IL69271A0 - New derivatives of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,process for their preparation,agents containing these derivatives and the use thereof,and of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,as an intermediate stage and process for the preparation thereof - Google Patents

New derivatives of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,process for their preparation,agents containing these derivatives and the use thereof,and of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,as an intermediate stage and process for the preparation thereof

Info

Publication number
IL69271A0
IL69271A0 IL69271A IL6927183A IL69271A0 IL 69271 A0 IL69271 A0 IL 69271A0 IL 69271 A IL69271 A IL 69271A IL 6927183 A IL6927183 A IL 6927183A IL 69271 A0 IL69271 A0 IL 69271A0
Authority
IL
Israel
Prior art keywords
azabicyclo
octane
preparation
carboxylic acid
derivatives
Prior art date
Application number
IL69271A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL69271A0 publication Critical patent/IL69271A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL69271A 1982-07-20 1983-07-19 New derivatives of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,process for their preparation,agents containing these derivatives and the use thereof,and of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,as an intermediate stage and process for the preparation thereof IL69271A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823227055 DE3227055A1 (de) 1982-07-20 1982-07-20 Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
IL69271A0 true IL69271A0 (en) 1983-11-30

Family

ID=6168834

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69271A IL69271A0 (en) 1982-07-20 1983-07-19 New derivatives of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,process for their preparation,agents containing these derivatives and the use thereof,and of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,as an intermediate stage and process for the preparation thereof

Country Status (13)

Country Link
EP (1) EP0105102A1 (xx)
JP (1) JPS5929686A (xx)
KR (1) KR840005429A (xx)
AU (1) AU1699383A (xx)
DE (1) DE3227055A1 (xx)
DK (1) DK333083A (xx)
ES (2) ES8404352A1 (xx)
FI (1) FI832602A (xx)
GR (1) GR78901B (xx)
IL (1) IL69271A0 (xx)
NO (1) NO832648L (xx)
PT (1) PT77058B (xx)
ZA (1) ZA835237B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3410732A1 (de) * 1984-03-23 1985-09-26 Hoechst Ag, 6230 Frankfurt Methode zur behandlung des glaukoms
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
FR2619813B1 (fr) * 1987-08-28 1991-05-03 Adir Nouveaux derives de l'acide aza - 2 bicyclooctane carboxylique - 3, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
WO1990002123A1 (en) * 1988-08-23 1990-03-08 Pfizer Inc. Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters
FR2635684A1 (fr) * 1988-08-24 1990-03-02 Adir Utilisation de derives de l'acide aza - 2 bicyclooctane (2.2.2) carboxylique - 3 pour l'obtention de medicaments destines au traitement des maladies consecutives a l'alteration de la paroi vasculaire ainsi qu'aux troubles de la microcirculation
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE59706273D1 (de) 1996-03-20 2002-03-21 Hoechst Ag Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
SE0000382D0 (sv) 2000-02-07 2000-02-07 Astrazeneca Ab New process
US20030114420A1 (en) * 2000-06-28 2003-06-19 Salvati Mark E. Fused cyclic modulators of nuclear hormone receptor function
MXPA02012605A (es) * 2000-06-28 2003-05-14 Squibb Bristol Myers Co Moduladores selectivos del receptor androgeno y metodo para su identificacion, dise°o y uso.
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Also Published As

Publication number Publication date
PT77058B (de) 1986-02-26
ES8404351A1 (es) 1984-05-01
DE3227055A1 (de) 1984-01-26
NO832648L (no) 1984-01-23
GR78901B (xx) 1984-10-02
DK333083D0 (da) 1983-07-19
ES524215A0 (es) 1984-05-01
JPS5929686A (ja) 1984-02-16
AU1699383A (en) 1984-01-26
FI832602A0 (fi) 1983-07-18
EP0105102A1 (de) 1984-04-11
ZA835237B (en) 1984-03-28
KR840005429A (ko) 1984-11-12
PT77058A (de) 1983-08-01
DK333083A (da) 1984-01-21
ES524214A0 (es) 1984-05-01
FI832602A (fi) 1984-01-21
ES8404352A1 (es) 1984-05-01

Similar Documents

Publication Publication Date Title
IL69271A0 (en) New derivatives of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,process for their preparation,agents containing these derivatives and the use thereof,and of 2-azabicyclo(2,2,2)octane-3-carboxylic acid,as an intermediate stage and process for the preparation thereof
DE3060592D1 (en) Derivatives of 2,4,6-triodo-isophthalic acid, process for their preparation and x-ray contrast agents containing them
DE3061347D1 (en) 2,4,6-triiodo-isophthalic acid derivatives, process for their preparation and x-ray contrast agents containing them
DE3372769D1 (en) 3-aminoquinuclidin derivatives, process for their preparation and their use as therapeutical agents
DE3368060D1 (en) O-halobenzoic acid derivatives, process for their preparation, herbicidal compositions and their use
PT79187A (en) Process for preparing 1-heteroaryl-4-<(2,5-pyrrolidinedion-1-yl)-alkyl>-piperazine derivatives and of pharmaceutical compositions containing the same
PT76831A (en) Process for preparing teichomycin a2 pure single factors 1,2,3,4 and 5 and of pharmaceutical compositions containing the same
PT86362A (en) Process for the preparation of anxiolytic compositions containing n-(1-azabicyclo ]2,2.2."-oct-3-yl) benzamides and thiobenzamides
PT76523B (en) Process for preparing phenoxyalkylcarboxylic acid derivatives and of pharmaceutical compositions containing the same
PT76809A (en) Process for preparing 1-sulfo-2-oxoazetidine derivatives and of pharmaceutical compositions containing the same
PT84364A (en) Process for the preparation of 1h-imidazole-5-carboxylic acid derivatives and herbicide compositions therewith
PT76657B (en) Process for preparing 4-aryl-4-piperidinecarbinols and of pharmaceutical compositions containing the same
PT76870B (en) Process for the preparation of 1,4-dihydropiridine derivatives and pharmaceutical compositions containing them
PT79389B (en) Process for the preparation of 1,2-dithyolane derivates and pharmaceutical compositions containing said derivates
PT79113B (en) Process for the preparation of 16-fluoro-16,17-didehydro prostanoids and of pharmaceutical compositions containing the same
EP0113880A3 (en) Derivatives from 2-azabicyclo(2.2.1)heptane, process for their preparation, agents containing them and their use, and 2-azabicyclo(2.2.1)heptane derivatives as intermediates, and process for their preparation
DE3365690D1 (en) Process for the preparation of 3,4,9,10-tetrathioperylene and 3,4,9,10-tetraselenoperylene
IL91986A0 (en) 2-azabicyclo(2.2.1)hept-5-ene-2-acetic acid,derivatives thereof and related compounds,process for the preparation of said compounds and the use of said compounds for the manufacture of n-phosphonomethylglycine
PT74400A (en) Process for the preparation of 17,18-dehydro-apovincaminol-3', 4',5'-trimethoxy-benzoate and of pharmaceutical compositions containing them
PT77282B (en) Process for preparing substituted 1-pyridyloxy-3-indolylalkylamino-2-propanols and of pharmaceutical compositions containing the same
PT76161A (en) Process for the preparation of herbicide derivatives of cyclohexane-1,3-dione-5-phenyl substituted and herbicide compositions thereof
DE3369132D1 (en) Process for the preparation of isomelamines, and their use
ZA837286B (en) 15-cycloaliphatic derivatives of 13,14-didehydro-carboprostacyclins and process for their preparation
PT77946A (en) Process for preparing substituted carboxi-thiazolo<3,2-a>pyrimidine derivatives and of pharmaceutical compositions containing the same
PT77730B (en) Process for preparing acridanone derivatives and of pharmaceutical compositions containing the same