FI892454L - Nya bensimidazolderivat, foerfarande foer framstaellning av desamma och farmaceutisk komposition innehaollande desamma. - Google Patents

Nya bensimidazolderivat, foerfarande foer framstaellning av desamma och farmaceutisk komposition innehaollande desamma. Download PDF

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Publication number
FI892454L
FI892454L FI892454A FI892454A FI892454L FI 892454 L FI892454 L FI 892454L FI 892454 A FI892454 A FI 892454A FI 892454 A FI892454 A FI 892454A FI 892454 L FI892454 L FI 892454L
Authority
FI
Finland
Prior art keywords
desamma
bensimidazolderivat
farmaceutisk
komposition
nya
Prior art date
Application number
FI892454A
Other languages
English (en)
Finnish (fi)
Other versions
FI892454A0 (fi
FI892454A7 (fi
Inventor
Tomas Boerje Alminger
Rolf Axel Bergman
Gunnel Elisabeth Sunden
Hans Bundgaard
Per Lennart Lindberg
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of FI892454A0 publication Critical patent/FI892454A0/fi
Publication of FI892454A7 publication Critical patent/FI892454A7/fi
Publication of FI892454L publication Critical patent/FI892454L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI892454A 1986-11-21 1987-11-20 Nya bensimidazolderivat, foerfarande foer framstaellning av desamma och farmaceutisk komposition innehaollande desamma. FI892454L (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds
PCT/SE1987/000546 WO1988003921A1 (en) 1986-11-21 1987-11-20 New benzimidazole derivatives a process for production thereof and a pharmaceutical composition containing the same

Publications (3)

Publication Number Publication Date
FI892454A0 FI892454A0 (fi) 1989-05-19
FI892454A7 FI892454A7 (fi) 1989-05-19
FI892454L true FI892454L (fi) 1989-05-19

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
FI892454A FI892454L (fi) 1986-11-21 1987-11-20 Nya bensimidazolderivat, foerfarande foer framstaellning av desamma och farmaceutisk komposition innehaollande desamma.

Country Status (24)

Country Link
EP (3) EP0332647A1 (enExample)
JP (1) JPH02500744A (enExample)
KR (1) KR890700125A (enExample)
AT (1) ATE84032T1 (enExample)
AU (1) AU612129B2 (enExample)
DE (1) DE3783356T2 (enExample)
DK (1) DK365488A (enExample)
EG (1) EG18379A (enExample)
ES (1) ES2052603T3 (enExample)
FI (1) FI892454L (enExample)
GR (1) GR3007385T3 (enExample)
HU (1) HU204814B (enExample)
IE (2) IE940326L (enExample)
IL (1) IL84504A (enExample)
IS (1) IS1565B (enExample)
LV (1) LV10954B (enExample)
MY (1) MY101784A (enExample)
NO (1) NO173998C (enExample)
NZ (2) NZ234564A (enExample)
PL (1) PL157655B1 (enExample)
PT (1) PT86186B (enExample)
RU (1) RU2062778C1 (enExample)
WO (1) WO1988003921A1 (enExample)
YU (1) YU47116B (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
AU617217B2 (en) * 1988-09-20 1991-11-21 Hisamitsu Pharmaceutical Co., Inc. Novel dibenz(b,e)oxepin derivatives
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
DE69132082T2 (de) * 1990-10-17 2000-08-31 Takeda Chemical Industries, Ltd. Pyridin-Derivate, Verfahren zu deren Herstellung und Anwendung
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
JP2759228B2 (ja) * 1992-05-21 1998-05-28 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
EP0983263A1 (en) * 1997-05-30 2000-03-08 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
AU754965B2 (en) * 1997-12-31 2002-11-28 University Of Kansas, The Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
AU2277201A (en) * 1999-12-17 2001-06-25 Ariad Pharmaceuticals, Inc. Novel purines
AU2001294228A1 (en) * 2000-10-12 2002-04-22 Takeda Chemical Industries Ltd. Benzimidazole compounds, process for producing the same and use thereof
EP1437352A4 (en) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
KR100788778B1 (ko) * 2002-07-19 2007-12-27 윈스턴 파마슈티컬즈, 엘엘씨 벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
GB0400781D0 (en) * 2004-01-14 2004-02-18 Novartis Ag Organic compounds
WO2006021463A1 (en) * 2004-08-27 2006-03-02 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
CA2616512A1 (en) * 2005-07-28 2007-02-08 Intervet International B.V. Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
WO2016061190A1 (en) 2014-10-14 2016-04-21 The Board Of Trustees Of The Leland Stanford Junior University Method for treating neurodegenerative diseases
ES2830447T3 (es) 2015-12-15 2021-06-03 Univ Leland Stanford Junior Método para la prevención y/o el tratamiento del deterioro cognitivo asociado al envejecimiento y la neuroinflamación
BR112021002165A2 (pt) 2018-08-06 2021-05-04 The Board Of Trustees Of The Leland Stanford Junior University composto, composição farmacêutica, e, métodos para tratar uma doença neurodegenerativa e deficiência cognitiva associada ao envelhecimento e neuroinflamação
EP4019496B1 (en) * 2019-08-20 2024-06-05 ONO Pharmaceutical Co., Ltd. Salt and crystal form of compound having agonistic activity to s1p5 receptor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (enExample) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
RU2062778C1 (ru) 1996-06-27
WO1988003921A1 (en) 1988-06-02
FI892454A0 (fi) 1989-05-19
KR890700125A (ko) 1989-03-02
DK365488D0 (da) 1988-07-01
DK365488A (da) 1988-07-01
IE61178B1 (en) 1994-10-05
NZ234564A (en) 1991-04-26
LV10954A (lv) 1995-12-20
IS1565B (is) 1994-12-13
FI892454A7 (fi) 1989-05-19
LV10954B (en) 1996-08-20
EG18379A (en) 1992-11-30
GR3007385T3 (enExample) 1993-07-30
NO883229L (no) 1988-09-16
EP0279149A2 (en) 1988-08-24
IE940326L (en) 1988-05-21
PL157655B1 (pl) 1992-06-30
NZ222495A (en) 1991-04-26
ES2052603T3 (es) 1994-07-16
IE873125L (en) 1988-05-21
NO883229D0 (no) 1988-07-20
EP0510719A1 (en) 1992-10-28
HUT51269A (en) 1990-04-28
HU204814B (en) 1992-02-28
NO173998C (no) 1994-03-02
PT86186A (en) 1987-12-01
YU47116B (sh) 1994-12-28
AU612129B2 (en) 1991-07-04
EP0279149B1 (en) 1992-12-30
IL84504A (en) 1994-10-07
IS3284A7 (is) 1988-05-22
AU8330287A (en) 1988-06-16
EP0279149A3 (en) 1988-08-31
JPH02500744A (ja) 1990-03-15
ATE84032T1 (de) 1993-01-15
YU211087A (en) 1988-12-31
MY101784A (en) 1992-01-17
DE3783356D1 (de) 1993-02-11
EP0332647A1 (en) 1989-09-20
PL268927A1 (en) 1989-01-23
PT86186B (pt) 1990-08-31
DE3783356T2 (de) 1993-04-15
NO173998B (no) 1993-11-22

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: AKTIEBOLAGET HAESSLE