DK600183D0 - Krystalliserede cephem-syreadditionssalte,deres fremstilling og anvendelse - Google Patents

Krystalliserede cephem-syreadditionssalte,deres fremstilling og anvendelse

Info

Publication number
DK600183D0
DK600183D0 DK6001/83A DK600183A DK600183D0 DK 600183 D0 DK600183 D0 DK 600183D0 DK 6001/83 A DK6001/83 A DK 6001/83A DK 600183 A DK600183 A DK 600183A DK 600183 D0 DK600183 D0 DK 600183D0
Authority
DK
Denmark
Prior art keywords
preparation
acid addition
addition salts
crystallized
cephem acid
Prior art date
Application number
DK6001/83A
Other languages
English (en)
Other versions
DK166211B (da
DK600183A (da
DK166211C (da
Inventor
Walter Duerckheimer
Rudolf Lattrell
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK600183D0 publication Critical patent/DK600183D0/da
Publication of DK600183A publication Critical patent/DK600183A/da
Publication of DK166211B publication Critical patent/DK166211B/da
Application granted granted Critical
Publication of DK166211C publication Critical patent/DK166211C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK600183A 1982-12-28 1983-12-27 Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse DK166211C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823248281 DE3248281A1 (de) 1982-12-28 1982-12-28 Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3248281 1982-12-28

Publications (4)

Publication Number Publication Date
DK600183D0 true DK600183D0 (da) 1983-12-27
DK600183A DK600183A (da) 1984-06-29
DK166211B DK166211B (da) 1993-03-22
DK166211C DK166211C (da) 1993-08-16

Family

ID=6181953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK600183A DK166211C (da) 1982-12-28 1983-12-27 Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse

Country Status (28)

Country Link
US (1) US4609653A (da)
EP (1) EP0112550B1 (da)
JP (1) JPH0723382B2 (da)
KR (1) KR910000420B1 (da)
AR (1) AR245133A1 (da)
AT (1) ATE50261T1 (da)
AU (1) AU562714B2 (da)
CA (1) CA1235690A (da)
CS (2) CS241070B2 (da)
DD (1) DD215552A5 (da)
DE (2) DE3248281A1 (da)
DK (1) DK166211C (da)
DZ (1) DZ592A1 (da)
ES (1) ES8407495A1 (da)
FI (1) FI76094C (da)
GR (1) GR79444B (da)
HU (1) HU191385B (da)
IE (1) IE56488B1 (da)
IL (1) IL70544A (da)
MA (1) MA19990A1 (da)
NO (1) NO834824L (da)
NZ (1) NZ206704A (da)
OA (1) OA07622A (da)
PH (1) PH19269A (da)
PT (1) PT77896B (da)
SU (1) SU1292668A3 (da)
YU (1) YU43200B (da)
ZA (1) ZA839593B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE150507T1 (de) * 1983-12-29 1987-02-26 Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
JPH0649707B2 (ja) * 1985-03-01 1994-06-29 第一製薬株式会社 ３−ピリジニウムメチルセフエム誘導体
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE4440141A1 (de) 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
WO2002088147A1 (fr) * 2001-04-23 2002-11-07 Shionogi & Co., Ltd. Sulfate d'un compose cepheme
WO2004039816A1 (ja) * 2002-10-29 2004-05-13 Shionogi & Co., Ltd. セフェム化合物の無機酸塩の結晶
CN101172982B (zh) * 2006-11-03 2011-06-08 河北凯盛医药科技有限公司 一种硫酸头孢匹罗的制备方法
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
CN101104621A (zh) * 2007-05-08 2008-01-16 深圳信立泰药业股份有限公司 制备高纯度硫酸头孢匹罗的工艺
CN101284840B (zh) * 2008-05-29 2012-07-04 管小明 硫酸头孢匹罗的合成方法
CN103044455B (zh) * 2011-10-17 2015-04-01 苏州中联化学制药有限公司 硫酸头孢匹罗混粉的返工方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS523091A (en) * 1975-06-23 1977-01-11 Takeda Chem Ind Ltd A prcess for preparing cephalosporins
CH654010A5 (de) * 1979-05-25 1986-01-31 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika.
IT1128569B (it) * 1979-10-02 1986-05-28 Glaxo Group Ltd Biscloridrato di cefalosporina,composizioni che lo contengono e relativo procedimento di preparazione ed applicazione
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
HU191385B (en) 1987-02-27
FI76094C (fi) 1988-09-09
CS997483A2 (en) 1985-07-16
PT77896B (de) 1986-04-21
DZ592A1 (fr) 2004-09-13
IE56488B1 (en) 1991-08-14
DE3248281A1 (de) 1984-06-28
FI76094B (fi) 1988-05-31
MA19990A1 (fr) 1984-07-01
AU562714B2 (en) 1987-06-18
EP0112550A3 (en) 1985-09-18
CS241070B2 (en) 1986-03-13
AU2289383A (en) 1984-07-05
EP0112550A2 (de) 1984-07-04
IL70544A0 (en) 1984-03-30
AR245133A1 (es) 1993-12-30
NO834824L (no) 1984-06-29
FI834771A (fi) 1984-06-29
HUT34211A (en) 1985-02-28
OA07622A (fr) 1985-03-31
GR79444B (da) 1984-10-30
DK166211B (da) 1993-03-22
US4609653A (en) 1986-09-02
FI834771A0 (fi) 1983-12-23
CS415791A3 (en) 1992-07-15
ZA839593B (en) 1984-08-29
SU1292668A3 (ru) 1987-02-23
JPS59130888A (ja) 1984-07-27
PT77896A (de) 1984-01-01
IL70544A (en) 1987-01-30
CA1235690A (en) 1988-04-26
ATE50261T1 (de) 1990-02-15
DK600183A (da) 1984-06-29
YU43200B (en) 1989-04-30
KR840007016A (ko) 1984-12-04
KR910000420B1 (ko) 1991-01-25
NZ206704A (en) 1986-04-11
ES528401A0 (es) 1984-09-16
DK166211C (da) 1993-08-16
YU251183A (en) 1986-06-30
JPH0723382B2 (ja) 1995-03-15
ES8407495A1 (es) 1984-09-16
DE3381201D1 (de) 1990-03-15
IE833045L (en) 1984-06-28
EP0112550B1 (de) 1990-02-07
PH19269A (en) 1986-02-21
DD215552A5 (de) 1984-11-14

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