FI885543A - Dna-segment, polypeptider och anti-kroppar anslutande till human vaevnadsfaktor. - Google Patents

Dna-segment, polypeptider och anti-kroppar anslutande till human vaevnadsfaktor. Download PDF

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Publication number
FI885543A
FI885543A FI885543A FI885543A FI885543A FI 885543 A FI885543 A FI 885543A FI 885543 A FI885543 A FI 885543A FI 885543 A FI885543 A FI 885543A FI 885543 A FI885543 A FI 885543A
Authority
FI
Finland
Prior art keywords
vaevnadsfaktor
croppar
anslutande
polypeptider
oti
Prior art date
Application number
FI885543A
Other languages
English (en)
Other versions
FI100184B (fi
FI885543A0 (fi
Inventor
Thomas S Edgington
James H Morrissey
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27364291&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI885543(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/067,103 external-priority patent/US5110730A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of FI885543A publication Critical patent/FI885543A/fi
Publication of FI885543A0 publication Critical patent/FI885543A0/fi
Priority to FI954347A priority Critical patent/FI97813C/fi
Application granted granted Critical
Publication of FI100184B publication Critical patent/FI100184B/fi

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809Fused cells, e.g. hybridoma
FI885543A 1987-03-31 1988-11-29 Ihmisen kudostekijään liittyvä DNA-kappale ja yhdistelmä-DNA-molekyyli sekä menetelmä proteiinin valmistamiseksi FI100184B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI954347A FI97813C (fi) 1987-03-31 1995-09-15 Monoklonaaliset vasta-ainekoostumukset ja monoklonaalisia vasta-aineita tuottavat hybridomat

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US3304787A 1987-03-31 1987-03-31
US3304787 1987-03-31
US07/067,103 US5110730A (en) 1987-03-31 1987-06-25 Human tissue factor related DNA segments
US6710387 1987-06-25
US07/165,939 US5223427A (en) 1987-03-31 1988-03-09 Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain
US16593988 1988-03-09
US8800998 1988-03-29
PCT/US1988/000998 WO1988007543A1 (en) 1987-03-31 1988-03-29 Human tissue factor related dna segments, polypeptides and antibodies

Publications (3)

Publication Number Publication Date
FI885543A true FI885543A (fi) 1988-11-29
FI885543A0 FI885543A0 (fi) 1988-11-29
FI100184B FI100184B (fi) 1997-10-15

Family

ID=27364291

Family Applications (2)

Application Number Title Priority Date Filing Date
FI885543A FI100184B (fi) 1987-03-31 1988-11-29 Ihmisen kudostekijään liittyvä DNA-kappale ja yhdistelmä-DNA-molekyyli sekä menetelmä proteiinin valmistamiseksi
FI954347A FI97813C (fi) 1987-03-31 1995-09-15 Monoklonaaliset vasta-ainekoostumukset ja monoklonaalisia vasta-aineita tuottavat hybridomat

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI954347A FI97813C (fi) 1987-03-31 1995-09-15 Monoklonaaliset vasta-ainekoostumukset ja monoklonaalisia vasta-aineita tuottavat hybridomat

Country Status (13)

Country Link
US (2) US5223427A (fi)
EP (2) EP0309548B1 (fi)
JP (1) JP2809415B2 (fi)
AT (1) ATE246200T1 (fi)
AU (1) AU605864B2 (fi)
CA (1) CA1340544C (fi)
DE (1) DE3856560T2 (fi)
DK (1) DK175703B1 (fi)
ES (1) ES2009590A6 (fi)
FI (2) FI100184B (fi)
NO (1) NO305211B1 (fi)
PT (1) PT87138B (fi)
WO (1) WO1988007543A1 (fi)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7084251B1 (en) 1987-02-12 2006-08-01 Genentech, Inc. Methods and Deoxyribonucleic acid for the preparation of tissue factor protein
US6994988B1 (en) 1987-02-12 2006-02-07 Genetech, Inc. Methods and deoxyribonucleic acid for the preparation of tissue factor protein
US6001978A (en) * 1987-03-31 1999-12-14 The Scripps Research Institute Human tissue factor related DNA segments polypeptides and antibodies
IL87172A (en) * 1987-07-23 1994-12-29 Univ Washington A method of inhibiting the isolation of a purer tissue factor
NO892506L (no) * 1988-06-17 1989-12-18 Sinai School Medicine Kloning og ekspresjon av human vevsfaktor.
US5472850A (en) * 1991-04-10 1995-12-05 Oklahoma Medical Research Foundation Quantitative clotting assay for activated factor VII
US5298599A (en) * 1988-12-30 1994-03-29 Oklahoma Medical Research Foundation Expression and purification of recombinant soluble tissue factor
US6203816B1 (en) * 1990-11-13 2001-03-20 Corvas International, Inc. Tissue factor based prothrombin time reagent
US5314695A (en) 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
CA2077906A1 (en) * 1991-01-10 1992-07-11 Kimihiko Matsuzawa Method for measurement of tissue factor in high sensitivity and measurement kit therefor
US5374617A (en) * 1992-05-13 1994-12-20 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with FVIIa
US5504064A (en) * 1991-04-10 1996-04-02 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with an activator of FVII
US6004555A (en) * 1992-03-05 1999-12-21 Board Of Regents, The University Of Texas System Methods for the specific coagulation of vasculature
US6093399A (en) * 1992-03-05 2000-07-25 Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of vasculature
US5877289A (en) * 1992-03-05 1999-03-02 The Scripps Research Institute Tissue factor compositions and ligands for the specific coagulation of vasculature
US6036955A (en) * 1992-03-05 2000-03-14 The Scripps Research Institute Kits and methods for the specific coagulation of vasculature
US6749853B1 (en) * 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US20030171292A1 (en) * 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US5879677A (en) * 1992-12-09 1999-03-09 The Scripps Research Institute Method for inhibition of cerebral tissue factor mediated reperfusion damage
US20010048924A1 (en) * 1998-06-22 2001-12-06 Del Zoppo Gregory J. Method for inhibiting cerebral tissue factor mediated reperfusion damage
CA2180140A1 (en) * 1993-12-27 1995-07-06 Jeffrey I. Weitz Methods and compositions for inhibiting thrombogenesis
DK0833911T3 (da) * 1995-06-07 2004-08-30 Ortho Mcneil Pharm Inc CDR-transplanterede anti-vævsfaktorantistoffer og fremgangsmåder til anvendelse deraf
US5837684A (en) * 1995-06-07 1998-11-17 Nycomed Imaging As Peptides
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
ATE244579T1 (de) * 1997-01-22 2003-07-15 Univ Texas Verfahren und zusammensetzungen des gewebefaktors zur koagulation und behandlung von tumoren
US20030109680A1 (en) * 2001-11-21 2003-06-12 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
US20060235209A9 (en) * 1997-03-10 2006-10-19 Jin-An Jiao Use of anti-tissue factor antibodies for treating thromboses
US20040229282A1 (en) * 1997-03-10 2004-11-18 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
US5986065A (en) * 1997-03-10 1999-11-16 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
US7749498B2 (en) * 1997-03-10 2010-07-06 Genentech, Inc. Antibodies for inhibiting blood coagulation and methods of use thereof
WO1998048283A1 (en) * 1997-04-23 1998-10-29 Instrumentation Laboratory S.P.A. Recombinant rabbit tissue factor based prothrombin time reagent
ES2364266T3 (es) * 1998-04-03 2011-08-30 Chugai Seiyaku Kabushiki Kaisha Anticuerpo humanizado hacia el factor tisular humano (tf) y procedimiento para construir el anticuerpo humanizado.
BR9912053A (pt) 1998-07-13 2001-04-03 Univ Texas Processos de tratamento de câncer utilizando conjugados terapêuticos que se ligam a aminofosfolipìdios
US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
CA2335274A1 (en) 1998-07-15 2000-01-27 Genentech, Inc. Tissue factor protein variants with increased affinity for coagulation factor fvii/fviia
US7764130B2 (en) * 1999-01-22 2010-07-27 Multigig Inc. Electronic circuitry
EP2351483A1 (en) * 1999-10-01 2011-08-03 Chugai Seiyaku Kabushiki Kaisha Prevention and treatment of blood coagulation-related diseases
JP2003518075A (ja) 1999-12-24 2003-06-03 ジェネンテック・インコーポレーテッド 生理活性化合物の消失半減期延長のための方法及び組成物
US6703494B2 (en) * 2000-03-16 2004-03-09 Genentech, Inc. Anti-tissue factor antibodies with enhanced anticoagulant potency
US6855509B2 (en) * 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
US20030143225A1 (en) * 2001-03-08 2003-07-31 Genentech, Inc. Combinations of anti-tissue factor antibodies and anticoagulant and/or antiplatelet agents
US20030129193A1 (en) * 2001-09-27 2003-07-10 Board Of Regents, The University Of Texas System And Peregrine Pharmaceuticals, Inc. Combined methods for tumor vasculature coaguligand treatment
CN1575302A (zh) * 2001-10-02 2005-02-02 诺沃挪第克公司 人组织因子抗体
PL372138A1 (en) * 2001-10-15 2005-07-11 Chiron Corporation Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)
US7399743B2 (en) * 2001-10-26 2008-07-15 The Scripps Research Institute Targeted thrombosis
US20030190705A1 (en) * 2001-10-29 2003-10-09 Sunol Molecular Corporation Method of humanizing immune system molecules
US7357928B2 (en) 2002-04-08 2008-04-15 University Of Louisville Research Foundation, Inc. Method for the diagnosis and prognosis of malignant diseases
US7541150B2 (en) * 2002-04-08 2009-06-02 University Of Louisville Research Foundation, Inc Method for the diagnosis and prognosis of malignant diseases
JP4460443B2 (ja) * 2002-05-01 2010-05-12 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 抗凝固剤としての新規組織因子標的化された抗体
US7579000B2 (en) 2002-05-01 2009-08-25 Bayer Schering Pharma Ag Tissue factor targeted antibodies as anticoagulants
US20050106139A1 (en) * 2002-10-31 2005-05-19 Ivan Svendsen Humanized tissue factor antibodies
US20040198660A1 (en) * 2002-11-06 2004-10-07 Petersen Lars Christian Tissue factor antagonist and protein C polypeptide compositions
EP1587549A2 (en) * 2003-01-22 2005-10-26 Novo Nordisk A/S Radiolabelled tissue factor binding agent and the use thereof
US7425328B2 (en) * 2003-04-22 2008-09-16 Purdue Pharma L.P. Tissue factor antibodies and uses thereof
EP1633309A4 (en) * 2003-05-30 2007-06-13 Centocor Inc METHOD FOR INHIBITING TUMOR GROWTH WITH ANTI-TISSUE FACTOR ANTIBODIES
US7605235B2 (en) 2003-05-30 2009-10-20 Centocor, Inc. Anti-tissue factor antibodies and compositions
US9708410B2 (en) 2003-05-30 2017-07-18 Janssen Biotech, Inc. Anti-tissue factor antibodies and compositions
WO2005004793A2 (en) * 2003-06-19 2005-01-20 Tanox Inc. Compositions and methods for treating coagulation related disorders
EP1667718A4 (en) * 2003-08-29 2007-05-02 Centocor Inc METHOD FOR STIMULATING THE SURVIVAL OF A GRAFT WITH ANTI-TISSUE FACTOR ANTIBODY
RU2006136267A (ru) * 2004-03-17 2008-04-27 Чирон Корпорейшн (Us) Лечение тяжелой внебольничной пневмонии путем введения ингибитора пути тканевого фактора (tfpi)
WO2005118646A2 (en) * 2004-04-26 2005-12-15 Centocor, Inc. Epitope directed selection of antibodies to murine tissue factor
US7790405B2 (en) * 2004-04-26 2010-09-07 Centocor, Inc. Solution phase biopanning method using engineered decoy proteins
US7514539B2 (en) * 2004-04-26 2009-04-07 Centocor, Inc. Epitope directed selection of antibodies to murine tissue factor
JP5017097B2 (ja) * 2004-04-26 2012-09-05 セントカー・インコーポレーテツド 設計デコイタンパク質を用いる溶液相バイオパニング方法
EP1676574A3 (en) 2004-12-30 2006-07-26 Johnson & Johnson Vision Care, Inc. Methods for promoting survival of transplanted tissues and cells
NZ568762A (en) * 2005-11-07 2011-11-25 Scripps Research Inst Use of an inhibitor of tissue factor signaling in the manufacture of a medcament for inhibiting or suppressing tissue factor/tissue factor VIIa signaling involving protease activated receptor 2 in a mammal
UA109633C2 (uk) 2008-12-09 2015-09-25 Антитіло людини проти тканинного фактора
WO2011062997A2 (en) 2009-11-17 2011-05-26 Musc Foundation For Research Development Human monoclonal antibodies to human nucleolin
EP2380905A1 (en) 2010-04-19 2011-10-26 Thrombotargets Europe, S.L. Phospholipid-enriched vesicles bearing tissue factor having haemostatic activities and uses thereof
CN106084053B (zh) * 2010-06-15 2020-01-17 根马布股份公司 针对组织因子的人抗体药物缀合物
WO2012033518A1 (en) * 2010-09-09 2012-03-15 The Scripps Research Institute Methods and compositions for treating metabolic disorders
US8722044B2 (en) * 2011-03-15 2014-05-13 Janssen Biotech, Inc. Human tissue factor antibody and uses thereof
WO2012167173A1 (en) 2011-06-02 2012-12-06 The University Of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles
CN103566378B (zh) * 2013-09-09 2016-09-14 南京海智生物工程有限公司 基于组织因子的肿瘤核酸疫苗、制备方法及其应用
KR102372245B1 (ko) * 2013-11-21 2022-03-08 젠맵 에이/에스 항체-약물 접합체 동결건조 제제
EP3291839A1 (en) 2015-05-05 2018-03-14 The University of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
WO2018208856A1 (en) 2017-05-08 2018-11-15 Gritstone Oncology, Inc. Alphavirus neoantigen vectors
KR101989954B1 (ko) * 2017-10-16 2019-06-17 고려대학교 산학협력단 돼지 조직인자 세포외 도메인 단백질을 특이적으로 인식하는 단일클론항체 및 이의 용도
KR20200118029A (ko) * 2018-01-04 2020-10-14 아이코닉 테라퓨틱스, 인코포레이티드 항-조직 인자 항체, 항체-약물 결합체, 및 관련 방법
TW202110870A (zh) 2019-05-30 2021-03-16 美商葛利史東腫瘤科技公司 經修飾之腺病毒
CN116438308A (zh) 2020-08-06 2023-07-14 磨石生物公司 多表位疫苗盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548904A (en) * 1982-12-03 1985-10-22 Molecular Genetics Research & Development Protein sequencing method
IE81149B1 (en) * 1987-02-12 2000-05-03 Genentech Inc Methods and deoxyribonucleic acid for the preparation of tissue factor protein
JPH02501263A (ja) * 1987-06-12 1990-05-10 マウント サイナイ スクール オブ メディシン オブ ザ シティー ユニバーシティー オブ ニューヨーク ヒトの組織因子のクローニングと形質発現

Also Published As

Publication number Publication date
US5223427A (en) 1993-06-29
EP1364969A3 (en) 2004-12-29
NO885326L (no) 1989-01-30
FI97813C (fi) 1997-02-25
FI97813B (fi) 1996-11-15
EP0309548B1 (en) 2003-07-30
FI100184B (fi) 1997-10-15
JPH01503438A (ja) 1989-11-22
ES2009590A6 (es) 1989-10-01
AU1627488A (en) 1988-11-02
US5622931A (en) 1997-04-22
WO1988007543A1 (en) 1988-10-06
DE3856560D1 (de) 2003-09-04
JP2809415B2 (ja) 1998-10-08
NO305211B1 (no) 1999-04-19
EP0309548A4 (en) 1991-08-07
PT87138A (pt) 1988-04-01
FI954347A (fi) 1995-09-15
DE3856560T2 (de) 2004-08-05
PT87138B (pt) 1992-07-31
NO885326D0 (no) 1988-11-29
EP0309548A1 (en) 1989-04-05
AU605864B2 (en) 1991-01-24
EP1364969A2 (en) 2003-11-26
DK175703B1 (da) 2005-01-24
CA1340544C (en) 1999-05-18
ATE246200T1 (de) 2003-08-15
FI954347A0 (fi) 1995-09-15
DK666888A (da) 1989-01-31
FI885543A0 (fi) 1988-11-29
DK666888D0 (da) 1988-11-29

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