FI895730A0 - Kloning och expression av apas transformerande vaextfaktor-b1 - Google Patents

Kloning och expression av apas transformerande vaextfaktor-b1

Info

Publication number
FI895730A0
FI895730A0 FI895730A FI895730A FI895730A0 FI 895730 A0 FI895730 A0 FI 895730A0 FI 895730 A FI895730 A FI 895730A FI 895730 A FI895730 A FI 895730A FI 895730 A0 FI895730 A0 FI 895730A0
Authority
FI
Finland
Prior art keywords
beta
tgf
cells
precursor
expression
Prior art date
Application number
FI895730A
Other languages
English (en)
Finnish (fi)
Inventor
Anthony F Purchio
Larry Gentry
Daniel Twardzik
Amy M Brunner
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of FI895730A0 publication Critical patent/FI895730A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Control Of Eletrric Generators (AREA)
  • Transmission And Conversion Of Sensor Element Output (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI895730A 1988-12-16 1989-11-29 Kloning och expression av apas transformerande vaextfaktor-b1 FI895730A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28591788A 1988-12-16 1988-12-16
US35017189A 1989-04-17 1989-04-17
US35372889A 1989-05-17 1989-05-17

Publications (1)

Publication Number Publication Date
FI895730A0 true FI895730A0 (fi) 1989-11-29

Family

ID=27403570

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895730A FI895730A0 (fi) 1988-12-16 1989-11-29 Kloning och expression av apas transformerande vaextfaktor-b1

Country Status (16)

Country Link
EP (1) EP0373994B1 (pt)
JP (1) JPH03130089A (pt)
KR (1) KR900009985A (pt)
CN (1) CN1044125A (pt)
AT (1) ATE118546T1 (pt)
AU (1) AU638952B2 (pt)
CA (1) CA2003886A1 (pt)
DE (1) DE68921167T2 (pt)
DK (1) DK638989A (pt)
ES (1) ES2070924T3 (pt)
FI (1) FI895730A0 (pt)
IE (1) IE67811B1 (pt)
IL (1) IL92489A0 (pt)
NO (1) NO179676C (pt)
NZ (1) NZ231581A (pt)
PT (1) PT92454B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626524B2 (en) * 1987-05-29 1992-08-06 Bristol-Myers Squibb Company Cloning and expression of simian transforming growth factor- beta 1
US5304541A (en) * 1988-12-15 1994-04-19 Bristol-Myers Squibb Company Methods using novel chimeric transforming growth factor-β1/β2
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7141392B2 (en) 2001-01-09 2006-11-28 Queen Mary And Westfield College Latent fusion protein
US6942853B2 (en) 2001-01-09 2005-09-13 Queen Mary And Westfield College Latent fusion protein
EP1279740A1 (en) * 2001-07-26 2003-01-29 Vrije Universiteit Brussel Recombinant vector derived from adeno-associated virus for gene therapy
US20110165623A1 (en) * 2004-01-06 2011-07-07 The Government Of The U.S. As Represented By The Secretary, Dept. Of Health & Human Services Compositions and Methods for the High Efficiency Expression of the Transforming Growth Factor-Beta Supergene Family
WO2012055541A1 (en) * 2010-10-25 2012-05-03 Bavarian Nordic A/S Tgf-beta in the development of conventional dendritic cells and uses thereof
CN104311631A (zh) * 2014-09-28 2015-01-28 苏州普罗达生物科技有限公司 转化生长因子β1激动剂多肽及其制备方法、应用
CN104211778A (zh) * 2014-09-28 2014-12-17 苏州普罗达生物科技有限公司 一种转化生长因子β1激动剂多肽及其制备方法、应用
RU2652312C2 (ru) * 2016-01-20 2018-04-25 Селл энд Джин Терапи Лтд Линейка биологически активных генно-терапевтических субстанций на основе гена tgfb1 для коррекции патологических состояний клеток органов и тканей и органов и тканей человека, способ получения и использования

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56026B1 (en) * 1982-10-19 1991-03-27 Cetus Corp Cysteine-depleted muteins of biologically active proteins
AU626524B2 (en) * 1987-05-29 1992-08-06 Bristol-Myers Squibb Company Cloning and expression of simian transforming growth factor- beta 1
CA2005120A1 (en) * 1988-12-15 1990-06-15 Anthony F. Purchio Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta
AU638705B2 (en) * 1989-04-20 1993-07-08 Lubrizol Corporation, The Methods for reducing friction between relatively slideable components using metal overbased colloidal disperse systems

Also Published As

Publication number Publication date
IL92489A0 (en) 1990-08-31
PT92454A (pt) 1990-06-29
AU4588289A (en) 1990-06-21
CA2003886A1 (en) 1990-06-16
JPH03130089A (ja) 1991-06-03
DK638989A (da) 1990-06-17
NO179676C (no) 1996-11-27
CN1044125A (zh) 1990-07-25
AU638952B2 (en) 1993-07-15
DK638989D0 (da) 1989-12-15
ES2070924T3 (es) 1995-06-16
NZ231581A (en) 1993-01-27
NO894759L (no) 1990-06-18
DE68921167T2 (de) 1995-06-01
EP0373994A1 (en) 1990-06-20
KR900009985A (ko) 1990-07-06
PT92454B (pt) 1995-07-18
IE67811B1 (en) 1996-05-01
IE893779L (en) 1990-06-16
NO179676B (no) 1996-08-19
ATE118546T1 (de) 1995-03-15
NO894759D0 (no) 1989-11-29
EP0373994B1 (en) 1995-02-15
DE68921167D1 (de) 1995-03-23

Similar Documents

Publication Publication Date Title
EP0293785A3 (en) Cloning and expression of simian transforming growth factor-ss1
FI895730A0 (fi) Kloning och expression av apas transformerande vaextfaktor-b1
US4835260A (en) Erythropoietin composition
ES2324046T5 (es) Procedimiento para controlar la sialilación de proteínas producidas por un cultivo de células de mamíferos
EP1489100A3 (en) Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
KR970703429A (ko) 동종 재조합에 영향을 주는 dna 구성물 및 이것의 사용 방법(dna construct for effecting homologous recombination and uses thereof)
ATE88501T1 (de) Rekombinante dns-expressionsvektoren.
ES2333724T3 (es) Secuencias lideres para uso en la produccion de proteinas.
Heartlein et al. Long-term production and delivery of human growth hormone in vivo.
JP2007300935A (ja) タンパク質を産生する能力を有し且つ無グルタミン培地中で成長する能力を有するグルタミン栄養要求性ヒト細胞
KR900009983A (ko) Tgf-베타1/베타2 : 새로운 망상 변형 성장인자-베타
CN102325881A (zh) 用于用动物细胞大量生产源自外源基因的蛋白质的表达载体及其应用
JPS6344897A (ja) ペプチド類の生産法
BR9905867A (pt) Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
Chung et al. Development of recombinant Chinese hamster ovary cell lines producing human thrombopoietin or its analog
EP0480923B1 (en) Method of producing proteins with fviii activity and/or fviii derivatives
US5610033A (en) Method of producing proteins with FVIII activity and/or FVIII derivatives
JP7531589B2 (ja) Ｃｈｏ細胞由来のタンパク質分泌因子及びそれを含む発現ベクター
Page Expression of foreign genes in mammalian cells
Shindo-Okada et al. Recognition of UAG termination codon by mammalian tyrosine tRNA containing 6-thioqueuine in the first position of the anticodon
ES2255177T3 (es) Fabricacion de proteinas mutadas humanas en celulas humanas por medio de la recombinacion homologa.
CA2295310A1 (en) Method for increasing secretion of proteins in eukaryotic host cells
Chen et al. Regulated secretion of prolactin by the mouse insulinoma cell line βTC-3
KR960034404A (ko) 조직형 플라스미노젠 액티베이터 단백질을 발현하는 형질전환된 동물 세포주
RU97117609A (ru) Экспрессия генов в клетках млекопитающих

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: ONCOGEN LIMITED PARTNERSHIP