-09-19 Sandoz Pharm. Corp. Process for the preparation of monoalkylcarbamate group-containing compounds

Also Published As

Publication number Publication date
EP0462935B1 (en) 1995-07-19
HK111996A (en) 1996-07-05
NZ238573A (en) 1993-11-25
DK0462935T3 (da) 1995-11-06
CA2044786A1 (en) 1991-12-20
IL98524A (en) 1995-12-31
PT97994B (pt) 1998-11-30
ATE125261T1 (de) 1995-08-15
TW255897B (OSRAM) 1995-09-01
GR3017437T3 (en) 1995-12-31
IE68417B1 (en) 1996-06-12
HUT58340A (en) 1992-02-28
FI912964A0 (fi) 1991-06-18
MY107022A (en) 1995-08-30
AU649681B2 (en) 1994-06-02
HU911882D0 (en) 1991-12-30
PT97994A (pt) 1992-03-31
IL98524A0 (en) 1992-07-15
IE912081A1 (en) 1992-01-01
FI912964L (fi) 1991-12-20
PL290719A1 (en) 1992-07-27
JPH04270276A (ja) 1992-09-25
PL164981B1 (pl) 1994-10-31
ES2076502T3 (es) 1995-11-01
DE69111311D1 (de) 1995-08-24
AU677403B2 (en) 1997-04-24
AU7140794A (en) 1994-11-03
DE69111311T2 (de) 1996-03-14
EP0462935A1 (en) 1991-12-27
CS185191A3 (en) 1992-01-15
HU210548B (en) 1995-05-29
KR920000772A (ko) 1992-01-29
JP2709330B2 (ja) 1998-02-04
AU7843991A (en) 1992-01-02

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GB Transfer or assigment of application

Owner name: NOVARTIS AG

FD Application lapsed