NO167208C - Fremgangsmaate for fremstilling av heparin med lav molekylvekt (lmv-heparin). - Google Patents

Fremgangsmaate for fremstilling av heparin med lav molekylvekt (lmv-heparin).

Info

Publication number
NO167208C
NO167208C NO871783A NO871783A NO167208C NO 167208 C NO167208 C NO 167208C NO 871783 A NO871783 A NO 871783A NO 871783 A NO871783 A NO 871783A NO 167208 C NO167208 C NO 167208C
Authority
NO
Norway
Prior art keywords
lmv
heparin
procedure
molecular weight
low molecular
Prior art date
Application number
NO871783A
Other languages
English (en)
Other versions
NO871783L (no
NO871783D0 (no
NO167208B (no
Inventor
Joergen Ilum Nielsen
Per Bjoern Oestergaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO871783D0 publication Critical patent/NO871783D0/no
Publication of NO871783L publication Critical patent/NO871783L/no
Publication of NO167208B publication Critical patent/NO167208B/no
Publication of NO167208C publication Critical patent/NO167208C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
NO871783A 1986-04-30 1987-04-29 Fremgangsmaate for fremstilling av heparin med lav molekylvekt (lmv-heparin). NO167208C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK196986A DK196986D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider

Publications (4)

Publication Number Publication Date
NO871783D0 NO871783D0 (no) 1987-04-29
NO871783L NO871783L (no) 1987-11-02
NO167208B NO167208B (no) 1991-07-08
NO167208C true NO167208C (no) 1991-10-16

Family

ID=8109197

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871783A NO167208C (no) 1986-04-30 1987-04-29 Fremgangsmaate for fremstilling av heparin med lav molekylvekt (lmv-heparin).

Country Status (7)

Country Link
EP (1) EP0244236A3 (no)
JP (1) JPS62283103A (no)
AU (1) AU588102B2 (no)
CA (1) CA1334081C (no)
DK (1) DK196986D0 (no)
FI (1) FI90090C (no)
NO (1) NO167208C (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214609B (it) * 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
NL8900119A (nl) * 1989-01-19 1990-08-16 Akzo Nv Werkwijze voor het afsplitsen van (delta)4-onverzadigd uronzuur in glycosaminoglycaan fragmenten.
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
IL129877A (en) * 1996-11-27 2004-08-31 Aventis Pharm Prod Inc A pharmaceutical preparation containing a component having an Xa antagonist activity and an antifouling agent
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
EP1109919A2 (en) 1998-08-27 2001-06-27 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase i and ii
WO2000065521A2 (en) 1999-04-23 2000-11-02 Massachusetts Institute Of Technology System and method for polymer notation
AU2001243512C1 (en) 2000-03-08 2008-04-17 Massachusetts Institute Of Technology Heparinase III and uses thereof
DK1319183T3 (da) 2000-09-12 2009-05-18 Massachusetts Inst Technology Fremgangsmåder og produkter relateret til heparin med lav molekylvægt
EP1328260A2 (en) 2000-10-18 2003-07-23 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
JP4828795B2 (ja) 2002-03-11 2011-11-30 モメンタ ファーマシューティカルズ インコーポレイテッド 硫酸化多糖類の分析
EP1582531A1 (en) * 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
CA2652205A1 (en) * 2006-05-25 2007-12-06 Mallik Sundaram Low molecular weight heparin composition and uses thereof
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
RU2377993C2 (ru) * 2007-11-08 2010-01-10 Государственное учреждение гематологический научный центр Российской академии медицинских наук (ГУ ГНЦ РАМН) Способ получения низкомолекулярного гепарина
US8435795B2 (en) 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN103214596A (zh) * 2013-05-14 2013-07-24 枣庄赛诺康生化股份有限公司 由肝素钠粗品直接生产低分子量肝素钠的方法
CN103323416A (zh) * 2013-07-04 2013-09-25 苏州良辰生物医药科技有限公司 一种肝素浓度的测定方法
CN108117614B (zh) * 2016-11-29 2020-09-04 北京碧澄生物科技有限公司 低分子量肝素
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
EP3997238A1 (en) 2019-07-09 2022-05-18 Optimvia, LLC Methods for synthesizing anticoagulant polysaccharides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4396762A (en) * 1981-08-24 1983-08-02 Massachusetts Institute Of Technology Heparinase derived anticoagulants
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider

Also Published As

Publication number Publication date
AU588102B2 (en) 1989-09-07
FI90090B (fi) 1993-09-15
DK196986D0 (da) 1986-04-30
NO871783L (no) 1987-11-02
FI871910L (fi) 1987-10-31
FI90090C (fi) 1993-12-27
AU7225587A (en) 1987-11-05
CA1334081C (en) 1995-01-24
JPS62283103A (ja) 1987-12-09
NO871783D0 (no) 1987-04-29
EP0244236A2 (en) 1987-11-04
FI871910A0 (fi) 1987-04-29
EP0244236A3 (en) 1988-09-28
JPH0542919B2 (no) 1993-06-30
NO167208B (no) 1991-07-08

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