FI871910A - Foerfarande foer framstaellning av heparin med laog molekylvikt. - Google Patents

Foerfarande foer framstaellning av heparin med laog molekylvikt. Download PDF

Info

Publication number
FI871910A
FI871910A FI871910A FI871910A FI871910A FI 871910 A FI871910 A FI 871910A FI 871910 A FI871910 A FI 871910A FI 871910 A FI871910 A FI 871910A FI 871910 A FI871910 A FI 871910A
Authority
FI
Finland
Prior art keywords
molekylvikt
heparin
foerfarande foer
foer framstaellning
med laog
Prior art date
Application number
FI871910A
Other languages
English (en)
Other versions
FI90090C (fi
FI90090B (fi
FI871910A0 (fi
Inventor
Jorgen Ilum Nielsen
Per Bjorn Ostergaord
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of FI871910A0 publication Critical patent/FI871910A0/fi
Publication of FI871910A publication Critical patent/FI871910A/fi
Application granted granted Critical
Publication of FI90090B publication Critical patent/FI90090B/fi
Publication of FI90090C publication Critical patent/FI90090C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
FI871910A 1986-04-30 1987-04-29 Foerfarande foer framstaellning av heparin med laog molekylvikt FI90090C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK196986A DK196986D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider
DK196986 1986-04-30

Publications (4)

Publication Number Publication Date
FI871910A0 FI871910A0 (fi) 1987-04-29
FI871910A true FI871910A (fi) 1987-10-31
FI90090B FI90090B (fi) 1993-09-15
FI90090C FI90090C (fi) 1993-12-27

Family

ID=8109197

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871910A FI90090C (fi) 1986-04-30 1987-04-29 Foerfarande foer framstaellning av heparin med laog molekylvikt

Country Status (7)

Country Link
EP (1) EP0244236A3 (fi)
JP (1) JPS62283103A (fi)
AU (1) AU588102B2 (fi)
CA (1) CA1334081C (fi)
DK (1) DK196986D0 (fi)
FI (1) FI90090C (fi)
NO (1) NO167208C (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214609B (it) * 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
NL8900119A (nl) * 1989-01-19 1990-08-16 Akzo Nv Werkwijze voor het afsplitsen van (delta)4-onverzadigd uronzuur in glycosaminoglycaan fragmenten.
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
KR100512671B1 (ko) * 1996-11-27 2005-09-07 아벤티스 파마슈티칼스 인크. 항 Ｘａ 활성을 지닌 화합물 및 혈소판 응집 길항제 화합물을포함하는 약제학적 조성물
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
CA2402160C (en) 2000-03-08 2012-02-14 Massachusetts Institute Of Technology Heparinase iii and uses thereof
JP4911865B2 (ja) 2000-09-12 2012-04-04 マサチューセッツ インスティテュート オブ テクノロジー 低分子量ヘパリンに関連する方法および生成物
JP2004523479A (ja) 2000-10-18 2004-08-05 マサチューセッツ　インスティテュート　オブ　テクノロジー 多糖の肺送達に関する方法および産物
EP2284535A1 (en) 2002-03-11 2011-02-16 Momenta Pharmaceuticals, Inc. Low molecular weight heparins
EP1582531A1 (en) * 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
EP2019843A2 (en) * 2006-05-25 2009-02-04 Momenta Pharmaceuticals, Inc. Low molecular weight heparin composition and uses thereof
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
US8435795B2 (en) 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN103214596A (zh) * 2013-05-14 2013-07-24 枣庄赛诺康生化股份有限公司 由肝素钠粗品直接生产低分子量肝素钠的方法
CN103323416A (zh) * 2013-07-04 2013-09-25 苏州良辰生物医药科技有限公司 一种肝素浓度的测定方法
CN108117614B (zh) * 2016-11-29 2020-09-04 北京碧澄生物科技有限公司 低分子量肝素
BR112022000255A8 (pt) 2019-07-09 2022-03-22 Optimvia Llc Métodos para sintetizar polissacarídeos anticoagulantes
EP4182452A4 (en) 2020-07-14 2024-07-31 Optimvia Llc METHOD FOR THE SYNTHESIS OF NON-ANTICOAGULATING HEPARAN SULFATE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4396762A (en) * 1981-08-24 1983-08-02 Massachusetts Institute Of Technology Heparinase derived anticoagulants
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider

Also Published As

Publication number Publication date
FI90090C (fi) 1993-12-27
NO871783D0 (no) 1987-04-29
NO167208C (no) 1991-10-16
EP0244236A3 (en) 1988-09-28
DK196986D0 (da) 1986-04-30
FI90090B (fi) 1993-09-15
AU7225587A (en) 1987-11-05
AU588102B2 (en) 1989-09-07
JPH0542919B2 (fi) 1993-06-30
EP0244236A2 (en) 1987-11-04
CA1334081C (en) 1995-01-24
FI871910A0 (fi) 1987-04-29
NO167208B (no) 1991-07-08
NO871783L (no) 1987-11-02
JPS62283103A (ja) 1987-12-09

Similar Documents

Publication Publication Date Title
FI86241B (fi) Foerfarande foer oeverfoering av bildsignaler med hjaelp av transformationskodning.
FI871872A (fi) Logik foer minskning av hastigheten foer vindturbin med reglerbar stigning.
FI871930A0 (fi) Kroppar med laog ytmotstaond.
FI871910A0 (fi) Foerfarande foer framstaellning av heparin med laog molekylvikt.
FI864649A (fi) Short-dwell-bestrykningsanordning foer bestrykning av en materialbana med bestrykningsmassa.
FI875079A0 (fi) Fettsyrafoereningar med isocyanatkarboxylgrupper foer framstaellning av cellulosablandningar.
FI873865A0 (fi) Metallisk bikakekatalysatorbaerare med dubbelkon.
FI873024A (fi) Isolationsskiva av skumplast beklaedd med polymer- och fiberlaminat.
FI870043A (fi) Foerfarande foer laddning av uppaotgaoende borrhaol med flytbara explosiva aemnen.
FI871174A0 (fi) Foerfarande foer bestaemning av haptener med hjaelp av immunoanalysteknik.
FI864526A0 (fi) Foerfarande foer tillvaratagande av vaerme i samband med en gasturbinprocess.
FI875205A0 (fi) Foerfarande foer blandning av medier med olika viskositet.
FI883690A (fi) Med kombinationsfrontskiva foersett televisionsbildroer.
FI865301A0 (fi) Med en fresnel-lins foersedd kaopa foer belysningsanordning.
FI872889A0 (fi) Foerfarande foer framstaellning av med en kolvaetekedja ympade cellulosafibrer.
FI870724A (fi) Kraftanlaeggning med renare av centrifugaltyp foer foerbraenningsgaser.
FI872290A (fi) Byggelement foer en med kaerna foersedd skida.
FI860263A (fi) Med undertryck fungerande faestunderlag.
FI864309A0 (fi) Genompigmentering av plastaemne med paerlemorpigment.
FI860363A0 (fi) Foerfarande foer formning av metall- och metallfoereningsbelaeggningar med hjaelp av kemisk gasfasbelaeggning.
FI863862A0 (fi) Faeststomme foersedd med sidofoerskjutning av krok.
FI865093A0 (fi) Utrustande av ordfoerandeklubba med spraengladdning.
FI865072A0 (fi) Kopplingsanordning foer hopkoppling av tvao med varandra gaongjaernsfoerbunda foensterbaogar.
FI863715A0 (fi) Foerfarande foer behandling av fibermassa med kemikalieloesning.
FI891616A (fi) Arrangemang i samband med en lindragningsanordning i aendan av en transportlinje.

Legal Events

Date Code Title Description
FG Patent granted

Owner name: NOVO NORDISK A/S

BB Publication of examined application
FG Patent granted

Owner name: NOVO NORDISK A/S

MA Patent expired