FI872864A0 - Förfarande för framställning av farmaceutiskt aktiva bensimidazolföreningar - Google Patents

Förfarande för framställning av farmaceutiskt aktiva bensimidazolföreningar

Info

Publication number
FI872864A0
FI872864A0 FI872864A FI872864A FI872864A0 FI 872864 A0 FI872864 A0 FI 872864A0 FI 872864 A FI872864 A FI 872864A FI 872864 A FI872864 A FI 872864A FI 872864 A0 FI872864 A0 FI 872864A0
Authority
FI
Finland
Prior art keywords
preparation
pharmaceutically active
benzimidazole derivatives
active benzimidazole
compounds
Prior art date
Application number
FI872864A
Other languages
English (en)
Finnish (fi)
Other versions
FI872864A (sv
FI91151B (sv
FI91151C (sv
Inventor
Tomas Boerje Alminger
Haokan Sigurd Larsson
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of FI872864A0 publication Critical patent/FI872864A0/sv
Publication of FI872864A publication Critical patent/FI872864A/sv
Publication of FI91151B publication Critical patent/FI91151B/sv
Application granted granted Critical
Publication of FI91151C publication Critical patent/FI91151C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
FI872864A 1985-10-29 1987-06-29 Förfarande för framställning av farmaceutiskt aktiva bensimidazolföreningar FI91151C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8505112A SE8505112D0 (sv) 1985-10-29 1985-10-29 Novel pharmacological compounds
SE8505112 1985-10-29
SE8600493 1986-10-28
PCT/SE1986/000493 WO1987002668A1 (en) 1985-10-29 1986-10-28 Novel pharmacological compounds

Publications (4)

Publication Number Publication Date
FI872864A0 true FI872864A0 (sv) 1987-06-29
FI872864A FI872864A (sv) 1987-06-29
FI91151B FI91151B (sv) 1994-02-15
FI91151C FI91151C (sv) 1994-05-25

Family

ID=20361960

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872864A FI91151C (sv) 1985-10-29 1987-06-29 Förfarande för framställning av farmaceutiskt aktiva bensimidazolföreningar

Country Status (31)

Country Link
US (1) US5021433A (sv)
EP (2) EP0233284B1 (sv)
JP (2) JPH0780874B2 (sv)
KR (1) KR950009858B1 (sv)
CN (1) CN1022487C (sv)
AT (1) ATE79619T1 (sv)
AU (1) AU598491B2 (sv)
CS (1) CS272767B2 (sv)
DD (1) DD252375A5 (sv)
DE (1) DE3686483T2 (sv)
DK (1) DK320587A (sv)
EG (1) EG17753A (sv)
ES (1) ES2051696T3 (sv)
FI (1) FI91151C (sv)
GR (1) GR3006177T3 (sv)
HU (1) HU198474B (sv)
IE (1) IE59167B1 (sv)
IL (1) IL80437A0 (sv)
IS (1) IS1564B (sv)
JO (1) JO1502B1 (sv)
LT (1) LTIP1681A (sv)
LV (1) LV10270B (sv)
MY (1) MY101791A (sv)
NO (1) NO171365C (sv)
NZ (1) NZ218028A (sv)
PH (1) PH25319A (sv)
PL (1) PL150240B1 (sv)
PT (1) PT83647B (sv)
SE (1) SE8505112D0 (sv)
WO (1) WO1987002668A1 (sv)
ZA (1) ZA867716B (sv)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222495A (en) * 1986-11-21 1991-04-26 Haessle Ab Benzimidazole derivatives and pharmaceutical compositions
AU617217B2 (en) * 1988-09-20 1991-11-21 Hisamitsu Pharmaceutical Co., Inc. Novel dibenz(b,e)oxepin derivatives
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ES2048109B1 (es) * 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
WO1995032957A1 (en) * 1994-05-27 1995-12-07 Astra Aktiebolag Novel ethoxycarbonyloxymethyl derivatives of substituted benzimidazoles
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
NZ510180A (en) 1998-08-10 2002-11-26 Univ California Prodrugs of the pyridyl-methylsulphonyl-benzimidazole type proton pump inhibitors
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
WO2002030920A1 (fr) * 2000-10-12 2002-04-18 Takeda Chemical Industries, Ltd. Composes derives de benzimidazole, leur procede de production et leur utilisation
WO2003027098A1 (fr) * 2001-09-25 2003-04-03 Takeda Chemical Industries, Ltd. Compose de benzymidazole, procede de production et d'utilisation de celui-ci
MXPA04012396A (es) * 2002-06-14 2005-06-17 Sato Fumihiko Compuestos de imidazol, metodos y uso para la produccion de los mismos.
CA2492718C (en) * 2002-07-19 2010-12-21 Michael E. Garst Prodrugs of proton pump inhibitors
CA2493618A1 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
US8802139B2 (en) * 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US20060241037A1 (en) * 2003-10-03 2006-10-26 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump ihhibitor prodrugs
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
BRPI0507784A (pt) * 2004-02-18 2007-07-17 Allergan Inc métodos e composições para a administração de pró-fármacos de inibidores da bomba de prótons
CA2557471A1 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Methods and compositions for the intravenous administration of compounds related to proton pump inhibitors
US20050239845A1 (en) * 2004-04-16 2005-10-27 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
DK1740571T3 (da) 2004-04-28 2009-11-02 Hetero Drugs Ltd Fremgangsmåde til fremstilling af pyridinylmethyl-1H-benzimidazolforbindelser i enantiomerisk beriget form eller som enkelte enantiomerer
PT1748998E (pt) 2004-05-28 2010-03-24 Hetero Drugs Ltd Novo processo de síntese estereoselectiva de sulfóxidos de benzimidazol
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CA2648280C (en) * 2006-04-03 2014-03-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008036201A1 (en) * 2006-09-19 2008-03-27 Alevium Pharmaceuticals, Inc. Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
WO2009105568A1 (en) 2008-02-20 2009-08-27 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
EP2521545B1 (en) * 2010-01-07 2019-11-27 Alkermes Pharma Ireland Limited Prodrugs of heteroaromatic compounds

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR320097A (fr) * 1902-04-01 1902-12-01 Betts Perfectionnements dans et relatifs au raffinage électrolytique du plomb et des alliages de plomb
FR1474663A (fr) * 1966-04-06 1967-03-24 Electrolyt Zinc Australasia Procédé d'extraction de métaux
US4026776A (en) * 1970-12-02 1977-05-31 Mitsui Mining & Smelting Co., Ltd. Method for producing high purity lead
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
US3960681A (en) * 1974-02-21 1976-06-01 Mitsui Mining & Smelting Co., Ltd. Method for producing electrolytic high purity lead using large-sized electrodes
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
NZ181123A (en) * 1975-06-30 1979-12-11 Univ Melbourne Treatment of mineralcontaining materials with an acid in the presence of fluoride ion
US3972790A (en) * 1975-09-26 1976-08-03 Uop Inc. Production of metallic lead
IN148930B (sv) * 1977-09-19 1981-07-25 Hoffmann La Roche
US4189461A (en) * 1977-11-30 1980-02-19 Kennecott Copper Corporation Metal leaching from concentrates using nitrogen dioxide in acids
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
FR2446863A1 (fr) * 1979-01-22 1980-08-14 Uop Inc Procede perfectionne de recuperation de plomb
FR2453906A1 (fr) * 1979-04-12 1980-11-07 Uop Inc Procede de preparation hydrometallurgique de plomb a l'aide d'une extraction par voie electrochimique
US4229271A (en) * 1979-05-24 1980-10-21 Rsr Corporation Method of recovering lead values from battery sludge
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
FR2505876A1 (en) * 1981-05-12 1982-11-19 Noual Patrick Selective winning of lead from sulphide ores - by leaching with hot aq. hydro:fluorosilicic acid soln. contg. hydrogen peroxide and air so only lead is dissolved
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
US4500398A (en) * 1984-06-20 1985-02-19 The United States Of America As Represented By The Secretary Of The Interior Production of lead from sulfides
ZA856671B (en) * 1984-09-24 1986-04-30 Upjohn Co N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives

Also Published As

Publication number Publication date
PT83647A (en) 1986-11-01
CN1022487C (zh) 1993-10-20
JO1502B1 (en) 1989-01-25
LTIP1681A (en) 1995-09-25
EP0233284B1 (en) 1992-08-19
CN86107595A (zh) 1987-07-08
NO171365B (no) 1992-11-23
EP0221041A2 (en) 1987-05-06
ES2051696T3 (es) 1994-07-01
NO872686L (no) 1987-06-26
IL80437A0 (en) 1987-01-30
CS782686A2 (en) 1990-05-14
EP0221041A3 (en) 1987-10-28
EG17753A (en) 1991-12-30
NZ218028A (en) 1990-02-26
US5021433A (en) 1991-06-04
KR870700620A (ko) 1987-12-30
PL150240B1 (en) 1990-05-31
DE3686483T2 (de) 1993-02-04
IS3156A7 (is) 1987-04-30
JPS63501151A (ja) 1988-04-28
DE3686483D1 (de) 1992-09-24
NO872686D0 (no) 1987-06-26
DK320587D0 (da) 1987-06-24
MY101791A (en) 1992-01-31
JPH0780874B2 (ja) 1995-08-30
KR950009858B1 (ko) 1995-08-29
DD252375A5 (de) 1987-12-16
WO1987002668A1 (en) 1987-05-07
DK320587A (da) 1987-06-24
IE862805L (en) 1987-04-29
CS272767B2 (en) 1991-02-12
SE8505112D0 (sv) 1985-10-29
GR3006177T3 (sv) 1993-06-21
LV10270B (en) 1995-04-20
JPH0826014B2 (ja) 1996-03-13
FI872864A (sv) 1987-06-29
ZA867716B (en) 1987-05-27
ATE79619T1 (de) 1992-09-15
JPH07188216A (ja) 1995-07-25
EP0233284A1 (en) 1987-08-26
HUT43843A (en) 1987-12-28
NO171365C (no) 1993-03-03
AU598491B2 (en) 1990-06-28
PT83647B (pt) 1989-05-31
PH25319A (sv) 1991-04-30
HU198474B (en) 1989-10-30
PL262105A1 (en) 1988-08-18
IS1564B (is) 1994-12-13
FI91151B (sv) 1994-02-15
FI91151C (sv) 1994-05-25
AU6542986A (en) 1987-05-19
LV10270A (lv) 1994-10-20
IE59167B1 (en) 1994-01-12

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: AKTIEBOLAGET HAESSLE