DK600183A - Krystalliserede cephem-syreadditionssalte, deres fremstilling og anvendelse - Google Patents

Krystalliserede cephem-syreadditionssalte, deres fremstilling og anvendelse Download PDF

Info

Publication number
DK600183A
DK600183A DK600183A DK600183A DK600183A DK 600183 A DK600183 A DK 600183A DK 600183 A DK600183 A DK 600183A DK 600183 A DK600183 A DK 600183A DK 600183 A DK600183 A DK 600183A
Authority
DK
Denmark
Prior art keywords
preparation
acid addition
addition salts
crystallized
cephem acid
Prior art date
Application number
DK600183A
Other languages
English (en)
Other versions
DK166211C (da
DK166211B (da
DK600183D0 (da
Inventor
Walter Duerckheimer
Rudolf Lattrell
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK600183D0 publication Critical patent/DK600183D0/da
Publication of DK600183A publication Critical patent/DK600183A/da
Publication of DK166211B publication Critical patent/DK166211B/da
Application granted granted Critical
Publication of DK166211C publication Critical patent/DK166211C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK600183A 1982-12-28 1983-12-27 Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse DK166211C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3248281 1982-12-28
DE19823248281 DE3248281A1 (de) 1982-12-28 1982-12-28 Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
DK600183D0 DK600183D0 (da) 1983-12-27
DK600183A true DK600183A (da) 1984-06-29
DK166211B DK166211B (da) 1993-03-22
DK166211C DK166211C (da) 1993-08-16

Family

ID=6181953

Family Applications (1)

Application Number Title Priority Date Filing Date
DK600183A DK166211C (da) 1982-12-28 1983-12-27 Krystalliseret cephem-syreadditionssalt, dets fremstilling og anvendelse

Country Status (28)

Country Link
US (1) US4609653A (da)
EP (1) EP0112550B1 (da)
JP (1) JPH0723382B2 (da)
KR (1) KR910000420B1 (da)
AR (1) AR245133A1 (da)
AT (1) ATE50261T1 (da)
AU (1) AU562714B2 (da)
CA (1) CA1235690A (da)
CS (2) CS241070B2 (da)
DD (1) DD215552A5 (da)
DE (2) DE3248281A1 (da)
DK (1) DK166211C (da)
DZ (1) DZ592A1 (da)
ES (1) ES8407495A1 (da)
FI (1) FI76094C (da)
GR (1) GR79444B (da)
HU (1) HU191385B (da)
IE (1) IE56488B1 (da)
IL (1) IL70544A (da)
MA (1) MA19990A1 (da)
NO (1) NO834824L (da)
NZ (1) NZ206704A (da)
OA (1) OA07622A (da)
PH (1) PH19269A (da)
PT (1) PT77896B (da)
SU (1) SU1292668A3 (da)
YU (1) YU43200B (da)
ZA (1) ZA839593B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
JPH0649707B2 (ja) * 1985-03-01 1994-06-29 第一製薬株式会社 ３−ピリジニウムメチルセフエム誘導体
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE4440141A1 (de) * 1994-11-10 1996-05-15 Hoechst Ag Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
BR0209065A (pt) * 2001-04-23 2004-08-10 Shionogi & Co Sulfato de composto de cefemo
AU2003275682A1 (en) * 2002-10-29 2004-05-25 Shionogi And Co., Ltd. Crystal of inorganic acid salt of cephem compound
CN101172982B (zh) * 2006-11-03 2011-06-08 河北凯盛医药科技有限公司 一种硫酸头孢匹罗的制备方法
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
CN101104621A (zh) * 2007-05-08 2008-01-16 深圳信立泰药业股份有限公司 制备高纯度硫酸头孢匹罗的工艺
CN101284840B (zh) * 2008-05-29 2012-07-04 管小明 硫酸头孢匹罗的合成方法
CN103044455B (zh) * 2011-10-17 2015-04-01 苏州中联化学制药有限公司 硫酸头孢匹罗混粉的返工方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS523091A (en) * 1975-06-23 1977-01-11 Takeda Chem Ind Ltd A prcess for preparing cephalosporins
FR2457295A1 (fr) * 1979-05-25 1980-12-19 Glaxo Group Ltd Composes intermediaires pour la preparation de cephalosporines
SE449996B (sv) * 1979-10-02 1987-06-01 Glaxo Group Ltd (6r,7r)-7-/(z)-2-(2-aminotiazol-4-yl)-2-(2-karboxiprop-2-oxiimino)acetamidol/-3-(1-pyridiniummetyl)cef-3-em-4-karboxylat i form av en kristallin bishydroklorid farmaceutisk komposition derav samt anvendning som mellanpr
ES8306160A1 (es) * 1981-04-03 1983-05-01 Fujisawa Pharmaceutical Co "procedimiento para preparar un nuevo compuesto de cefem".
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AU562714B2 (en) 1987-06-18
IL70544A (en) 1987-01-30
NO834824L (no) 1984-06-29
FI76094B (fi) 1988-05-31
IE833045L (en) 1984-06-28
ES528401A0 (es) 1984-09-16
HUT34211A (en) 1985-02-28
ES8407495A1 (es) 1984-09-16
AR245133A1 (es) 1993-12-30
DK166211C (da) 1993-08-16
FI834771A0 (fi) 1983-12-23
DD215552A5 (de) 1984-11-14
FI76094C (fi) 1988-09-09
CA1235690A (en) 1988-04-26
JPS59130888A (ja) 1984-07-27
ATE50261T1 (de) 1990-02-15
PT77896B (de) 1986-04-21
FI834771A (fi) 1984-06-29
EP0112550A3 (en) 1985-09-18
DZ592A1 (fr) 2004-09-13
GR79444B (da) 1984-10-30
KR840007016A (ko) 1984-12-04
ZA839593B (en) 1984-08-29
EP0112550B1 (de) 1990-02-07
CS241070B2 (en) 1986-03-13
OA07622A (fr) 1985-03-31
US4609653A (en) 1986-09-02
IE56488B1 (en) 1991-08-14
YU43200B (en) 1989-04-30
IL70544A0 (en) 1984-03-30
PT77896A (de) 1984-01-01
JPH0723382B2 (ja) 1995-03-15
DK166211B (da) 1993-03-22
DE3381201D1 (de) 1990-03-15
SU1292668A3 (ru) 1987-02-23
DE3248281A1 (de) 1984-06-28
PH19269A (en) 1986-02-21
DK600183D0 (da) 1983-12-27
HU191385B (en) 1987-02-27
MA19990A1 (fr) 1984-07-01
EP0112550A2 (de) 1984-07-04
KR910000420B1 (ko) 1991-01-25
YU251183A (en) 1986-06-30
NZ206704A (en) 1986-04-11
AU2289383A (en) 1984-07-05
CS997483A2 (en) 1985-07-16
CS415791A3 (en) 1992-07-15

Similar Documents

Publication Publication Date Title
DK600183A (da) Krystalliserede cephem-syreadditionssalte, deres fremstilling og anvendelse
DK379481A (da) Phosphotsyremonoestersalte deres fremstilling og anvendelse som fungicider
DK522983D0 (da) Arylphenyletherderivater og syreadditionssalte deraf samt fremgangsmade til fremstilling deraf
DK227884A (da) 1-pyrimidinyloxy-3-hetarylalkylamino-2-propanoler, deres fremstilling og anvendelse
DK26784A (da) Aminosyrederivater, deres fremstilling og anvendelse
DK567983A (da) 2-hydroxymethyl-3-carbamoyl-1,4-dihydro-pyridin-forbindelser og salte deraf samt deres fremstilling og anvendelse
DK95788A (da) Krystalliserede cephem-syreadditionssalte, deres fremstilling og anvendelse
DK256085A (da) Cephemforbindelser og salte og estere deraf, samt deres fremstilling og anvendelse
DK172183D0 (da) Ozazolderivater, deres fremstilling og anvendelse
NO834210L (no) Limsammensetninger inneholdende maursyresalt, fremgangsmaater, og papir limt med slike sammensetninger
DK543084A (da) Substituerede 3-carbamoyl-1,4-dihydropyridin-forbindelser og saltederaf samt deres fremstilling og anvendelse
DK209384D0 (da) 4-phenyl-tetrahydro-furano-pyridiner og syreadditionssalte deraf,fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
DK310883A (da) Phenyleddikesyrederivater, deres fremstilling og anvendelse
DK299983D0 (da) Racemiske eller optisk aktive apovincaminsyrederivater eller farmaceutisk aktive syreadditionssalte deraf, deres fremstilling og anvendelse
NO830981L (no) Pentandionsyrederivater og fremgangsmaate for deres fremstilling.
DK325687D0 (da) Hydrogenerede 1-phenoxyalkylpyridin-3-carboxylsyreforbindelser og salte deraf samt deres fremstilling og anvendelse
DK559183A (da) Cycloalkenylderivater, deres fremstilling og anvendelse
DK351284A (da) Substituerede thiazolidinylestere af mineralsyreamider og salte deraf samt deres fremstilling og anvendelse
DK181683D0 (da) Arylcycloalkylether-derivater, deres anvendelse og fremstilling
DK300583A (da) Racemiske eller optisk aktive eburnanoximderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse
DK174684D0 (da) 7beta-acylamido-3-cephem-4-carboxylsyreforbindelser samt deres fremstilling og anvendelse
DK485683A (da) Benzodioxolderivater og syreadditionssalte deraf samt fremgangsmaade til fremstilling deraf
DK292086D0 (da) 2-halogennicergolinderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse
DK350284D0 (da) 1-phenylimidazolidin-2-on-derivater, deres fremstilling og anvendelse
DK300383D0 (da) Racemiske eller optisk aktive ehomo-eburanderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse

Legal Events

Date Code Title Description
PUP Patent expired