FI832602A0 - Nya 2-aza-bicyklo/2,2,2/oktan-3-karbonsyraderivat, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt aza-bicyclo/2,2,2/oktan-3-karbonsyra saosom mellanprodukt och foerfaranden foer deras framstaellning - Google Patents

Nya 2-aza-bicyklo/2,2,2/oktan-3-karbonsyraderivat, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt aza-bicyclo/2,2,2/oktan-3-karbonsyra saosom mellanprodukt och foerfaranden foer deras framstaellning

Info

Publication number
FI832602A0
FI832602A0 FI832602A FI832602A FI832602A0 FI 832602 A0 FI832602 A0 FI 832602A0 FI 832602 A FI832602 A FI 832602A FI 832602 A FI832602 A FI 832602A FI 832602 A0 FI832602 A0 FI 832602A0
Authority
FI
Finland
Prior art keywords
aza
bicyclo
framstaellning
deras
karbons
Prior art date
Application number
FI832602A
Other languages
English (en)
Other versions
FI832602A (fi
Inventor
Rainer Henning
Hansjoerg Urbach
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI832602A0 publication Critical patent/FI832602A0/fi
Publication of FI832602A publication Critical patent/FI832602A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI832602A 1982-07-20 1983-07-18 Nya 2-aza-bicyklo/2,2,2/oktan-3-karbonsyraderivat, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt aza-bicyklo/2,2,2/oktan-3-karbonsyra saosom mellanprodukt och foerfaranden foer deras framstaellning FI832602A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823227055 DE3227055A1 (de) 1982-07-20 1982-07-20 Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
FI832602A0 true FI832602A0 (fi) 1983-07-18
FI832602A FI832602A (fi) 1984-01-21

Family

ID=6168834

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832602A FI832602A (fi) 1982-07-20 1983-07-18 Nya 2-aza-bicyklo/2,2,2/oktan-3-karbonsyraderivat, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning, samt aza-bicyklo/2,2,2/oktan-3-karbonsyra saosom mellanprodukt och foerfaranden foer deras framstaellning

Country Status (13)

Country Link
EP (1) EP0105102A1 (fi)
JP (1) JPS5929686A (fi)
KR (1) KR840005429A (fi)
AU (1) AU1699383A (fi)
DE (1) DE3227055A1 (fi)
DK (1) DK333083A (fi)
ES (2) ES524214A0 (fi)
FI (1) FI832602A (fi)
GR (1) GR78901B (fi)
IL (1) IL69271A0 (fi)
NO (1) NO832648L (fi)
PT (1) PT77058B (fi)
ZA (1) ZA835237B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3410732A1 (de) * 1984-03-23 1985-09-26 Hoechst Ag, 6230 Frankfurt Methode zur behandlung des glaukoms
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
WO1990002123A1 (en) * 1988-08-23 1990-03-08 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DK0796855T3 (da) 1996-03-20 2002-05-27 Hoechst Ag Hæmmere af knogleresorption og vitronectin-receptorantagonister
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
KR20030016310A (ko) * 2000-06-28 2003-02-26 브리스톨-마이어스스퀴브컴파니 선택적 안드로겐 수용체 조절제, 및 그의 확인, 고안 및사용 방법
US20030114420A1 (en) * 2000-06-28 2003-06-19 Salvati Mark E. Fused cyclic modulators of nuclear hormone receptor function
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Also Published As

Publication number Publication date
DK333083A (da) 1984-01-21
ES8404351A1 (es) 1984-05-01
ES8404352A1 (es) 1984-05-01
ES524215A0 (es) 1984-05-01
FI832602A (fi) 1984-01-21
EP0105102A1 (de) 1984-04-11
ZA835237B (en) 1984-03-28
KR840005429A (ko) 1984-11-12
ES524214A0 (es) 1984-05-01
DK333083D0 (da) 1983-07-19
PT77058A (de) 1983-08-01
PT77058B (de) 1986-02-26
GR78901B (fi) 1984-10-02
JPS5929686A (ja) 1984-02-16
IL69271A0 (en) 1983-11-30
NO832648L (no) 1984-01-23
DE3227055A1 (de) 1984-01-26
AU1699383A (en) 1984-01-26

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Owner name: HOECHST AKTIENGESELLSCHAFT