FI881651A - Terapeutiska nukleosider. - Google Patents

Terapeutiska nukleosider. Download PDF

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Publication number
FI881651A
FI881651A FI881651A FI881651A FI881651A FI 881651 A FI881651 A FI 881651A FI 881651 A FI881651 A FI 881651A FI 881651 A FI881651 A FI 881651A FI 881651 A FI881651 A FI 881651A
Authority
FI
Finland
Prior art keywords
nucleosider
therapeutic
therapeutic nucleosider
Prior art date
Application number
FI881651A
Other languages
English (en)
Other versions
FI881651A0 (fi
FI87214C (fi
FI87214B (fi
Inventor
George Walter Koszalka
Thomas Anthony Krenitsky
Janet Litster Rideout
Charlene Louise Burns
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878708512A external-priority patent/GB8708512D0/en
Priority claimed from GB878712691A external-priority patent/GB8712691D0/en
Priority claimed from GB878723013A external-priority patent/GB8723013D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI881651A0 publication Critical patent/FI881651A0/fi
Publication of FI881651A publication Critical patent/FI881651A/fi
Application granted granted Critical
Publication of FI87214B publication Critical patent/FI87214B/fi
Publication of FI87214C publication Critical patent/FI87214C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
FI881651A 1987-04-09 1988-04-08 Terapeutiska nukleosider FI87214C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8708512 1987-04-09
GB878708512A GB8708512D0 (en) 1987-04-09 1987-04-09 Therapeutic nucleosides
GB878712691A GB8712691D0 (en) 1987-05-29 1987-05-29 Therapeutic nucleosides
GB8712691 1987-05-29
GB8723013 1987-09-30
GB878723013A GB8723013D0 (en) 1987-09-30 1987-09-30 Therapeutic nucleosides

Publications (4)

Publication Number Publication Date
FI881651A0 FI881651A0 (fi) 1988-04-08
FI881651A true FI881651A (fi) 1988-10-10
FI87214B FI87214B (fi) 1992-08-31
FI87214C FI87214C (fi) 1992-12-10

Family

ID=27263377

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881651A FI87214C (fi) 1987-04-09 1988-04-08 Terapeutiska nukleosider

Country Status (20)

Country Link
US (1) US5068320A (fi)
EP (1) EP0286425B1 (fi)
JP (1) JP2763888B2 (fi)
KR (1) KR880012630A (fi)
AP (1) AP78A (fi)
AT (1) ATE116984T1 (fi)
AU (1) AU608590B2 (fi)
CA (1) CA1326237C (fi)
CS (1) CS274461B2 (fi)
DE (1) DE3852710T2 (fi)
DK (1) DK191688A (fi)
FI (1) FI87214C (fi)
HU (1) HU201954B (fi)
IL (1) IL86007A0 (fi)
MC (1) MC1915A1 (fi)
NO (1) NO171641C (fi)
NZ (1) NZ224189A (fi)
PL (1) PL154956B1 (fi)
PT (1) PT87191B (fi)
RU (1) RU1779256C (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
US5185437A (en) * 1987-04-09 1993-02-09 Burroughs Wellcome Co. Therapeutic nucleosides
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
JPH02164881A (ja) * 1988-10-24 1990-06-25 Wellcome Found Ltd:The 治療用ヌクレオシド化合物
AU4817490A (en) * 1988-11-29 1990-06-26 Institut Fur Molekularbiologie Und Analytik (Ima) G.M.B.H. 2',3'-dideoxyribofuranosides and process for producing them
JP2619710B2 (ja) * 1989-02-27 1997-06-11 日本製紙 株式会社 2′,3′−ジデオキシプリンヌクレオシド類の製造方法
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
US5013829A (en) * 1989-04-26 1991-05-07 University Of Iowa Research Foundation Stable congener of 2',3'-dideoxyadenosine
DE4020529A1 (de) * 1989-09-12 1991-03-21 Roxana Vasiloiu Multifunktionelle(s) enzym(e) mit nucleosid-didesoxyribosyltransferase(n) und/oder nucleoside-desoxyribosyltransferasen(n) und/oder kinease- und/oder reduktase- und/oder desaminase- und/oder polymerase-aktivitaet
JPH0637391B2 (ja) * 1989-09-29 1994-05-18 日本製紙株式会社 抗エイズウイルス剤
PT95516A (pt) * 1989-10-06 1991-08-14 Wellcome Found Processo para a preparacao de derivados de 2',3'-didesoxi nucleosidos 6-substituidos
WO1991012260A1 (en) * 1990-02-09 1991-08-22 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce 6-halo- and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
ATE254126T1 (de) * 1998-12-23 2003-11-15 Shire Biochem Inc Antivirale nukleosidanaloga
CN101220071B (zh) * 2008-01-17 2011-04-06 南京长澳医药科技有限公司 稳定的6-甲氧基-2’,3’-双脱氧鸟嘌呤核苷及其制备方法和包含它的药物组合物
CN102234280B (zh) * 2010-04-26 2014-01-08 北京大学 D,l-鸟嘌呤核苷类似物及其制备方法和应用
PE20140608A1 (es) 2010-09-22 2014-06-12 Alios Biopharma Inc Analogos de nucleotidos sustituidos
AU2012262021B2 (en) * 2011-06-01 2016-07-28 Janus Biotherapeutics, Inc. Novel immune system modulators
CA2860234A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
NZ631601A (en) 2012-03-21 2016-06-24 Alios Biopharma Inc Solid forms of a thiophosphoramidate nucleotide prodrug
US9012427B2 (en) 2012-03-22 2015-04-21 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
RU2015137298A (ru) * 2013-03-05 2017-04-10 Ф. Хоффманн-Ля Рош Аг Ингибиторы тирозинкиназы брутона

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573777A (en) * 1977-11-03 1980-08-28 Wellcome Found 9-d-arabinonucleosides and an enzymatic process for their preparation
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
AU572019B2 (en) * 1985-03-16 1988-04-28 Wellcome Foundation Limited, The 3'-azido-3'-deoxythymidine
AU591125B2 (en) * 1985-05-15 1989-11-30 Wellcome Foundation Limited, The Therapeutic nucleosides
JPS62501777A (ja) * 1985-08-26 1987-07-16 アメリカ合衆国 2′,3′―ジデオキシシチジンを含有する抗htlv―3/lav剤
EP0217580A3 (en) * 1985-09-17 1990-11-07 The Wellcome Foundation Limited Therapeutic nucleosides
IT1203558B (it) * 1986-05-20 1989-02-15 Firestone Int Dev Spa Metodo per la realizzazione di un pneumatico radiale di prima fase per veicoli
AU613026B2 (en) * 1987-03-24 1991-07-25 Nycomed As 2',3' dideoxyribofuranoxide derivatives
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
IL87149A (en) * 1987-07-20 1994-05-30 Merck & Co Inc 6-Piperazinyl derivatives of purine and its 3- and 9-deaza isosteres, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO171641B (no) 1993-01-04
CA1326237C (en) 1994-01-18
CS242188A2 (en) 1990-09-12
EP0286425A2 (en) 1988-10-12
AP78A (en) 1990-03-12
NO881537L (no) 1988-10-10
EP0286425A3 (en) 1990-12-05
EP0286425B1 (en) 1995-01-11
DE3852710D1 (de) 1995-02-23
PL154956B1 (en) 1991-10-31
ATE116984T1 (de) 1995-01-15
JPS63267796A (ja) 1988-11-04
DE3852710T2 (de) 1995-05-24
MC1915A1 (fr) 1989-04-06
NZ224189A (en) 1991-09-25
AU1444488A (en) 1988-10-13
KR880012630A (ko) 1988-11-28
AP8800086A0 (en) 1988-02-01
FI881651A0 (fi) 1988-04-08
RU1779256C (ru) 1992-11-30
IL86007A0 (en) 1988-09-30
FI87214C (fi) 1992-12-10
PL271722A1 (en) 1989-01-23
NO881537D0 (no) 1988-04-08
PT87191A (pt) 1988-05-01
CS274461B2 (en) 1991-04-11
PT87191B (pt) 1993-02-26
JP2763888B2 (ja) 1998-06-11
AU608590B2 (en) 1991-04-11
HUT48269A (en) 1989-05-29
NO171641C (no) 1993-04-14
DK191688A (da) 1988-10-10
FI87214B (fi) 1992-08-31
HU201954B (en) 1991-01-28
US5068320A (en) 1991-11-26
DK191688D0 (da) 1988-04-08

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: THE WELLCOME FOUNDATION LIMITED