FI834771A - Kristalliserade kefem-syraadditionssalter och foerfarande foer deras framstaellning. - Google Patents

Kristalliserade kefem-syraadditionssalter och foerfarande foer deras framstaellning. Download PDF

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Publication number
FI834771A
FI834771A FI834771A FI834771A FI834771A FI 834771 A FI834771 A FI 834771A FI 834771 A FI834771 A FI 834771A FI 834771 A FI834771 A FI 834771A FI 834771 A FI834771 A FI 834771A
Authority
FI
Finland
Prior art keywords
kefem
syraadditionssalter
foerfarande foer
och foerfarande
deras framstaellning
Prior art date
Application number
FI834771A
Other languages
English (en)
Other versions
FI76094C (fi
FI76094B (fi
FI834771A0 (fi
Inventor
Walter Dyrckheimer
Rudolf Lattrell
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI834771A0 publication Critical patent/FI834771A0/fi
Publication of FI834771A publication Critical patent/FI834771A/fi
Application granted granted Critical
Publication of FI76094B publication Critical patent/FI76094B/fi
Publication of FI76094C publication Critical patent/FI76094C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI834771A 1982-12-28 1983-12-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara kristallina 7-(2-(2-aminotiazol-4-yl)-2- syn-metoxiiminoacetamido)-3-((2,3-cyklopenteno-1-pyridino)-metyl)- cef-3-em-4-karboxylat-syraadditionssalter. FI76094C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3248281 1982-12-28
DE19823248281 DE3248281A1 (de) 1982-12-28 1982-12-28 Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
FI834771A0 FI834771A0 (fi) 1983-12-23
FI834771A true FI834771A (fi) 1984-06-29
FI76094B FI76094B (fi) 1988-05-31
FI76094C FI76094C (fi) 1988-09-09

Family

ID=6181953

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834771A FI76094C (fi) 1982-12-28 1983-12-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara kristallina 7-(2-(2-aminotiazol-4-yl)-2- syn-metoxiiminoacetamido)-3-((2,3-cyklopenteno-1-pyridino)-metyl)- cef-3-em-4-karboxylat-syraadditionssalter.

Country Status (28)

Country Link
US (1) US4609653A (fi)
EP (1) EP0112550B1 (fi)
JP (1) JPH0723382B2 (fi)
KR (1) KR910000420B1 (fi)
AR (1) AR245133A1 (fi)
AT (1) ATE50261T1 (fi)
AU (1) AU562714B2 (fi)
CA (1) CA1235690A (fi)
CS (2) CS241070B2 (fi)
DD (1) DD215552A5 (fi)
DE (2) DE3248281A1 (fi)
DK (1) DK166211C (fi)
DZ (1) DZ592A1 (fi)
ES (1) ES8407495A1 (fi)
FI (1) FI76094C (fi)
GR (1) GR79444B (fi)
HU (1) HU191385B (fi)
IE (1) IE56488B1 (fi)
IL (1) IL70544A (fi)
MA (1) MA19990A1 (fi)
NO (1) NO834824L (fi)
NZ (1) NZ206704A (fi)
OA (1) OA07622A (fi)
PH (1) PH19269A (fi)
PT (1) PT77896B (fi)
SU (1) SU1292668A3 (fi)
YU (1) YU43200B (fi)
ZA (1) ZA839593B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
JPH0649707B2 (ja) * 1985-03-01 1994-06-29 第一製薬株式会社 ３−ピリジニウムメチルセフエム誘導体
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE4440141A1 (de) 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
BR0209065A (pt) * 2001-04-23 2004-08-10 Shionogi & Co Sulfato de composto de cefemo
JPWO2004039816A1 (ja) * 2002-10-29 2006-03-02 塩野義製薬株式会社 セフェム化合物の無機酸塩の結晶
CN101172982B (zh) * 2006-11-03 2011-06-08 河北凯盛医药科技有限公司 一种硫酸头孢匹罗的制备方法
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
CN101104621A (zh) * 2007-05-08 2008-01-16 深圳信立泰药业股份有限公司 制备高纯度硫酸头孢匹罗的工艺
CN101284840B (zh) * 2008-05-29 2012-07-04 管小明 硫酸头孢匹罗的合成方法
CN103044455B (zh) * 2011-10-17 2015-04-01 苏州中联化学制药有限公司 硫酸头孢匹罗混粉的返工方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS523091A (en) * 1975-06-23 1977-01-11 Takeda Chem Ind Ltd A prcess for preparing cephalosporins
CH654010A5 (de) * 1979-05-25 1986-01-31 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika.
BE885488A (fr) * 1979-10-02 1981-04-01 Glaxo Group Ltd Bischlorhydrate de cephalosporine et sa preparation
EP0062321B1 (en) * 1981-04-03 1989-03-01 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ES528401A0 (es) 1984-09-16
FI76094C (fi) 1988-09-09
AR245133A1 (es) 1993-12-30
DE3248281A1 (de) 1984-06-28
CS415791A3 (en) 1992-07-15
PT77896B (de) 1986-04-21
YU251183A (en) 1986-06-30
DK166211C (da) 1993-08-16
DK600183A (da) 1984-06-29
MA19990A1 (fr) 1984-07-01
NO834824L (no) 1984-06-29
FI76094B (fi) 1988-05-31
NZ206704A (en) 1986-04-11
CS241070B2 (en) 1986-03-13
KR910000420B1 (ko) 1991-01-25
OA07622A (fr) 1985-03-31
CA1235690A (en) 1988-04-26
KR840007016A (ko) 1984-12-04
CS997483A2 (en) 1985-07-16
IE56488B1 (en) 1991-08-14
DD215552A5 (de) 1984-11-14
DK600183D0 (da) 1983-12-27
EP0112550B1 (de) 1990-02-07
ZA839593B (en) 1984-08-29
IE833045L (en) 1984-06-28
FI834771A0 (fi) 1983-12-23
PT77896A (de) 1984-01-01
YU43200B (en) 1989-04-30
ATE50261T1 (de) 1990-02-15
DZ592A1 (fr) 2004-09-13
EP0112550A2 (de) 1984-07-04
HU191385B (en) 1987-02-27
JPH0723382B2 (ja) 1995-03-15
GR79444B (fi) 1984-10-30
HUT34211A (en) 1985-02-28
EP0112550A3 (en) 1985-09-18
DE3381201D1 (de) 1990-03-15
AU2289383A (en) 1984-07-05
SU1292668A3 (ru) 1987-02-23
JPS59130888A (ja) 1984-07-27
IL70544A (en) 1987-01-30
US4609653A (en) 1986-09-02
IL70544A0 (en) 1984-03-30
AU562714B2 (en) 1987-06-18
PH19269A (en) 1986-02-21
ES8407495A1 (es) 1984-09-16
DK166211B (da) 1993-03-22

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MA Patent expired

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH