PT92454A - Processo de clonacao e expressao de factor de crescimento transformante beta 1 de simio - Google Patents

Processo de clonacao e expressao de factor de crescimento transformante beta 1 de simio

Info

Publication number
PT92454A
PT92454A PT92454A PT9245489A PT92454A PT 92454 A PT92454 A PT 92454A PT 92454 A PT92454 A PT 92454A PT 9245489 A PT9245489 A PT 9245489A PT 92454 A PT92454 A PT 92454A
Authority
PT
Portugal
Prior art keywords
beta
tgf
cells
precursor
expression
Prior art date
Application number
PT92454A
Other languages
English (en)
Other versions
PT92454B (pt
Inventor
Daniel R Twardzik
Anthony F Purchio
Larry Gentry
Amy M Brunner
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of PT92454A publication Critical patent/PT92454A/pt
Publication of PT92454B publication Critical patent/PT92454B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Control Of Eletrric Generators (AREA)
  • Transmission And Conversion Of Sensor Element Output (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT92454A 1988-12-16 1989-11-29 Processo de clonacao e expressao de factor de crescimento transformante beta 1 de simio PT92454B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28591788A 1988-12-16 1988-12-16
US35017189A 1989-04-17 1989-04-17
US35372889A 1989-05-17 1989-05-17

Publications (2)

Publication Number Publication Date
PT92454A true PT92454A (pt) 1990-06-29
PT92454B PT92454B (pt) 1995-07-18

Family

ID=27403570

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92454A PT92454B (pt) 1988-12-16 1989-11-29 Processo de clonacao e expressao de factor de crescimento transformante beta 1 de simio

Country Status (16)

Country Link
EP (1) EP0373994B1 (pt)
JP (1) JPH03130089A (pt)
KR (1) KR900009985A (pt)
CN (1) CN1044125A (pt)
AT (1) ATE118546T1 (pt)
AU (1) AU638952B2 (pt)
CA (1) CA2003886A1 (pt)
DE (1) DE68921167T2 (pt)
DK (1) DK638989A (pt)
ES (1) ES2070924T3 (pt)
FI (1) FI895730A0 (pt)
IE (1) IE67811B1 (pt)
IL (1) IL92489A0 (pt)
NO (1) NO179676C (pt)
NZ (1) NZ231581A (pt)
PT (1) PT92454B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626524B2 (en) * 1987-05-29 1992-08-06 Bristol-Myers Squibb Company Cloning and expression of simian transforming growth factor- beta 1
US5304541A (en) * 1988-12-15 1994-04-19 Bristol-Myers Squibb Company Methods using novel chimeric transforming growth factor-β1/β2
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7141392B2 (en) 2001-01-09 2006-11-28 Queen Mary And Westfield College Latent fusion protein
US6942853B2 (en) 2001-01-09 2005-09-13 Queen Mary And Westfield College Latent fusion protein
EP1279740A1 (en) * 2001-07-26 2003-01-29 Vrije Universiteit Brussel Recombinant vector derived from adeno-associated virus for gene therapy
US20110165623A1 (en) * 2004-01-06 2011-07-07 The Government Of The U.S. As Represented By The Secretary, Dept. Of Health & Human Services Compositions and Methods for the High Efficiency Expression of the Transforming Growth Factor-Beta Supergene Family
WO2012055541A1 (en) * 2010-10-25 2012-05-03 Bavarian Nordic A/S Tgf-beta in the development of conventional dendritic cells and uses thereof
CN104311631A (zh) * 2014-09-28 2015-01-28 苏州普罗达生物科技有限公司 转化生长因子β1激动剂多肽及其制备方法、应用
CN104211778A (zh) * 2014-09-28 2014-12-17 苏州普罗达生物科技有限公司 一种转化生长因子β1激动剂多肽及其制备方法、应用
RU2652312C2 (ru) * 2016-01-20 2018-04-25 Селл энд Джин Терапи Лтд Линейка биологически активных генно-терапевтических субстанций на основе гена tgfb1 для коррекции патологических состояний клеток органов и тканей и органов и тканей человека, способ получения и использования

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56026B1 (en) * 1982-10-19 1991-03-27 Cetus Corp Cysteine-depleted muteins of biologically active proteins
AU626524B2 (en) * 1987-05-29 1992-08-06 Bristol-Myers Squibb Company Cloning and expression of simian transforming growth factor- beta 1
CA2005120A1 (en) * 1988-12-15 1990-06-15 Anthony F. Purchio Tgf-beta 1/beta 2: a novel chimeric transforming growth factor-beta
AU638705B2 (en) * 1989-04-20 1993-07-08 Lubrizol Corporation, The Methods for reducing friction between relatively slideable components using metal overbased colloidal disperse systems

Also Published As

Publication number Publication date
IL92489A0 (en) 1990-08-31
AU4588289A (en) 1990-06-21
CA2003886A1 (en) 1990-06-16
JPH03130089A (ja) 1991-06-03
DK638989A (da) 1990-06-17
NO179676C (no) 1996-11-27
CN1044125A (zh) 1990-07-25
FI895730A0 (fi) 1989-11-29
AU638952B2 (en) 1993-07-15
DK638989D0 (da) 1989-12-15
ES2070924T3 (es) 1995-06-16
NZ231581A (en) 1993-01-27
NO894759L (no) 1990-06-18
DE68921167T2 (de) 1995-06-01
EP0373994A1 (en) 1990-06-20
KR900009985A (ko) 1990-07-06
PT92454B (pt) 1995-07-18
IE67811B1 (en) 1996-05-01
IE893779L (en) 1990-06-16
NO179676B (no) 1996-08-19
ATE118546T1 (de) 1995-03-15
NO894759D0 (no) 1989-11-29
EP0373994B1 (en) 1995-02-15
DE68921167D1 (de) 1995-03-23

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990930