FI873467A - Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat - Google Patents

Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat Download PDF

Info

Publication number
FI873467A
FI873467A FI873467A FI873467A FI873467A FI 873467 A FI873467 A FI 873467A FI 873467 A FI873467 A FI 873467A FI 873467 A FI873467 A FI 873467A FI 873467 A FI873467 A FI 873467A
Authority
FI
Finland
Prior art keywords
amino
cycloalkyl
aryl
lower alkyl
preparation
Prior art date
Application number
FI873467A
Other languages
English (en)
Finnish (fi)
Other versions
FI873467A0 (sv
FI90762C (sv
FI90762B (sv
Inventor
Peter Herold
Christof Angst
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of FI873467A0 publication Critical patent/FI873467A0/sv
Publication of FI873467A publication Critical patent/FI873467A/sv
Application granted granted Critical
Publication of FI90762B publication Critical patent/FI90762B/sv
Publication of FI90762C publication Critical patent/FI90762C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/26—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI873467A 1986-08-13 1987-08-10 Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat FI90762C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH324886 1986-08-13
CH324886 1986-08-13

Publications (4)

Publication Number Publication Date
FI873467A0 FI873467A0 (sv) 1987-08-10
FI873467A true FI873467A (sv) 1988-02-14
FI90762B FI90762B (sv) 1993-12-15
FI90762C FI90762C (sv) 1994-03-25

Family

ID=4251859

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873467A FI90762C (sv) 1986-08-13 1987-08-10 Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat

Country Status (14)

Country Link
US (2) US4898977A (sv)
EP (1) EP0258183B1 (sv)
JP (1) JP2571230B2 (sv)
KR (1) KR950013635B1 (sv)
AT (1) ATE86971T1 (sv)
DD (1) DD269148A5 (sv)
DE (1) DE3784812D1 (sv)
DK (1) DK420887A (sv)
ES (1) ES2053582T3 (sv)
FI (1) FI90762C (sv)
HU (3) HU200981B (sv)
IL (1) IL83497A (sv)
MX (1) MX7727A (sv)
PT (1) PT85520B (sv)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992562A (en) * 1985-08-09 1991-02-12 Pfizer Inc. Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues
US5076973A (en) * 1988-10-24 1991-12-31 Arizona Board Of Regents Synthesis of dolastatin 3
AU629867B2 (en) * 1988-11-17 1992-10-15 Imperial Chemical Industries Plc Triazolo (4,3a) pyrazine derivatives
GB8912659D0 (en) * 1989-06-02 1989-07-19 Ici Plc Process
GB8927915D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Novel alcohols
DE4008403A1 (de) * 1990-03-16 1991-09-19 Merck Patent Gmbh Glykolsaeurederivate
US5436339A (en) * 1991-03-06 1995-07-25 Abbott Laboratories Process for the preparation of a substituted diaminoalcohol
EP0546230A1 (en) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Novel process for preparing 4-amino-5-hexenoic acid
US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
AU688403B2 (en) * 1993-11-03 1998-03-12 Commonwealth Scientific And Industrial Research Organisation Allylic chain transfer agents
US5977278A (en) * 1993-11-03 1999-11-02 E. I. Du Pont De Nemours And Company Polymers formed from allylic chain transfer agents
IL111484A (en) * 1993-11-03 2001-06-14 Commw Scient Ind Res Org Polymerization process using pendant chain transfer means to regulate the molecular weight, the polymers thus obtained and a number of new pesticide compounds
US5475138A (en) * 1994-07-07 1995-12-12 Pharm-Eco Laboratories Incorporated Method preparing amino acid-derived diaminopropanols
US5473104A (en) * 1994-09-13 1995-12-05 Neurocrine Biosciences, Inc. Process for the preparation of L-carnitine
US5760019A (en) * 1996-07-12 1998-06-02 The Research Foundation Of State University Of New York Silanol enzyme inhibitors
US6833460B2 (en) * 1999-06-18 2004-12-21 E. I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
US6423850B1 (en) 1999-06-18 2002-07-23 E.I. Du Pont De Nemours And Company Preparation and use of gamma-butyrolactones as cross-linking agents
US7312247B2 (en) * 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7057057B2 (en) * 2002-05-22 2006-06-06 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US8026280B2 (en) * 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
JP2006508986A (ja) * 2002-11-20 2006-03-16 エルラント ゲネ セラペウチクス エルエルシー ヒストンデアセチラーゼ阻害剤による肺細胞の治療方法
US20060160902A1 (en) * 2004-11-08 2006-07-20 Wiech Norbert L Histone deacetylase inhibitors
CN101160281A (zh) * 2005-04-06 2008-04-09 特瓦制药工业有限公司 结晶形态的普瑞巴林
CN101300224A (zh) * 2005-04-11 2008-11-05 特瓦制药工业有限公司 制备(s)-普瑞巴林的方法
US7488846B2 (en) * 2005-04-11 2009-02-10 Teva Pharmaceuical Industries Ltd. Pregabalin free of lactam and a process for preparation thereof
MX2007000525A (es) * 2005-05-10 2007-03-28 Teva Pharma Pregabalina libre de acido isobutilglutarico y un proceso para la preparacion de ella.
DE602006017995D1 (de) * 2005-05-10 2010-12-16 Teva Pharma Verfahren zur herstellung von pregabalin und salzen daraus
EP1879854B1 (en) * 2005-05-10 2011-09-07 Teva Pharmaceutical Industries Ltd Optical resolution of 3-carbamoylmethyl-5-methyl hexanoic acid
WO2007035890A1 (en) * 2005-09-19 2007-03-29 Teva Pharmaceutical Industries Ltd. An asymmetric synthesis of ( s ) - ( + ) -3- (aminomethyl) -5-methylhexanoic acid
US7462738B2 (en) * 2006-05-24 2008-12-09 Teva Pharmaceutical Industries Ltd. Processes for the preparation of R-(+)-3-(carbamoyl methyl)-5-methylhexanoic acid and salts thereof
EP2071032A3 (en) * 2006-05-31 2009-07-08 Teva Pharmaceutical Industries Ltd The use of enzymatic resolution for the preparation of intermediates of pregabalin
WO2007143152A2 (en) * 2006-05-31 2007-12-13 Teva Pharmaceutical Industries Ltd. Preparation of (s)-pregabalin-nitrile
MX2008014759A (es) * 2007-03-22 2009-03-09 Teva Pharma Sintesis del acido (s)-(+)-3-(aminometil)-5-metil hexanoico.
DE102007049039A1 (de) 2007-10-11 2009-04-16 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung
KR20100107500A (ko) * 2008-06-23 2010-10-05 테바 파마슈티컬 인더스트리즈 리미티드 (ｓ) 또는 (ｒ)-이소-부틸-글루타릭 에스테르의 입체선택적 효소 합성방법
US8257462B2 (en) * 2009-10-15 2012-09-04 Federal-Mogul Corporation Iron-based sintered powder metal for wear resistant applications
JP5585172B2 (ja) * 2010-04-05 2014-09-10 三菱瓦斯化学株式会社 脂環式エステル化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB960005A (en) * 1961-01-18 1964-06-10 Distillers Co Yeast Ltd Production of acrylic and methacrylic esters
DE1914380A1 (de) * 1969-03-21 1970-10-01 Basf Ag Verfahren zur Herstellung von Buta-1,3-dien-1-carbonsaeurealkylestern
US4031115A (en) * 1976-03-29 1977-06-21 Chevron Research Company 4-Pentenoic acid conversion
CH634815A5 (fr) * 1978-08-30 1983-02-28 Firmenich & Cie Procede pour la preparation d'esters et acides gamma, delta-insatures.
US4372974A (en) * 1980-06-25 1983-02-08 New York University Anticonvulsive compositions and method of treating convulsive disorders
US4609643A (en) * 1980-08-06 1986-09-02 Aktiebolaget Hassle Renin inhibitors, treatments and dipeptide synthesis
US4487963A (en) * 1983-01-03 1984-12-11 Merck & Co., Inc. Enantioselective synthesis of 4-amino-3-hydroxy-2,4-(disubstituted)pentanoic acid
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
FI88400C (sv) * 1984-08-06 1993-05-10 Upjohn Co Förfarande för framställning av renin inhiberande peptider
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
US4665055A (en) * 1985-06-17 1987-05-12 Merck & Co., Inc. Peptide renin inhibitors
HU204285B (en) * 1986-10-31 1991-12-30 Pfizer Process for producing renin-inhibiting polypeptides of small molecule mass and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
KR880002808A (ko) 1988-05-11
US5010189A (en) 1991-04-23
US4898977A (en) 1990-02-06
HU200981B (en) 1990-09-28
HUT44478A (en) 1988-03-28
JPS6357561A (ja) 1988-03-12
PT85520A (en) 1987-09-01
MX7727A (es) 1993-12-01
ES2053582T3 (es) 1994-08-01
EP0258183B1 (de) 1993-03-17
KR950013635B1 (ko) 1995-11-13
FI873467A0 (sv) 1987-08-10
DD269148A5 (de) 1989-06-21
FI90762C (sv) 1994-03-25
HU198445B (en) 1989-10-30
IL83497A0 (en) 1988-01-31
DK420887D0 (da) 1987-08-12
IL83497A (en) 1993-02-21
EP0258183A3 (en) 1989-07-26
PT85520B (pt) 1990-06-29
HU202218B (en) 1991-02-28
FI90762B (sv) 1993-12-15
ATE86971T1 (de) 1993-04-15
EP0258183A2 (de) 1988-03-02
JP2571230B2 (ja) 1997-01-16
DE3784812D1 (de) 1993-04-22
DK420887A (da) 1988-02-14

Similar Documents

Publication Publication Date Title
FI873467A (sv) Förfarande för framställning av 5-amino-4-hydroxi-valeriansyraderivat
GR3008221T3 (sv)
DE3650518D1 (de) Beta-Lactamantibiotika, Verfahren zur Herstellung und ihre Verwendung als und in Arzneimitteln
ATE140920T1 (de) Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung
AT383123B (de) Verfahren zur herstellung von neuen (+)-catechin- alpha- monohydrat
ATE51617T1 (de) Verfahren zur herstellung von 4-phenyl-pyrrolderivaten.
DE3667059D1 (en) Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds
ES2058176T3 (es) Un procedimiento para preparar un derivado peptidico.
DK226285A (da) Beta-lactamforbindelser, deres fremstilling og anvendelse som laegemidler eller vaekstfremmende midler til dyr samt mellemprodukter til fremstillingen
PL250150A1 (en) Process for preparing novel muramyl peptides
DK383388D0 (da) 3-demethyl-4-fluor-mevalonsyrederivater, deres fremstilling, farmaceutiske praeparater deraf, deres anvendelse og mellemprodukter til deres fremstilling
ATE14126T1 (de) Verfahren zur herstellung von 2-acyl1,3,4,6,7,11b-2h-hexahydro-4-pyrazino(2,1a)isochinolinonen und zwischenprodukte.
ATE48594T1 (de) Verfahren zur herstellung von acylurethanen und deren verwendung.
AU2021988A (en) Novel compounds and processes for synthesis thereof
ATE76408T1 (de) Carbapenem-antibiotika, ein verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
EP0269514A3 (en) Derivatives of 2,2-dimethylcyclopropanecarboxylic acid bearing a saturated halogenated chain at c-3, process and intermediates for their preparation, their use as pesticides and compositions containing them
SE8301928D0 (sv) Nya karbapenemderivat och forfarande for framstellning derav
ES2130392T3 (es) Procedimiento para la preparacion de acido clavulanico.
FR2633622B1 (fr) Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese
ATE39688T1 (de) Verfahren zur herstellung von aminotriazinonderivaten.
ES516584A0 (es) Mejoras introducidas en un procedimiento para la preparacion de hidroximidatos y tiolhidroximidatos heterobiciclicos y derivados ester carbamato de lso mismos.
ES2059644T3 (es) Esteres de acido 2,2-dimetil-ciclopropan-carboxilico.

Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

MM Patent lapsed
MM Patent lapsed

Owner name: NOVARTIS AG