DE3778616D1 - Heparin-testverfahren. - Google Patents

Heparin-testverfahren.

Info

Publication number
DE3778616D1
DE3778616D1 DE8787902003T DE3778616T DE3778616D1 DE 3778616 D1 DE3778616 D1 DE 3778616D1 DE 8787902003 T DE8787902003 T DE 8787902003T DE 3778616 T DE3778616 T DE 3778616T DE 3778616 D1 DE3778616 D1 DE 3778616D1
Authority
DE
Germany
Prior art keywords
test procedure
heparin test
heparin
procedure
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787902003T
Other languages
English (en)
Inventor
Judah Folkman
L Hannan
S Langer
W Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Childrens Medical Center Corp
Massachusetts Institute of Technology
Original Assignee
Childrens Medical Center Corp
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center Corp, Massachusetts Institute of Technology filed Critical Childrens Medical Center Corp
Application granted granted Critical
Publication of DE3778616D1 publication Critical patent/DE3778616D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE8787902003T 1986-03-07 1987-03-05 Heparin-testverfahren. Expired - Lifetime DE3778616D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/837,517 US4795703A (en) 1986-03-07 1986-03-07 Heparin assay
PCT/US1987/000502 WO1987005333A1 (en) 1986-03-07 1987-03-05 Heparin assay

Publications (1)

Publication Number Publication Date
DE3778616D1 true DE3778616D1 (de) 1992-06-04

Family

ID=25274683

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787902003T Expired - Lifetime DE3778616D1 (de) 1986-03-07 1987-03-05 Heparin-testverfahren.

Country Status (6)

Country Link
US (1) US4795703A (de)
EP (1) EP0259463B1 (de)
JP (1) JP2632525B2 (de)
CA (1) CA1288673C (de)
DE (1) DE3778616D1 (de)
WO (1) WO1987005333A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262325A (en) * 1991-04-04 1993-11-16 Ibex Technologies, Inc. Method for the enzymatic neutralization of heparin
US5714376A (en) * 1991-10-23 1998-02-03 Massachusetts Institute Of Technology Heparinase gene from flavobacterium heparinum
US5389539A (en) 1992-11-30 1995-02-14 Massachusetts Institute Of Technology Purification of heparinase I, II, and III from Flavobacterium heparinum
US6346510B1 (en) * 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5925319A (en) 1996-04-30 1999-07-20 Medtronic, Inc. Test cartridge for evaluating blood platelet functionality
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
US7247488B2 (en) * 2003-05-06 2007-07-24 Medtronic, Inc. Method and kit for testing a multi-channel blood assay cartridge
ATE532058T1 (de) * 2004-05-17 2011-11-15 Medtronic Inc Point-of-care-heparinbestimmungssystem
DE102006035580A1 (de) * 2006-07-27 2008-02-14 Csl Behring Gmbh Bestimmung der biologischen Aktivität von Heparin in AT III-haltigen Präparationen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4067777A (en) * 1976-05-13 1978-01-10 Innerfield Irving Determination of heparin in the blood
JPS5477194A (en) * 1977-11-28 1979-06-20 Eichi Jiin Innaafuiirudo Method of measuring heparin in blood
JPS54107584A (en) * 1978-02-10 1979-08-23 Seikagaku Kogyo Co Ltd Preparation of pure heparinase
US4226599A (en) * 1979-06-20 1980-10-07 Warner-Lambert Company Removal of heparin from heparin-containing blood plasma samples using a triethylaminoethyl cellulose tablet
US4341869A (en) * 1980-08-25 1982-07-27 Massachusetts Institute Of Technology Process for producing heparinase
US4373023A (en) * 1980-10-14 1983-02-08 Massachusetts Institute Of Technology Process for neutralizing heparin

Also Published As

Publication number Publication date
JP2632525B2 (ja) 1997-07-23
CA1288673C (en) 1991-09-10
EP0259463B1 (de) 1992-04-29
EP0259463A1 (de) 1988-03-16
EP0259463A4 (de) 1988-07-14
JPS63503194A (ja) 1988-11-24
US4795703A (en) 1989-01-03
WO1987005333A1 (en) 1987-09-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition