FI840350A - Foerfarande foer racematisk avskiljning av optiskt aktiva bicykliska imino- -karbonsyraestrar och anvaendning av saolunda erhaollna foereningar till syntes av karboxialkyldipeptider. - Google Patents

Foerfarande foer racematisk avskiljning av optiskt aktiva bicykliska imino- -karbonsyraestrar och anvaendning av saolunda erhaollna foereningar till syntes av karboxialkyldipeptider. Download PDF

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Publication number
FI840350A
FI840350A FI840350A FI840350A FI840350A FI 840350 A FI840350 A FI 840350A FI 840350 A FI840350 A FI 840350A FI 840350 A FI840350 A FI 840350A FI 840350 A FI840350 A FI 840350A
Authority
FI
Finland
Prior art keywords
saolunda
racematisk
karboxialkyldipeptider
karbonsyraestrar
bicykliska
Prior art date
Application number
FI840350A
Other languages
English (en)
Other versions
FI88153B (fi
FI840350A0 (fi
FI88153C (fi
Inventor
Rolf Geiger
Volker Teetz
Dietrich Langner
Hansjoerg Urbach
Rainer Henning
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19833303139 external-priority patent/DE3303139A1/de
Priority claimed from DE19833303112 external-priority patent/DE3303112A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI840350A0 publication Critical patent/FI840350A0/fi
Publication of FI840350A publication Critical patent/FI840350A/fi
Priority to FI882285A priority Critical patent/FI882285A0/fi
Publication of FI88153B publication Critical patent/FI88153B/fi
Application granted granted Critical
Publication of FI88153C publication Critical patent/FI88153C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI840350A 1983-01-31 1984-01-27 Foerfarande foer racematisk avskiljning av optiskt aktiva bicykliska imino- -karboxylsyraestrar och saolunda erhaollna foereningar och deras anvaendning till syntes av karboxialkyldipeptider FI88153C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI882285A FI882285A0 (fi) 1983-01-31 1988-05-16 Foerfarande foer framstaellning av optiskt aktiva karboxialkyldipeptider.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19833303139 DE3303139A1 (de) 1983-01-31 1983-01-31 Verfahren zur herstellung von carboxyalkyldipeptiden
DE3303139 1983-01-31
DE19833303112 DE3303112A1 (de) 1983-01-31 1983-01-31 Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren
DE3303112 1983-01-31

Publications (4)

Publication Number Publication Date
FI840350A0 FI840350A0 (fi) 1984-01-27
FI840350A true FI840350A (fi) 1984-08-01
FI88153B FI88153B (fi) 1992-12-31
FI88153C FI88153C (fi) 1993-04-13

Family

ID=25807929

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840350A FI88153C (fi) 1983-01-31 1984-01-27 Foerfarande foer racematisk avskiljning av optiskt aktiva bicykliska imino- -karboxylsyraestrar och saolunda erhaollna foereningar och deras anvaendning till syntes av karboxialkyldipeptider

Country Status (17)

Country Link
EP (1) EP0115345B1 (fi)
JP (1) JPH0788358B2 (fi)
KR (1) KR910001438B1 (fi)
AU (1) AU566589B2 (fi)
CA (2) CA1283249C (fi)
DE (1) DE3468415D1 (fi)
DK (1) DK174386B1 (fi)
ES (2) ES529272A0 (fi)
FI (1) FI88153C (fi)
GR (1) GR82650B (fi)
HU (1) HU191120B (fi)
IE (1) IE56654B1 (fi)
IL (1) IL70830A (fi)
MA (1) MA20020A1 (fi)
NO (1) NO166641C (fi)
NZ (1) NZ206980A (fi)
PT (1) PT78036B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500713A (en) * 1982-09-23 1985-02-19 Usv Pharmaceutical Corporation Therapeutic dipeptides
DE3345355A1 (de) * 1983-12-15 1985-06-27 Hoechst Ag, 6230 Frankfurt Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester
AU581919B2 (en) * 1984-07-30 1989-03-09 Schering Corporation Process for the preparation of cis, endooctahydrocyclopenta (b) pyrrole-2-carboxylate
HU192914B (en) * 1985-02-11 1987-07-28 Richter Gedeon Vegyeszet Process for producing new 3-/substituted amino/-5-phenyl-2/3h/-furanone derivatives and pharmaceutically acceptable salts
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
US6407262B1 (en) 2001-11-21 2002-06-18 Brantford Chemicals Inc. Process for the preparation of Ramipril
WO2006059347A2 (en) * 2004-12-01 2006-06-08 Morepen Laboratories Limited Improved process for preparation of ramipril
US8558023B2 (en) 2010-04-20 2013-10-15 Chiral Quest, Inc. Enantioselective process for cycloalkenyl β-substituted alanines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids

Also Published As

Publication number Publication date
IL70830A0 (en) 1984-04-30
PT78036B (de) 1986-05-30
GR82650B (fi) 1985-02-07
DK174386B1 (da) 2003-01-27
EP0115345A1 (de) 1984-08-08
IE840210L (en) 1984-07-31
CA1317067C (en) 1993-04-27
ES531284A0 (es) 1984-12-01
ES8501759A1 (es) 1984-12-01
EP0115345B1 (de) 1988-01-07
IE56654B1 (en) 1991-10-23
ES8500228A1 (es) 1984-10-01
FI88153B (fi) 1992-12-31
KR910001438B1 (ko) 1991-03-07
PT78036A (de) 1984-02-01
JPH0517439A (ja) 1993-01-26
IL70830A (en) 1988-02-29
FI840350A0 (fi) 1984-01-27
NO840350L (no) 1984-08-01
MA20020A1 (fr) 1984-10-01
CA1283249C (en) 1991-04-16
NO166641B (no) 1991-05-13
DE3468415D1 (en) 1988-02-11
HUT34159A (en) 1985-02-28
DK41584A (da) 1984-08-01
HU191120B (en) 1987-01-28
AU2393384A (en) 1984-08-02
FI88153C (fi) 1993-04-13
AU566589B2 (en) 1987-10-22
NZ206980A (en) 1988-05-30
ES529272A0 (es) 1984-10-01
NO166641C (no) 1991-08-21
DK41584D0 (da) 1984-01-30
JPH0788358B2 (ja) 1995-09-27

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Owner name: HOECHST AKTIENGESELLSCHAFT