FI871910A0 - Foerfarande foer framstaellning av heparin med laog molekylvikt. - Google Patents

Foerfarande foer framstaellning av heparin med laog molekylvikt.

Info

Publication number
FI871910A0
FI871910A0 FI871910A FI871910A FI871910A0 FI 871910 A0 FI871910 A0 FI 871910A0 FI 871910 A FI871910 A FI 871910A FI 871910 A FI871910 A FI 871910A FI 871910 A0 FI871910 A0 FI 871910A0
Authority
FI
Finland
Prior art keywords
molekylvikt
heparin
foerfarande foer
foer framstaellning
med laog
Prior art date
Application number
FI871910A
Other languages
English (en)
Other versions
FI871910A (fi
FI90090C (fi
FI90090B (fi
Inventor
Jorgen Ilum Nielsen
Per Bjorn Ostergaord
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of FI871910A0 publication Critical patent/FI871910A0/fi
Publication of FI871910A publication Critical patent/FI871910A/fi
Application granted granted Critical
Publication of FI90090B publication Critical patent/FI90090B/fi
Publication of FI90090C publication Critical patent/FI90090C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
FI871910A 1986-04-30 1987-04-29 Foerfarande foer framstaellning av heparin med laog molekylvikt FI90090C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK196986A DK196986D0 (da) 1986-04-30 1986-04-30 Fremstilling af polysaccharider
DK196986 1986-04-30

Publications (4)

Publication Number Publication Date
FI871910A0 true FI871910A0 (fi) 1987-04-29
FI871910A FI871910A (fi) 1987-10-31
FI90090B FI90090B (fi) 1993-09-15
FI90090C FI90090C (fi) 1993-12-27

Family

ID=8109197

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871910A FI90090C (fi) 1986-04-30 1987-04-29 Foerfarande foer framstaellning av heparin med laog molekylvikt

Country Status (7)

Country Link
EP (1) EP0244236A3 (fi)
JP (1) JPS62283103A (fi)
AU (1) AU588102B2 (fi)
CA (1) CA1334081C (fi)
DK (1) DK196986D0 (fi)
FI (1) FI90090C (fi)
NO (1) NO167208C (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214609B (it) * 1985-05-17 1990-01-18 Opocrin Spa Esosaminoglicani solfati depolimerizzati ad attivita'antitrombotica, fibrinolitica, antinfiammatoria, loro procedimento di preparazione e composizioni farmaceutiche che li contengono.
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
NL8900119A (nl) * 1989-01-19 1990-08-16 Akzo Nv Werkwijze voor het afsplitsen van (delta)4-onverzadigd uronzuur in glycosaminoglycaan fragmenten.
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
AU754936B2 (en) * 1996-11-27 2002-11-28 Aventis Pharmaceuticals Inc. Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
AU4351201A (en) 2000-03-08 2001-09-17 Massachusetts Inst Technology Heparinase iii and uses thereof
PT1319183E (pt) 2000-09-12 2009-06-29 Massachusetts Inst Technology Métodos e produtos relacionados a heparina de baixo peso molecular
US7709461B2 (en) 2000-10-18 2010-05-04 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
US7575886B2 (en) 2002-03-11 2009-08-18 Momenta Pharmaceuticals, Inc. Analysis of sulfated polysaccharides
EP1582531A1 (en) * 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
CA2652205A1 (en) * 2006-05-25 2007-12-06 Mallik Sundaram Low molecular weight heparin composition and uses thereof
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
WO2011090948A1 (en) 2010-01-19 2011-07-28 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN103214596A (zh) * 2013-05-14 2013-07-24 枣庄赛诺康生化股份有限公司 由肝素钠粗品直接生产低分子量肝素钠的方法
CN103323416A (zh) * 2013-07-04 2013-09-25 苏州良辰生物医药科技有限公司 一种肝素浓度的测定方法
CN108117614B (zh) * 2016-11-29 2020-09-04 北京碧澄生物科技有限公司 低分子量肝素
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
EP3997238A1 (en) 2019-07-09 2022-05-18 Optimvia, LLC Methods for synthesizing anticoagulant polysaccharides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351938A (en) * 1980-05-19 1982-09-28 Riker Laboratories, Inc. Anticoagulant substance
US4396762A (en) * 1981-08-24 1983-08-02 Massachusetts Institute Of Technology Heparinase derived anticoagulants
DK196886D0 (da) * 1986-04-30 1986-04-30 Novo Industri As Fremstilling af polysaccharider

Also Published As

Publication number Publication date
JPS62283103A (ja) 1987-12-09
CA1334081C (en) 1995-01-24
NO871783L (no) 1987-11-02
DK196986D0 (da) 1986-04-30
FI871910A (fi) 1987-10-31
NO871783D0 (no) 1987-04-29
FI90090C (fi) 1993-12-27
NO167208C (no) 1991-10-16
EP0244236A3 (en) 1988-09-28
JPH0542919B2 (fi) 1993-06-30
FI90090B (fi) 1993-09-15
NO167208B (no) 1991-07-08
AU588102B2 (en) 1989-09-07
EP0244236A2 (en) 1987-11-04
AU7225587A (en) 1987-11-05

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Legal Events

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FG Patent granted

Owner name: NOVO NORDISK A/S

BB Publication of examined application
FG Patent granted

Owner name: NOVO NORDISK A/S

MA Patent expired